Search Results - "WEISSMAN, B. E"
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KiSS-1, a Novel Human Malignant Melanoma Metastasis-Suppressor Gene
Published in JNCI : Journal of the National Cancer Institute (04-12-1996)“…Background Microcell-mediated transfer of chromosome 6 into human C8161 and MelJuSo melanoma cells suppresses their ability to metastasize by at least 95%…”
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2
BRG1 loss in MiaPaCa2 cells induces an altered cellular morphology and disruption in the organization of the actin cytoskeleton
Published in Journal of cellular physiology (01-11-2005)“…BRG1 and Brahma are critical and mutually exclusive subunits of the multi‐constituent SWI/SNF chromatin remodeling complexes. These complexes play a key role…”
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3
Chromosome Localization and Genomic Structure of the KiSS-1 Metastasis Suppressor Gene (KISS1)
Published in Genomics (San Diego, Calif.) (15-11-1998)“…The identification and sequence of KiSS-1 (HGMW-approved symbol, KISS1), a human malignant melanoma metastasis-suppressor gene, was recently published. In this…”
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4
Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and primary rhabdomyosarcomas but not Wilms' tumors
Published in Oncogene (09-12-1999)“…The organization of genomic DNA into chromatin aids in the regulation of gene expression by limiting the access of transcriptional binding domains. The SWI/SNF…”
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5
Selective inhibition of growth-related gene expression in murine keratinocytes by transforming growth factor beta
Published in Molecular and Cellular Biology (01-08-1988)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
KAI1, a putative marker for metastatic potential in human breast cancer
Published in Cancer letters (11-11-1997)“…The KAI1 gene maps to chromosome 11p11.2, is a metastasis-suppressor gene for human prostate cancer and also is involved in the progression of human pancreatic…”
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7
A human melanoma metastasis‐suppressor locus maps to 6q16.3‐q23
Published in International journal of cancer (15-05-2000)“…Loss, deletion or rearrangement along large portions of the long arm (q‐arm) of chromosome 6 occurs in >80% of late‐stage human melanomas, suggesting that…”
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Functional Characterization of Human Nucleosome Assembly Protein-2 (NAP1L4) Suggests a Role as a Histone Chaperone
Published in Genomics (San Diego, Calif.) (15-09-1997)“…Histones are thought to play a key role in regulating gene expression at the level of DNA packaging. Recent evidence suggests that transcriptional activation…”
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9
Human Chromosome 11 Contains Two Different Growth Suppressor Genes for Embryonal Rhabdomyosarcoma
Published in Proceedings of the National Academy of Sciences - PNAS (01-03-1992)“…The identification of acquired homozygosity in human cancers implies locations of tumor suppressor genes without providing functional evidence. The…”
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10
Suppression of MDA-MB-435 breast carcinoma cell metastasis following the introduction of human chromosome 11
Published in Cancer research (Chicago, Ill.) (15-03-1996)“…To determine the relevance of genetic information on chromosome 11 in the development of metastatic breast tumors, we introduced a normal human chromosome 11…”
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Divergently Transcribed Overlapping Genes Expressed in Liver and Kidney and Located in the 11p15.5 Imprinted Domain
Published in Genomics (San Diego, Calif.) (01-04-1998)“…Human chromosomal band 11p15.5 has been shown to contain genes involved in the development of several pediatric and adult tumors and in Beckwith–Wiedemann…”
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12
Chromosome 18 suppresses prostate cancer metastases
Published in Urologic oncology (01-09-2003)“…Loss of heterozygosity and allelic imbalance data has shown that there are two distinct regions of loss on chromosome 18q associated with the progression of…”
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13
Introduction of a Normal Human Chromosome 11 into a Wilms' Tumor Cell Line Controls its Tumorigenic Expression
Published in Science (American Association for the Advancement of Science) (10-04-1987)“…The development of Wilms' tumor, a pediatric nephroblastoma, has been associated with a deletion in the p13 region of chromosome 11. The structure and function…”
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14
Functional evidence for a second tumor suppressor gene on human chromosome 17
Published in Molecular and Cellular Biology (01-01-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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15
Growth modulation of mouse keratinocytes by transforming growth factors
Published in Cancer research (Chicago, Ill.) (15-03-1988)“…The effects of exogenously added transforming growth factor (TGF alpha and TGF beta on the growth of BALB/MK cells were examined. TGF alpha supplanted the…”
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16
A 1-Mb Physical Map and PAC Contig of the Imprinted Domain in 11p15.5 That Contains TAPA1 and the BWSCR1/WT2 Region
Published in Genomics (San Diego, Calif.) (01-08-1997)“…We have constructed a 1-Mb contig in human chromosomal band 11p15.5, a region implicated in the etiology of several embryonal tumors, including Wilms tumor,…”
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17
Localization of a Tumor Suppressor Gene in 11p15.5 Using the G401 Wilms' Tumor Assay
Published in Human molecular genetics (01-02-1996)“…Multiple studies have underscored the importance of loss of tumor suppressor genes in the development of human cancer. To identify these genes, we used somatic…”
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18
BRG-1 Is Required for RB-Mediated Cell Cycle Arrest
Published in Proceedings of the National Academy of Sciences - PNAS (05-07-2000)“…The antiproliferative action of the retinoblastoma tumor suppressor protein, RB, is disrupted in the majority of human cancers. Disruption of RB activity…”
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19
Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies
Published in Journal of cellular physiology (01-01-2001)“…Organization of genomic DNA into chromatin aids in the regulation of gene expression by limiting access to transcriptional machinery. The SWI/SNF family of…”
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20
Localization and characterization of a chromosome 11 tumor suppressor gene using organotypic raft cultures
Published in Cancer research (Chicago, Ill.) (15-03-1997)“…The development and progression of human cancer often involves the inactivation of tumor suppressor gene function. Alterations in human chromosome 11 during…”
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