Search Results - "WEINBERG, Frank D"
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Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors
Published in Cancer research (Chicago, Ill.) (15-12-2004)“…Mutations of the human type Ialpha regulatory subunit (RIalpha) of cyclic AMP-dependent protein kinase (PKA; PRKAR1A) lead to altered kinase activity, primary…”
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Cyclin-dependent kinase inhibitors for the treatment of lung cancer
Published in Expert opinion on pharmacotherapy (23-05-2020)“…Cyclin-dependent kinases (CDKs) are critical regulators of cell cycle progression in both normal and malignant cells, functioning through complex molecular…”
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Targeting IL22: a potential therapeutic approach for Kras mutant lung cancer?
Published in Translational lung cancer research (01-09-2018)Get full text
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Characterization of pneumonia and other factors leading to poorer survival across all age groups in patients with non-small cell lung cancer (NSCLC)
Published in Journal of thoracic disease (01-02-2021)“…Lung cancer death rates and incidence in both men and women have decreased over the past two decades. However, certain subsets of non-small cell lung cancer…”
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Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS
Published in The FASEB journal (01-03-2009)“…Senescence is a potential tumor-suppressing mechanism and a commonly used model of cellular aging. One current hypothesis to explain senescence, based in part…”
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Abstract 7366: Loss of STK11 suppresses lipid metabolism to attenuate KRAS-induced immunogenicity in patients with non-small cell lung cancer
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Background: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in the United States. Though NSCLC is genetically heterogeneous, as…”
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Abstract 176: Stearic acid induces pro-inflammatory macrophage response important for lung cancer development
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Background Survival is improved with early detection and treatment initiation in patients with lung cancer (LC) emphasizing the importance of tumor initiation…”
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Comprehensive sampling of the lung microbiome in early-stage non–small cell lung cancerCentral MessagePerspective
Published in JTCVS open (01-02-2024)“…Objectives: Data are scarce on whether the composition of the lung microbiome (extending from the nasopharynx to the peripheral lung tissue) varies according…”
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