Search Results - "WEIR, S. J"

Distribution and abundance of Hector's dolphins (Cephalorhynchus hectori) off Kaikoura, New Zealand by Weir, JS, Sagnol, O

“…Boat-based surveys of Hector's dolphins (Cephalorhynchus hectori) were conducted throughout 2013 to evaluate their distribution and abundance off Kaikoura. We…”
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p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2 by Cloer, E. W., Siesser, P. F., Cousins, E. M., Goldfarb, D., Mowrey, D. D., Harrison, J. S., Weir, S. J., Dokholyan, N. V., Major, M. B.

“…Cancer-derived loss-of-function mutations in the KEAP1 tumor suppressor gene stabilize the NRF2 transcription factor, resulting in a prosurvival gene…”
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A mortality event in wrasse species (Labridae) associated with the presence of viral haemorrhagic septicaemia virus by Munro, E S, McIntosh, R E, Weir, S J, Noguera, P A, Sandilands, J M, Matejusova, I, Mayes, A S, Smith, R

“…Viral haemorrhagic septicaemia (VHS) is an infectious disease of farmed and wild fish and has an extensive host range in both freshwater and marine…”
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Single and multiple dose pharmacokinetics of rifapentine in man: Part II by KEUNG, A, ELLER, M. G, MCKENZIE, K. A, WEIR, S. J

“…OBJECTIVE: To characterize the pharmacokinetics of rifapentine following single, multiple, and intermittent doses.DESIGN: Twenty-three healthy male volunteers…”
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Enzyme induction observed in healthy volunteers after repeated administration of rifapentine and its lack of effect on steady-state rifapentine pharmacokinetics: Part I by KEUNG, A, REITH, K, ELLER, M. G, MCKENZIE, K. A, CHENG, L, WEIR, S. J

“…OBJECTIVE: To determine the effects of rifapentine on hepatic mixed function oxidase activity and to assess the effect of enzyme induction on the steady-state…”
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The repositioning of the anti-fungal agent ciclopirox olamine as a novel therapeutic agent for the treatment of haematologic malignancy by Weir, S. J., Patton, L., Castle, K., Rajewski, L., Kasper, J., Schimmer, A. D.

“…Summary What is known and Objective:  6‐Cyclohexyl‐1‐hydroxy‐4‐methyl‐2(1H)‐pyridone (ciclopirox) and specifically its olamine salt…”
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Pharmacokinetics of Rifapentine in Subjects Seropositive for the Human Immunodeficiency Virus: a Phase I Study by KEUNG, A. C.-F, OWENS, R. C, ELLER, M. G, WEIR, S. J, NICOLAU, D. P, NIGHTINGALE, C. H

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Percutaneous absorption of ketoprofen from different anatomical sites in man by SHAH, A. K, WEI, G, LANMAN, R. C, BHARGAVA, V. O, WEIR, S. J

“…The purpose of this study was to investigate the percutaneous absorption of ketoprofen applied topically to different anatomical sites on the body. The study…”
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Single-dose pharmacokinetics of rifapentine in elderly men by KEUNG, A. C. F, ELLER, M. G, WEIR, S. J

“…This study was undertaken to characterize the pharmacokinetic profiles of rifapentine and its active metabolite, 25-desacetlyl rifapentine, in elderly men…”
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Pharmacokinetics of Rifapentine in Patients with Varying Degrees of Hepatic Dysfunction by Keung, Anther C. F., Eller, Mark G., Weir, Scott J.

“…In this open‐label investigation, the pharmacokinetics of rifapentine and its active metabolite, 25‐desacetyl‐rifapentine, were characterized in patients with…”
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Using sentinel cages to estimate infestation pressure on salmonids from sea lice in Loch Shieldaig, Scotland by Pert, Campbell C., Fryer, Rob J., Cook, Paul, Kilburn, Rachel, McBeath, Sonia, McBeath, Alastair, Matejusova, Iveta, Urquhart, Katy, Weir, Sarah J., McCarthy, Una, Collins, Catherine, Amundrud, Trish, Bricknell, Ian R.

“…Sentinel Atlantic salmon, held in cages, were used to estimate the monthly infestation pressure of sea lice at 3 locations along a salmonid migration route in…”
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Pharmacokinetics of dolasetron with coadministration of cimetidine or rifampin in healthy subjects by DIMMITT, D. C, CRAMER, M. B, KEUNG, A, ARUMUGHAM, T, WEIR, S. J

“…Dolasetron is a selective 5-HT3 receptor antagonist. The purpose of this study was to determine the effect of cimetidine and rifampin on the steady-state…”
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Pharmacokinetics of oral and intravenous dolasetron mesylate in patients with renal impairment by DIMMITT, D. C, SHAH, A. K, ARUMUGHAM, T, CRAMER, M. B, HALSTENSON, C, HORTON, M, WEIR, S. J

“…In an open-label, randomized, two-way complete crossover study, the influence of renal impairment on the pharmacokinetics of dolasetron and its primary active…”
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Pharmacokinetics and pharmacodynamics of intravenous diltiazem in patients with atrial fibrillation or atrial flutter by DIAS, V. C, WEIR, S. J, ELLENBOGEN, K. A

“…Diltiazem, a calcium channel blocker, has been shown to be safe and effective in the treatment of patients in atrial fibrillation and/or atrial flutter…”
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Selection of Doses for Phase II Clinical Trials Based on Pharmacokinetic Variability Consideration by Yu, Dale K., Bhargava, Vijay O., Weir, Scott J.

“…Pharmacokinetic variability is an important component of the total variability in drug response, but Phase II dose‐response trials frequently are designed…”
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AN INVESTIGATION OF THE DOSE PROPORTIONALITY OF DEFLAZACORT PHARMACOKINETICS by Rao, Niranjan, Bhargava, Vijay O., Reynolds, Donald L., Eller, Mark G., Weir, Scott J.

“…The dose proportionality of deflazacort was assessed following single‐dose oral administration at doses of 3, 6, and 36 mg to 24 healthy young adult…”
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THE RELATIVE BIOAVAILABILITY OF TWO MARKETED CONTROLLED RELEASE DILTIAZEM DOSAGE FORMS AT STEADY STATE IN HEALTHY VOLUNTEERS by Lippert, C. L., Arumugham, T., Bhargava, V. O., Eller, M., Weir, S. J.

“…This study was conducted to determine the relative bioavailability of DilacorTM XR capsules compared to Cardizem® CD capsules at both low (180 mg d−1) and high…”
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Photobiomodulation Laser Therapy During Chemoradiation for Head and Neck Cancer: Effect on Mucositis, Weight Loss, and Feeding Tube Dependence by Krc, R.F., Singh, S., Weir, J.S.

“…The standard therapeutic approach for patients with head and neck cancer (HNC) often involves multi-modality therapy including surgery, radiation therapy (RT)…”
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Pharmacokinetics of 5-aminosalicylic acid from controlled-release capsules in man by Yu, D K, Morrill, B, Eichmeier, L S, Lanman, R C, Lanman, M B, Giesing, D H, Weir, S J

“…One gram single dose of Pentasa controlled-release capsules was administered to 24 healthy volunteers under fasting condition. Mean plasma 5-aminosalicylic…”
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Single-dose pharmacokinetics of rifapentine in women by Keung, A C, Eller, M G, Weir, S J

“…Gender can be an important variable in the absorption and disposition of some drugs. In this open-label study, 15 healthy, nonsmoking women received a single…”
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