Search Results - "WEI-GANG FANG"

P2X7 mediates ATP-driven invasiveness in prostate cancer cells by Qiu, Ying, Li, Wei-Hua, Zhang, Hong-Quan, Liu, Yan, Tian, Xin-Xia, Fang, Wei-Gang

“…The ATP-gated P2X7 has been shown to play an important role in invasiveness and metastasis of some tumors. However, the possible links and underlying…”
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Extracellular ATP promotes angiogenesis and adhesion of TNBC cells to endothelial cells via upregulation of CTGF by Zhou, Yan‐Ting, Yu, Yu‐Qing, Yang, Hui, Yang, Han, Huo, Yan‐Fei, Huang, Yang, Tian, Xin‐Xia, Fang, Wei‐Gang

“…Our previous works have indicated that extracellular ATP is an important prometastasis factor. However, the molecular mechanism involved needs to be further…”
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ATP‐P2Y2‐β‐catenin axis promotes cell invasion in breast cancer cells by Zhang, Jiang‐Lan, Liu, Ying, Yang, Hui, Zhang, Hong‐Quan, Tian, Xin‐Xia, Fang, Wei‐Gang

“…Extracellular adenosine 5′‐triphosphate (ATP), secreted by living cancer cells or released by necrotic tumor cells, plays an important role in tumor invasion…”
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Extracellular ATP promotes breast cancer invasion and epithelial‐mesenchymal transition via hypoxia‐inducible factor 2α signaling by Yang, Hui, Geng, Yue‐Hang, Wang, Peng, Zhou, Yan‐Ting, Yang, Han, Huo, Yan‐Fei, Zhang, Hong‐Quan, Li, Yan, He, Hui‐Ying, Tian, Xin‐Xia, Fang, Wei‐Gang

“…Extracellular ATP has been shown to play an important role in invasion and the epithelial‐mesenchymal transition (EMT) process in breast cancer; however, the…”
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Extracellular ATP promotes breast cancer invasion and chemoresistance via SOX9 signaling by Yang, Hui, Geng, Yue-Hang, Wang, Peng, Yang, Han, Zhou, Yan-Ting, Zhang, Hong-Quan, He, Hui-Ying, Fang, Wei-Gang, Tian, Xin-Xia

“…Our previous research demonstrated that extracellular adenosine 5′-triphosphate (ATP) could promote breast cancer cell invasion. However, the impact of…”
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P2Y2 Receptor and EGFR Cooperate to Promote Prostate Cancer Cell Invasion via ERK1/2 Pathway by Li, Wei-Hua, Qiu, Ying, Zhang, Hong-Quan, Tian, Xin-Xia, Fang, Wei-Gang

“…As one member of G protein-coupled P2Y receptors, P2Y2 receptor can be equally activated by extracellular ATP and UTP. Our previous studies have proved that…”
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Extracellular ATP promotes breast cancer chemoresistance via HIF-1α signaling by Yang, Hui, Geng, Yue-Hang, Wang, Peng, Zhang, Hong-Quan, Fang, Wei-Gang, Tian, Xin-Xia

“…We have previously demonstrated that extracellular adenosine 5'-triphosphate (ATP) promotes breast cancer cell chemoresistance. However, the underlying…”
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Dysregulation in nucleic acid‐sensing pathway genes is associated with cancer patients’ prognosis by Yan‐Fei, Huo, Han, Yang, Yan‐Ting, Zhou, Hui, Yang, Yu‐Qing, Yu, Ipsita, Panda, Hui‐Ying, He, Wei‐Gang, Fang, Xin‐Xia, Tian

“…The innate immune system, the first line of defense against pathogens, is activated by nucleic acids from microbial invaders that are recognized by nucleic…”
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Extracellular ATP drives breast cancer cell migration and metastasis via S100A4 production by cancer cells and fibroblasts by Liu, Ying, Geng, Yue-Hang, Yang, Hui, Yang, Han, Zhou, Yan-Ting, Zhang, Hong-Quan, Tian, Xin-Xia, Fang, Wei-Gang

“…Our previous work has demonstrated that extracellular ATP is an important pro-invasive factor, and in this study, we tapped into a possible mechanism involved…”
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Association study of germline variants in CCNB1 and CDK1 with breast cancer susceptibility, progression, and survival among Chinese Han women by Li, Yan, Chen, Yi-Lin, Xie, Yun-Tao, Zheng, Li-Yuan, Han, Ji-Yuan, Wang, Hui, Tian, Xin-Xia, Fang, Wei-Gang

“…The CCNB1 and CDK1 genes encode the proteins of CyclinB1 and CDK1 respectively, which interact with each other and are involved in cell cycle regulation,…”
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Association of Genetic Polymorphisms in CDH1 and CTNNB1 with Breast Cancer Susceptibility and Patients' Prognosis among Chinese Han Women by Jia, Yu-Mian, Xie, Yun-Tao, Wang, Ya-Jun, Han, Ji-Yuan, Tian, Xin-Xia, Fang, Wei-Gang

“…This study aims to investigate whether the germline variants in CDH1 and CTNNB1 would affect breast cancer susceptibility and patients' prognosis among Chinese…”
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Yiqifumai injection and its main ingredients attenuate lipopolysaccharide‐induced cerebrovascular hyperpermeability through a multi‐pathway mode by Li, Dan‐Tong, Sun, Kai, Huang, Ping, Pan, Chun‐Shui, Yan, Li, Ayan, Ayididaer, Liu, Yu‐Ying, Fan, Jing‐Yu, Fang, Wei‐Gang, Han, Jing‐Yan

“…Objective Yiqifumai injection is a compound Chinese medicine used to treat microcirculatory disturbance‐related diseases clinically. Our previous study proved…”
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Genetic Polymorphisms of TGFB1, TGFBR1, SNAI1 and TWIST1 Are Associated with Endometrial Cancer Susceptibility in Chinese Han Women by Yang, Li, Wang, Ya-Jun, Zheng, Li-Yuan, Jia, Yu-Mian, Chen, Yi-Lin, Chen, Lan, Liu, Dong-Ge, Li, Xiang-Hong, Guo, Hong-Yan, Sun, Ying-Li, Tian, Xin-Xia, Fang, Wei-Gang

“…Endometrial cancer (EC) is a complex disease involving multiple gene-gene and gene-environment interactions. TGF-β signaling plays pivotal roles in EC…”
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Quantification of alternative splicing variants of human telomerase reverse transcriptase and correlations with telomerase activity in lung cancer by Liu, Yan, Wu, Bing-quan, Zhong, Hao-hao, Tian, Xin-xia, Fang, Wei-gang

“…Telomerase plays important roles in the development and progression of malignant tumors, and its activity is primarily determined by transcriptional regulation…”
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CLIC4, ERp29, and Smac/DIABLO Derived from Metastatic Cancer Stem-like Cells Stratify Prognostic Risks of Colorectal Cancer by DENG, Yong-Jian, NA TANG, WANG, Ya-Nan, LIANG, Yao-Ze, BIAN, Xiu-Wu, FANG, Wei-Gang, DING, Yan-Qing, CHAO LIU, ZHANG, Jiang-Yu, AN, Sheng-Li, PENG, Yin-Li, MA, Li-Li, LI, Guang-Qiu, QIANG JIANG, HU, Chun-Ting

“…Cancer stem-like cells have been well accepted to be involved in recurrence and metastasis of cancers, but the prognostic potential of biomarkers integrating…”
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Treatment with Corticosteroid and/or Immunosuppressive Agents before Surgery can Effectively Improve the Surgical Outcome in Patients with Takayasu's Arteritis by Zheng, Tie, Zhu, Shuai, Ou, Jia-Fu, Fang, Wei-Gang, Qiao, Zhi-Yu, Qi, Rui-Dong, Chen, Li, Chen, Lei, Li, Cheng-Nan, Pan, Li-Li, Zhu, Qing, Chen, Dong, Sun, Xue-Jun, Zhu, Jun-Ming

“…Objective: To analyze the clinical outcome of corticosteroid and/or immunosuppressive treatment preoperatively in patients with Takayasu's arteritis. Patients…”
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Acute Aortic Dissection in Young Adult Patients: Clinical Characteristics, Management, and Perioperative Outcomes by Zhu, Shuai, Zheng, Tie, Qiao, Zhi-Yu, Chen, Li, Ou, Jia-Fu, Fang, Wei-Gang, Li, Cheng-Nan, Chen, Lei, Ma, Wei-Guo, Zheng, Jun, Liu, Yong-Min, Sun, Li-Zhong, Sun, Xue-Jun, Zhu, Jun-Ming

“…Background: Acute aorta dissection (AD) is a fatal emergency, however, studies addressing the clinical characteristics, management, and outcome of acute AD in…”
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Genetic polymorphisms in AURKA and BRCA1 are associated with breast cancer susceptibility in a Chinese Han population by Ruan, Yuan, Song, Ai-Ping, Wang, Hui, Xie, Yun-Tao, Han, Ji-Yuan, Sajdik, Constantin, Tian, Xin-Xia, Fang, Wei-Gang

“…Centrosome defects can result in aneuploidy and genomic instability, and have important implications for breast cancer development. The Aurora‐A and BRCA1…”
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Association of germline variation in CCNE1 and CDK2 with breast cancer risk, progression and survival among Chinese Han women by Han, Ji-Yuan, Wang, Hui, Xie, Yun-Tao, Li, Yan, Zheng, Li-Yuan, Ruan, Yuan, Song, Ai-Ping, Tian, Xin-Xia, Fang, Wei-Gang

“…Somatic alterations of cyclin-dependent kinase 2 (CDK2)-cyclin E complex have been shown to contribute to breast cancer (BC) development and progression. This…”
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Extracellular ATP enhances in vitro invasion of prostate cancer cells by activating Rho GTPase and upregulating MMPs expression by Zhang, Yang, Gong, Li-hua, Zhang, Hong-quan, Du, Qiang, You, Jiang-feng, Tian, Xin-xia, Fang, Wei-gang

“…Abstract We previously found that in addition to anti-proliferation function, extracellular ATP had a pro-invasion effect on prostate cancer cells, and…”
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