Search Results - "WEIDANG LI"

Peptide Vaccine: Progress and Challenges by Li, Weidang, Joshi, Medha D, Singhania, Smita, Ramsey, Kyle H, Murthy, Ashlesh K

“…Conventional vaccine strategies have been highly efficacious for several decades in reducing mortality and morbidity due to infectious diseases. The bane of…”
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Designing an experimental method for assessing biocompatibility of circuit coatings using biomarkers for platelet activation during cardiopulmonary bypass by Sancheti, Meghal, Rentschler, Mitchell, Bolch, Charlotte, Li, Weidang, Necco, Katelyn, Rath, Thomas, Esfandiarei, Mitra, Darban, Nathaniel

“…Cardiopulmonary bypass is an essential component of cardiothoracic surgeries. However, significant complications such as systemic inflammatory response…”
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Tumor Necrosis Factor Alpha Production from CD8⁺ T Cells Mediates Oviduct Pathological Sequelae following Primary Genital Chlamydia muridarum Infection by Murthy, Ashlesh K, Li, Weidang, Chaganty, Bharat K.R, Kamalakaran, Sangamithra, Guentzel, M. Neal, Seshu, J, Forsthuber, Thomas G, Zhong, Guangming, Arulanandam, Bernard P

“…The immunopathogenesis of Chlamydia trachomatis-induced oviduct pathological sequelae is not well understood. Mice genetically deficient in perforin…”
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Can 10 000 Healthy Steps a Day Slow Aortic Root Dilation in Pediatric Patients With Marfan Syndrome? by Selamet Tierney, Elif Seda, Chung, Sukyung, Stauffer, Katie Jo, Brabender, Jerrid, Collins, 2nd, Ronnie Thomad, Folk, Robert, Li, Weidang, Murthy, Ashlesh K, Murphy, Daniel Jerome, Esfandiarei, Mitra

“…Background Stiffer aortas are associated with a faster rate of aortic root (AoR) dilation and higher risk of aortic dissection in patients with Marfan…”
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Maternal Dietary Deficiency in Choline Reduced Levels of MMP-2 Levels in Blood and Brain Tissue of Male Offspring Mice by Esfandiarei, Mitra, Strash, Shawn G U, Covaleski, Amanda, Ille, Sharadyn, Li, Weidang, Jadavji, Nafisa M

“…Ischemic stroke is one of the leading causes of disability and death globally, with a rising incidence in younger age groups. It is well known that maternal…”
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Vaccination with the defined chlamydial secreted protein CPAF induces robust protection against female infertility following repeated genital chlamydial challenge by Murthy, Ashlesh K, Li, Weidang, Guentzel, M. Neal, Zhong, Guangming, Arulanandam, Bernard P

“…Abstract We previously have shown the efficacy of recombinant (r) chlamydial protease-like activity factor (CPAF) vaccination against hydrosalpinx development…”
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A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice by Li, Weidang, Murthy, Ashlesh K, Lanka, Gopala Krishna, Chetty, Senthilnath L, Yu, Jieh-Juen, Chambers, James P, Zhong, Guangming, Forsthuber, Thomas G, Guentzel, M. Neal, Arulanandam, Bernard P

“…Highlights • HLA-DR4 restricted T cell epitopes of CPAF were mapped. • CPAF epitope fusion protein protects against genital and pulmonary chlamydial challenge…”
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Perforin- and Granzyme-Mediated Cytotoxic Effector Functions Are Essential for Protection against Francisella tularensis following Vaccination by the Defined F. tularensis subsp. novicida ΔfopC Vaccine Strain by Sanapala, Shilpa, Yu, Jieh-Juen, Murthy, Ashlesh K, Li, Weidang, Guentzel, M Neal, Chambers, James P, Klose, Karl E, Arulanandam, Bernard P

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunization with a Combination of Integral Chlamydial Antigens and a Defined Secreted Protein Induces Robust Immunity against Genital Chlamydial Challenge by Li, Weidang, Murthy, Ashlesh K, Guentzel, M Neal, Chambers, James P, Forsthuber, Thomas G, Seshu, J, Zhong, Guangming, Arulanandam, Bernard P

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Heat denatured enzymatically inactive recombinant chlamydial protease-like activity factor induces robust protective immunity against genital chlamydial challenge by Chaganty, Bharat K.R, Murthy, Ashlesh K, Evani, Shankar J, Li, Weidang, Guentzel, M. Neal, Chambers, James P, Zhong, Guangming, Arulanandam, Bernard P

“…Abstract We have shown previously that vaccination with recombinant chlamydial protease-like activity factor (rCPAF) plus interleukin-12 as an adjuvant induces…”
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Induction of Cross-Serovar Protection against Genital Chlamydial Infection by a Targeted Multisubunit Vaccination Approach by Li, Weidang, Guentzel, M Neal, Seshu, J, Zhong, Guangming, Murthy, Ashlesh K, Arulanandam, Bernard P

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Chlamydia -Specific CD8+ T cells Enhance Neutrophil Infiltration into Chlamydia -Infected Female Mouse Genital Tract by Li, weidang, Ramsey, Kyle H., Murthy, Ashlesh K.

“…Abstract We recently demonstrated that Chlamydia-specific TNF-α producing and TNF receptor 2 bearing CD8+ T cells mediate chlamydial pathogenesis in the mouse…”
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Antigen-Specific CD4 T cells Protect Against Reproductive Pathology by Subverting Chlamydia -specific CD8 T cell Response by Li, Weidang, Warda, Katerina, Moy, Lindsay N, Musunuri, Tarakarama, Bui, Nhi, Wright-McAfee, Erika, Murthy, Ashlesh K.

“…Abstract We have demonstrated previously that CD4 T cells are protective whereas CD8 T cells cause reproductive pathology following genital chlamydial…”
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Protective anti-chlamydial vaccine regimen-induced CD4+ T cell response mediates early inhibition of pathogenic CD8+ T cell response following genital challenge by Murthy, Ashlesh K, Wright-McAfee, Erika, Warda, Katerina, Moy, Lindsay N, Bui, Nhi, Musunuri, Tarakarama, Manam, Srikanth, Chako, Clemence Z, Ramsey, Kyle H, Li, Weidang

“…Abstract We have demonstrated previously that TNF-α-producing CD8+ T cells mediate chlamydial pathogenesis, likely in an antigen (Ag)-specific fashion. Here we…”
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Antigen-specific CD8 T cell response following genital chlamydial challenge is a predictive biomarker of vaccine efficacy in protection against reproductive tract pathology by Murthy, Ashlesh K, Warda, Katerina, Moy, Lindsay, Musunuri, Tarakarama, Bui, Nhi, Wright-McAfee, Erika, Ramsey, Kyle H, Li, Weidang

“…Abstract TNF-α producing antigen (Ag)-specific CD8 T cells induce upper genital tract (UGT) pathology following primary C. muridarum infection; therefore, we…”
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The contribution of Chlamydia‐specific CD8+ T cells to upper genital tract pathology by Vlcek, Kelly R, Li, Weidang, Manam, Srikanth, Zanotti, Brian, Nicholson, Bruce J, Ramsey, Kyle H, Murthy, Ashlesh K

“…Genital chlamydial infections lead to severe upper reproductive tract pathology in a subset of untreated women. We demonstrated previously that tumor necrosis…”
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Tissue Specific Overexpression of Human Heat Shock Protein 70 in Mouse Oviduct Epithelium Reduces Chlamydia Induced Immunopathology by Murthy, Ashlesh K., Keeler, Kelly Rae, Do, Jennifer, Seetharaman, Aravind, Ramsey, Kyle H., Ciancio, Mae, Li, weidang

“…Abstract Chlamydia trachomatis genital infections lead to severe immunopathological consequences in the upper genital tract (UGT), including pelvic…”
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Immunopathogenesis of Chlamydial Infections by Murthy, Ashlesh K, Li, Weidang, Ramsey, Kyle H

“…Chlamydial infections lead to a number of clinically relevant diseases and induce significant morbidity in human populations. It is generally understood that…”
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Tumor Necrosis Factor (TNF) Receptor Superfamily Member 1b on CD8⁺ T Cells and TNF Receptor Superfamily Member 1a on Non-CD8⁺ T Cells Contribute Significantly to Upper Genital Tract Pathology Following Chlamydial Infection by Manam, Srikanth, Thomas, Joshua D., Li, Weidang, Maladore, Allison, Schripsema, Justin H., Ramsey, Kyle H., Murthy, Ashlesh K.

“…Background. We demonstrated previously that tumor necrosis factor α (TNF-α)-producing Chlamydia-specific CD8⁺ T cells cause oviduct pathological sequelae…”
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Intranasal immunization with recombinant chlamydial protease‐like activity factor attenuates atherosclerotic pathology following Chlamydia pneumoniae infection in mice by Li, Weidang, Gudipaty, Pareesha, Li, Chuxi, Henderson, Kyle K, Ramsey, Kyle H, Murthy, Ashlesh K

“…We have shown previously that intranasal vaccination with recombinant chlamydial protease‐like activity factor (rCPAF: antigen) and interleukin‐12 (IL‐12) as…”
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