Search Results - "WEILER, D. A"

Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes by Sur, Sanjiv, Glitz, Dohn G., Kita, Hirohito, Kujawa, Stephen M., Peterson, Ellen A., Weiler, Deborah A., Kephart, Gail M., Wagner, Jill M., George, Terry J., Gleich, Gerald J., Leiferman, Kristin M.

“…Eosinophil‐derived neurotoxin (EDN) and eosinophil cationic protein (ECP) are generally regarded as eosinophil‐specific proteins. We tested whether EDN and ECP…”
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A direct mechanical method for accurate and efficient adenoviral vector delivery to tissues by KHURANA, V. G, WEILER, D. A, WITT, T. A, SMITH, L. A, KLEPPE, L. S, PARISI, J. E, SIMARI, R. D, O'BRIEN, T, RUSSELL, S. J, KATUSIC, Z. S

“…We describe a mechanical method for delivery of adenoviral vector to the adventitial surface of arteries and to other tissues. Our goal was to characterize,…”
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Removal of bronchoalveolar cells augments the late eosinophilic response to segmental allergen challenge by Hunt, L. W., Gleich, G. J., Kita, H., Weiler, D. A., Schroeder, D. R., Vuk-Pavlovic, Z., Sur, S.

“…Background In patients with quiescent asthma, macrophages are the most prevalent cells recovered by bronchoalveolar lavage (BAL). Through activation via their…”
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Release of granule proteins from eosinophils cultured with IL-5 by Kita, H, Weiler, DA, Abu-Ghazaleh, R, Sanderson, CJ, Gleich, GJ

“…Eosinophils isolated from normal individuals were cultured in the presence of human rIL-5 (hrIL-5) for up to 14 days, and the effects of this exposure were…”
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Cytokine production at the site of disease in chronic eosinophilic pneumonitis by Kita, H, Sur, S, Hunt, L W, Edell, E S, Weiler, D A, Swanson, M C, Samsel, R W, Abrams, J S, Gleich, G J

“…Chronic eosinophilic pneumonitis (CEP) is characterized by longstanding respiratory symptoms accompanied by a massive pulmonary eosinophil infiltration. We…”
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Endotoxin contamination causes neutrophilia following pulmonary allergen challenge by Hunt, L W, Gleich, G J, Ohnishi, T, Weiler, D A, Mansfield, E S, Kita, H, Sur, S

“…Segmental bronchoprovocation (SBP) with allergen was used in an attempt to study eosinophils recruited to the airway 24 h after challenge. Unexpectedly, in the…”
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Adenovirus-Mediated Gene Transfer to Human Cerebral Arteries by Khurana, Vini G., Smith, Leslie A., Weiler, Deborah A., Springett, Margaret J., Parisi, Joseph E., Meyer, Fredric B., Marsh, W. Richard, O'Brien, Timothy, Katusic, Zvonimir S.

“…Gene therapy is being investigated as a putative treatment option for cardiovascular diseases, including cerebral vasospasm. Because there is presently no…”
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Purification of tryptase from a human mast cell line by Butterfield, J H, Weiler, D A, Hunt, L W, Wynn, S R, Roche, P C

“…The neutral protease tryptase has been isolated from a human mast cell line, HMC-1. The HMC-1 line was established from the peripheral blood of a patient with…”
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Allergen challenge in asthma: association of eosinophils and lymphocytes with interleukin-5 by Sur, S, Gleich, G J, Offord, K P, Swanson, M C, Ohnishi, T, Martin, L B, Wagner, J M, Weiler, D A, Hunt, L W

“…To test whether eosinophil recruitment after pulmonary allergen challenge is associated with interleukin (IL)-5 in patients with asthma, we performed segmental…”
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Immunofluorescent staining for mast cells in idiopathic pulmonary fibrosis: quantification and evidence for extracellular release of mast cell tryptase by Hunt, L W, Colby, T V, Weiler, D A, Sur, S, Butterfield, J H

“…In many diseases, retrospective analysis for determining the presence of mast cells has been difficult because of their loss of metachromatic staining…”
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Does IgE Bind to and Activate Eosinophils from Patients with Allergy? by Kita, Hirohito, Kaneko, Masayuki, Bartemes, Kathleen R, Weiler, Deborah A, Schimming, Andrew W, Reed, Charles E, Gleich, Gerald J

“…Human eosinophils have been reported to express both the mRNA and protein for the high affinity IgE receptor (FcepsilonRI); it is speculated that this receptor…”
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In vitro sensitivity of immature human mast cells to chemotherapeutic agents by Butterfield, J H, Weiler, D A

“…Cells from the human immature mast cell line, HMC-1, were tested for their sensitivity to 11 chemotherapeutic agents by changes in viability and incorporation…”
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Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes by Sur, S, Glitz, D G, Kita, H, Kujawa, S M, Peterson, E A, Weiler, D A, Kephart, G M, Wagner, J M, George, T J, Gleich, G J, Leiferman, K M

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Eosinophil-active cytokine from mononuclear cells cultured with L-tryptophan products: An unexpected consequence of endotoxin contamination by Kita, Hirohito, Mayeno, Arthur N., Weyand, Cornelia M., Goronzy, Jörg J., Weiler, Deborah A., Lundy, Steven K., Abrams, John S., Gleich, Gerald J.

“…Background: The eosinophilia-myalgia syndrome, caused by a contaminant or contaminants in epidemiologically implicated L-tryptophan products, is characterized…”
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A Novel and Highly Divergent Homolog of Human Eosinophil Granule Major Basic Protein by Plager, Douglas A., Loegering, David A., Weiler, Deborah A., Checkel, James L., Wagner, Jill M., Clarke, Nigel J., Naylor, Stephen, Page, Scott M., Thomas, Larry L., Akerblom, Ingrid, Cocks, Ben, Stuart, Susan, Gleich, Gerald J.

“…Eosinophils are important effector cells in defense against helminth infection and in allergic diseases. To identify novel eosinophil proteins, large scale…”
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Comparative Structure, Proximal Promoter Elements, and Chromosome Location of the Human Eosinophil Major Basic Protein Genes by Plager, Douglas A., Weiler, Deborah A., Loegering, David A., Johnson, William B., Haley, Linda, Eddy, Roger L., Shows, Thomas B., Gleich, Gerald J.

“…Human eosinophil major basic protein (MBP) is strongly implicated as a mediator of disease, especially bronchial asthma. We recently isolated a highly…”
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Differentiation of Human Embryonic Stem Cells to Dopaminergic Neurons in Serum‐Free Suspension Culture by Schulz, Thomas C., Noggle, Scott A., Palmarini, Gail M., Weiler, Deb A., Lyons, Ian G., Pensa, Kate A., Meedeniya, Adrian C.B., Davidson, Bruce P., Lambert, Nevin A., Condie, Brian G.

“…The use of human embryonic stem cells (hESCs) as a source of dopaminergic neurons for Parkinson's disease cell therapy will require the development of simple…”
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Eosinophil differentiation of human umbilical cord mononuclear cells and prolonged survival of mature eosinophils by murine EL-4 thymoma cell conditioned medium by Ten, R M, Butterfield, J H, Kita, H, Weiler, D A, Fischkoff, S, Ishizaka, T, Sanderson, C J, Gleich, G J

“…Umbilical cord mononuclear cells, HL-60 cells, HL-60 clones selected for eosinophil differentiation, and the eosinophil leukemia cell line EoL were tested for…”
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Karyotypic stability, genotyping, differentiation, feeder-free maintenance, and gene expression sampling in three human embryonic stem cell lines derived prior to August 9, 2001 by Brimble, Sandii N, Zeng, Xianmin, Weiler, Deborah A, Luo, Yongquan, Liu, Ying, Lyons, Ian G, Freed, William J, Robins, Allan J, Rao, Mahendra S, Schulz, Thomas C

“…The number of human embryonic stem cell (hESC) lines available to federally funded U.S. researchers is currently limited. Thus, determining their basic…”
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Directed neuronal differentiation of human embryonic stem cells by Schulz, Thomas C, Palmarini, Gail M, Noggle, Scott A, Weiler, Deborah A, Mitalipova, Maisam M, Condie, Brian G

“…We have developed a culture system for the efficient and directed differentiation of human embryonic stem cells (HESCs) to neural precursors and neurons.HESC…”
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