Search Results - "WEISS, John"

A Novel Methodology for Improving Plant Pest Surveillance in Vineyards and Crops Using UAV-Based Hyperspectral and Spatial Data by Vanegas, Fernando, Bratanov, Dmitry, Powell, Kevin, Weiss, John, Gonzalez, Felipe

“…Recent advances in remote sensed imagery and geospatial image processing using unmanned aerial vehicles (UAVs) have enabled the rapid and ongoing development…”
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Zn2+ entry through the mitochondrial calcium uniporter is a critical contributor to mitochondrial dysfunction and neurodegeneration by Ji, Sung G., Medvedeva, Yuliya V., Weiss, John H.

“…Excitotoxic Ca2+ accumulation contributes to ischemic neurodegeneration, and Ca2+ can enter the mitochondria through the mitochondrial calcium uniporter (MCU)…”
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Zinc: new clues to diverse roles in brain ischemia by Shuttleworth, C. William, Weiss, John H

“…Cerebral ischemia is a leading cause of morbidity and mortality, reflecting the extraordinary sensitivity of the brain to a brief loss of blood flow. A…”
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Calcium-permeable AMPA channels in neurodegenerative disease and ischemia by Kwak, Shin, Weiss, John H

“…Compelling evidence supports contributions of glutamate receptor overactivation (‘excitotoxicity’) to neurodegeneration in both acute conditions, such as…”
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Zn2+-induced disruption of neuronal mitochondrial function: Synergism with Ca2+, critical dependence upon cytosolic Zn2+ buffering, and contributions to neuronal injury by Ji, Sung G., Weiss, John H.

“…Excitotoxic Zn2+ and Ca2+ accumulation contributes to neuronal injury after ischemia or prolonged seizures. Synaptically released Zn2+ can enter postsynaptic…”
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Mechanisms of rapid reactive oxygen species generation in response to cytosolic Ca2+ or Zn2+ loads in cortical neurons by Clausen, Aaron, McClanahan, Taylor, Ji, Sung G, Weiss, John H

“…Excessive "excitotoxic" accumulation of Ca(2+) and Zn(2+) within neurons contributes to neurodegeneration in pathological conditions including ischemia…”
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Intramitochondrial Zn2+ accumulation via the Ca2+ uniporter contributes to acute ischemic neurodegeneration by Medvedeva, Yuliya V., Weiss, John H.

“…Ca2+ and Zn2+ have both been implicated in the induction of acute ischemic neurodegeneration. We recently examined changes in intracellular Zn2+ and Ca2+ in…”
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Ca2+ Permeable AMPA Channels in Diseases of the Nervous System by Weiss, John H.

“…Since the discovery and molecular characterization of Ca2+ permeable AMPA channels just over 2 decades ago, a large body of evidence has accumulated…”
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Mitochondrial Zn2+ Accumulation: A Potential Trigger of Hippocampal Ischemic Injury by Ji, Sung G., Medvedeva, Yuliya V., Wang, Hwai-Lee, Yin, Hong Z., Weiss, John H.

“…Ischemic stroke is a major cause of death and disabilities worldwide, and it has been long hoped that improved understanding of relevant injury mechanisms…”
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Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord by Rossi, Sharyn L, Nistor, Gabriel, Wyatt, Tanya, Yin, Hong Zhen, Poole, Aleksandra J, Weiss, John H, Gardener, Matthew J, Dijkstra, Sipke, Fischer, David F, Keirstead, Hans S

“…Motor neuron loss is characteristic of cervical spinal cord injury (SCI) and contributes to functional deficit. In order to investigate the amenability of the…”
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Editorial: Excitotoxicity Turns 50. The Death That Never Dies by Granzotto, Alberto, Weiss, John H, Sensi, Stefano L

“…The review highlights three major findings: (1) the discovery of redox-dependent modulatory sites of NMDAR, (2) the oxidative-driven conversion of…”
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17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen–glucose deprivation/reperfusion by Guo, Jiabin, Duckles, Sue P., Weiss, John H., Li, Xuejun, Krause, Diana N.

“…17β-Estradiol (E2) has been shown to protect against ischemic brain injury, yet its targets and the mechanisms are unclear. E2 may exert multiple regulatory…”
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Intracellular Zn2+ Accumulation Contributes to Synaptic Failure, Mitochondrial Depolarization, and Cell Death in an Acute Slice Oxygen-Glucose Deprivation Model of Ischemia by Medvedeva, Yuliya V, Lin, Bin, Shuttleworth, C. William, Weiss, John H

“…Despite considerable evidence for contributions of both Zn(2+) and Ca(2+) in ischemic brain damage, the relative importance of each cation to very early events…”
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BMAA selectively injures motor neurons via AMPA/kainate receptor activation by Rao, Shyam D., Banack, Sandra Anne, Cox, Paul Alan, Weiss, John H.

“…The toxin beta-methylamino- l-alanine (BMAA) has been proposed to contribute to amyotrophic lateral sclerosis–Parkinsonism Dementia Complex of Guam (ALS/PDC)…”
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Anti-SARS-CoV-2 IgG and IgA antibodies in COVID-19 convalescent plasma do not enhance viral infection by Clark, Natasha M, Janaka, Sanath Kumar, Hartman, William, Stramer, Susan, Goodhue, Erin, Weiss, John, Evans, David T, Connor, Joseph P

“…The novel coronavirus, SARS-CoV-2 that causes COVID-19 has resulted in the death of nearly 4 million people within the last 18 months. While preventive…”
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Transmission of Babesia microti Parasites by Solid Organ Transplantation by Brennan, Meghan B, Herwaldt, Barbara L, Kazmierczak, James J, Weiss, John W, Klein, Christina L, Leith, Catherine P, He, Rong, Oberley, Matthew J, Tonnetti, Laura, Wilkins, Patricia P, Gauthier, Gregory M

“…Babesia microti, an intraerythrocytic parasite, is tickborne in nature. In contrast to transmission by blood transfusion, which has been well documented,…”
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The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction by Liu, Hilary Y, Gale, Jenna R, Reynolds, Ian J, Weiss, John H, Aizenman, Elias

“…Zinc is a highly abundant cation in the brain, essential for cellular functions, including transcription, enzymatic activity, and cell signaling. However, zinc…”
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Blocking Mitochondrial Zn2+ Accumulation after Ischemia Reduces Mitochondrial Dysfunction and Neuronal Injury by Medvedeva, Yuliya V, Yin, Hong Z, Bazrafkan, Afsheen, Yeromin, Andriy, Ji, Sung G, Weiss-Hung, Eli J, Sharman, Edward, Avilez, Alyssa P, Maki, Niki, Rafi, Masih A, Tian, Guilian, Akbari, Yama, Weiss, John H

“…Zn2+ is an important contributor to ischemic brain injury, and recent studies support the hypothesis that mitochondria are key sites of its injurious effects…”
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Intrathecal infusion of BMAA induces selective motor neuron damage and astrogliosis in the ventral horn of the spinal cord by Yin, Hong Z., Yu, Stephen, Hsu, Cheng-I, Liu, Joe, Acab, Allan, Wu, Richard, Tao, Anna, Chiang, Benjamin J., Weiss, John H.

“…The neurotoxin beta-N-methylamino-l-alanine (BMAA) was first identified as a “toxin of interest” in regard to the amyotrophic lateral sclerosis–Parkinsonism…”
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Blocking Mitochondrial Zn 2+ Accumulation after Ischemia Reduces Mitochondrial Dysfunction and Neuronal Injury by Medvedeva, Yuliya V, Yin, Hong Z, Bazrafkan, Afsheen, Yeromin, Andriy, Ji, Sung G, Weiss-Hung, Eli J, Sharman, Edward, Avilez, Alyssa P, Maki, Niki, Rafi, Masih A, Tian, Guilian, Akbari, Yama, Weiss, John H

“…Zn is an important contributor to ischemic brain injury, and recent studies support the hypothesis that mitochondria are key sites of its injurious effects. In…”
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