Search Results - "WEIDONG CHAI"

Glucagon-Like Peptide 1 Recruits Microvasculature and Increases Glucose Use in Muscle via a Nitric Oxide-Dependent Mechanism by Chai, Weidong, Dong, Zhenhua, Wang, Nasui, Wang, Wenhui, Tao, Lijian, Cao, Wenhong, Liu, Zhenqi

“…Glucagon-like peptide 1 (GLP-1) increases tissue glucose uptake and causes vasodilation independent of insulin. We examined the effect of GLP-1 on muscle…”
Get full text

Glucagon-Like Peptide 1 Recruits Muscle Microvasculature and Improves Insulin's Metabolic Action in the Presence of Insulin Resistance by WEIDONG CHAI, XINGXING ZHANG, BARRETT, Eugene J, ZHENQI LIU

“…Glucagon-like peptide 1 (GLP-1) acutely recruits muscle microvasculature, increases muscle delivery of insulin, and enhances muscle use of glucose, independent…”
Get full text

Protein kinase A mediates glucagon-like peptide 1-induced nitric oxide production and muscle microvascular recruitment by Dong, Zhenhua, Chai, Weidong, Wang, Wenhui, Zhao, Lina, Fu, Zhuo, Cao, Wenhong, Liu, Zhenqi

“…Glucagon-like peptide-1 (GLP-1) causes vasodilation and increases muscle glucose uptake independent of insulin. Recently, we have shown that GLP-1 recruits…”
Get more information

p38 Mitogen-Activated Protein Kinase Mediates Palmitate-Induced Apoptosis But Not Inhibitor of Nuclear Factor-κB Degradation in Human Coronary Artery Endothelial Cells by Chai, Weidong, Liu, Zhenqi

“…Plasma free fatty acids are elevated in patients with type 2 diabetes and contribute to the pathogenesis of insulin resistance and endothelial dysfunction. The…”
Get full text

GLP-1 at physiological concentrations recruits skeletal and cardiac muscle microvasculature in healthy humans by Subaran, Sharmila C, Sauder, Matthew A, Chai, Weidong, Jahn, Linda A, Fowler, Dale E, Aylor, Kevin W, Basu, Ananda, Liu, Zhenqi

“…Muscle microvascular surface area determines substrate and hormonal exchanges between plasma and muscle interstitium. GLP-1 (glucagon-like peptide-1) regulates…”
Get more information

Losartan increases muscle insulin delivery and rescues insulin's metabolic action during lipid infusion via microvascular recruitment by Wang, Nasui, Chai, Weidong, Zhao, Lina, Tao, Lijian, Cao, Wenhong, Liu, Zhenqi

“…Insulin delivery and transendothelial insulin transport are two discrete steps that limit muscle insulin action. Angiotensin II type 1 receptor (AT1R) blockade…”
Get more information

Inhibitory influence of Enterococcus faecium on the propagation of swine influenza A virus in vitro by Wang, Zhenya, Chai, Weidong, Burwinkel, Michael, Twardziok, Sven, Wrede, Paul, Palissa, Christiane, Esch, Bettina, Schmidt, Michael F G

“…The control of infectious diseases such as swine influenza viruses (SwIV) plays an important role in food production both from the animal health and from the…”
Get full text

Angiotensin II Type 1 and Type 2 Receptors Regulate Basal Skeletal Muscle Microvascular Volume and Glucose Use by Chai, Weidong, Wang, Wenhui, Liu, Jia, Barrett, Eugene J, Carey, Robert M, Cao, Wenhong, Liu, Zhenqi

“…Angiotensin II causes vasoconstriction via the type 1 receptor (AT1R) and vasodilatation through the type 2 receptor (AT2R). Both are expressed in muscle…”
Get full text

Antiviral effects of a probiotic Enterococcus faecium strain against transmissible gastroenteritis coronavirus by Chai, Weidong, Burwinkel, Michael, Wang, Zhenya, Palissa, Christiane, Esch, Bettina, Twardziok, Sven, Rieger, Juliane, Wrede, Paul, Schmidt, Michael F. G.

“…The enteropathogenic coronavirus transmissible gastroenteritis virus (TGEV) causes severe disease in young piglets. We have studied the protective effects of…”
Get full text

Salsalate Attenuates Free Fatty Acid-Induced Microvascular and Metabolic Insulin Resistance in Humans by Chai, Weidong, Liu, Jia, Jahn, Linda A, Fowler, Dale E, Barrett, Eugene J, Liu, Zhenqi

“…OBJECTIVE: Insulin recruits muscle microvasculature, thereby increasing endothelial exchange surface area. Free fatty acids (FFAs) cause insulin resistance by…”
Get full text

β-2 Spectrin Regulates Angiogenesis and Ischemic-Diabetic Wound Healing by Pomy, Benjamin, Chai, Weidong, Rao, Shuyun, Sidawy, Anton, Mishra, Lopa, Nguyen, Bao-Ngoc

Get full text

Insulin at Physiological Concentrations Selectively Activates Insulin But Not Insulin-Like Growth Factor I (IGF-I) or Insulin/IGF-I Hybrid Receptors in Endothelial Cells by Li, Guolian, Barrett, Eugene J, Wang, Hong, Chai, Weidong, Liu, Zhenqi

“…In muscle, physiologic hyperinsulinemia, presumably acting on endothelial cells (ECs), dilates arterioles and regulates both total blood flow and capillary…”
Get full text

Dietary Enterococcus faecium NCIMB 10415 and zinc oxide stimulate immune reactions to trivalent influenza vaccination in pigs but do not affect virological response upon challenge infection by Wang, Zhenya, Burwinkel, Michael, Chai, Weidong, Lange, Elke, Blohm, Ulrike, Breithaupt, Angele, Hoffmann, Bernd, Twardziok, Sven, Rieger, Juliane, Janczyk, Pawel, Pieper, Robert, Osterrieder, Nikolaus

“…Swine influenza viruses (SIV) regularly cause significant disease in pigs worldwide. Since there is no causative treatment of SIV, we tested if probiotic…”
Get full text

Hyperglycemia in apolipoprotein E-deficient mouse strains with different atherosclerosis susceptibility by Li, Jing, Wang, Qian, Chai, Weidong, Chen, Mei-Hua, Liu, Zhenqi, Shi, Weibin

“…Type 2 diabetes mellitus (T2DM) is associated with an increased risk of atherosclerotic vascular disease, but it is unknown whether the other way around is…”
Get full text

Regulation of muscle microcirculation in health and diabetes by Liu, Zhenqi, Ko, Seung-Hyun, Chai, Weidong, Cao, Wenhong

“…Insulin increases microvascular perfusion and substrate exchange surface area in muscle, which is pivotal for hormone action and substrate exchange, by…”
Get full text

Spread from the Sink to the Patient: In Situ Study Using Green Fluorescent Protein (GFP)-Expressing Escherichia coli To Model Bacterial Dispersion from Hand-Washing Sink-Trap Reservoirs by Kotay, Shireen, Chai, Weidong, Guilford, William, Barry, Katie, Mathers, Amy J

“…There have been an increasing number of reports implicating as often carrying genes of drug resistance from colonized sink traps to vulnerable hospitalized…”
Get full text

Metformin prevents endothelial oxidative stress and microvascular insulin resistance during obesity development in male rats by Liu, Jia, Aylor, Kevin W, Chai, Weidong, Barrett, Eugene J, Liu, Zhenqi

“…Insulin increases muscle microvascular perfusion, which contributes to its metabolic action in muscle, but this action is impaired in obesity. Metformin…”
Get more information

Efficacy of two porcine reproductive and respiratory syndrome (PRRS) modified-live virus (MLV) vaccines against heterologous NADC30-like PRRS virus challenge by Chai, Weidong, Liu, Zhicheng, Sun, Zhi, Su, Liangke, Zhang, Chunhong, Huang, Lv

“…•The NADC-30 like v2016/ZJ/09-03 used in this study was a moderately virulent PRRSV.•The VR2332 vaccine reduced the percentage of viremic pigs as well as gross…”
Get full text

Angiotensin II receptors modulate muscle microvascular and metabolic responses to insulin in vivo by Chai, Weidong, Wang, Wenhui, Dong, Zhenhua, Cao, Wenhong, Liu, Zhenqi

“…Angiotensin (ANG) II interacts with insulin-signaling pathways to regulate insulin sensitivity. The type 1 (AT(1)R) and type 2 (AT(2)R) receptors reciprocally…”
Get full text

Liraglutide prevents microvascular insulin resistance and preserves muscle capillary density in high-fat diet-fed rats by Chai, Weidong, Fu, Zhuo, Aylor, Kevin W, Barrett, Eugene J, Liu, Zhenqi

“…Muscle microvasculature critically regulates endothelial exchange surface area to facilitate transendothelial delivery of insulin, nutrients, and oxygen to…”
Get more information