Search Results - "WEEKS, Mark E"

Proteomic Analysis of Kveim Reagent Identifies Targets of Cellular Immunity in Sarcoidosis by Eberhardt, Christian, Thillai, Muhunthan, Parker, Robert, Siddiqui, Nazneen, Potiphar, Lee, Goldin, Rob, Timms, John F, Wells, Athol U, Kon, Onn M, Wickremasinghe, Melissa, Mitchell, Donald, Weeks, Mark E, Lalvani, Ajit

“…Kveim-reagent (Kv) skin testing was a historical method of diagnosing sarcoidosis. Intradermal injection of treated sarcoidosis spleen tissue resulted in a…”
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Intra-Tumor Genetic Heterogeneity in Wilms Tumor: Clonal Evolution and Clinical Implications by Cresswell, George D., Apps, John R., Chagtai, Tasnim, Mifsud, Borbala, Bentley, Christopher C., Maschietto, Mariana, Popov, Sergey D., Weeks, Mark E., Olsen, Øystein E., Sebire, Neil J., Pritchard-Jones, Kathy, Luscombe, Nicholas M., Williams, Richard D., Mifsud, William

“…The evolution of pediatric solid tumors is poorly understood. There is conflicting evidence of intra-tumor genetic homogeneity vs. heterogeneity (ITGH) in a…”
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Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease by Spanos, Christos, Maldonado, Elaina M, Fisher, Ciarán P, Leenutaphong, Petchpailin, Oviedo-Orta, Ernesto, Windridge, David, Salguero, Francisco J, Bermúdez-Fajardo, Alexandra, Weeks, Mark E, Evans, Caroline, Corfe, Bernard M, Rabbani, Naila, Thornalley, Paul J, Miller, Michael H, Wang, Huan, Dillon, John F, Quaglia, Alberto, Dhawan, Anil, Fitzpatrick, Emer, Moore, J Bernadette

“…Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. However, its molecular pathogenesis is incompletely characterized and…”
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The role of S100p in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D by WHITEMAN, Hannah J, WEEKS, Mark E, DOWEN, Sally E, BARRY, Sayka, TIMMS, John F, LEMOINE, Nicholas R, CRNOGORAC-JURCEVIC, Tatjana

“…Up-regulation of S100P, a member of the S100 calcium-binding protein family, is an early molecular event in the development of pancreatic cancer and it is…”
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Sarcoidosis and tuberculosis cytokine profiles: indistinguishable in bronchoalveolar lavage but different in blood by Thillai, Muhunthan, Eberhardt, Christian, Lewin, Alex M, Potiphar, Lee, Hingley-Wilson, Suzie, Sridhar, Saranya, Macintyre, Jonathan, Kon, Onn Min, Wickremasinghe, Melissa, Wells, Athol, Weeks, Mark E, Mitchell, Donald, Lalvani, Ajit

“…The clinical, radiological and pathological similarities between sarcoidosis and tuberculosis can make disease differentiation challenging. A complicating…”
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Correction to: Proteomic identification and characterization of hepatic glyoxalase 1 dysregulation in non-alcoholic fatty liver disease by Spanos, Christos, Maldonado, Elaina M, Fisher, Ciarán P, Leenutaphong, Petchpailin, Oviedo-Orta, Ernesto, Windridge, David, Salguero, Francisco J, Bermúdez-Fajardo, Alexandra, Weeks, Mark E, Evans, Caroline, Corfe, Bernard M, Rabbani, Naila, Thornalley, Paul J, Miller, Michael H, Wang, Huan, Dillon, John F, Quaglia, Alberto, Dhawan, Anil, Fitzpatrick, Emer, Moore, J Bernadette

“…[This corrects the article DOI: 10.1186/s12953-018-0131-y.]…”
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AGR2 Is a Novel Surface Antigen That Promotes the Dissemination of Pancreatic Cancer Cells through Regulation of Cathepsins B and D by DUMARTIN, Laurent, WHITEMAN, Hannah J, BRENNAN, Caroline, LEMOINE, Nicholas R, CRNOGORAC-JURCEVIC, Tatjana, WEEKS, Mark E, HARIHARAN, Deepak, DMITROVIC, Branko, LACOBUZIO-DONAHUE, Christine A, BRENTNALL, Teresa A, BRONNER, Mary P, FEAKINS, Roger M, TIMMS, John F

“…Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers largely due to disseminated disease at the time of presentation. Here, we…”
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AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting by Liu, Alvin Y, Kanan, Adelle D, Radon, Tomasz P, Shah, Siama, Weeks, Mark E, Foster, Julie M, Sosabowski, Jane K, Dumartin, Laurent, Crnogorac-Jurcevic, Tatjana

“…Anterior gradient 2 (AGR2), a protein disulfide isomerase, shows two subcellular localizations: intracellular (iAGR2) and extracellular (eAGR2). In healthy…”
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Proteomics and Systems Biology: Current and Future Applications in the Nutritional Sciences by Moore, J. Bernadette, Weeks, Mark E.

“…In the last decade, advances in genomics, proteomics, and metabolomics have yielded large-scale datasets that have driven an interest in global analyses, with…”
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A parallel proteomic and metabolomic analysis of the hydrogen peroxide- and Sty1p-dependent stress response in Schizosaccharomyces pombe by Weeks, Mark E., Sinclair, John, Butt, Amna, Chung, Yuen-Li, Worthington, Jessica L., Wilkinson, Caroline R. M., Griffiths, John, Jones, Nic, Waterfield, Michael D., Timms, John F.

“…Using an integrated approach incorporating proteomics, metabolomics and published mRNA data, we have investigated the effects of hydrogen peroxide on wild type…”
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Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase‐σ by Alete, Daniel E., Weeks, Mark E., Hovanession, Ara G., Hawadle, Muhamed, Stoker, Andrew W.

“…Reversible tyrosine phosphorylation, catalyzed by receptor tyrosine kinases and receptor tyrosine phosphatases, plays an essential part in cell signaling…”
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Application of proteomics in cancer gene profiling: two-dimensional difference in gel electrophoresis (2D-DIGE) by Hariharan, Deepak, Weeks, Mark E, Crnogorac-Jurcevic, Tatjana

“…In the post-genomic era, proteomic strategies are at the forefront of cancer research. By studying the complement of all expressed genes, proteomics aims to…”
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Urinary proteome profiling using 2D-DIGE and LC-MS/MS by Weeks, Mark E

“…Proteomic methodologies have been at the forefront of cancer research for several years. The use of proteomic strategies to study all expressed genes aims to…”
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Analysis of the urine proteome in patients with pancreatic ductal adenocarcinoma by Weeks, Mark E., Hariharan, Deepak, Petronijevic, Ljiljana, Radon, Tomasz P., Whiteman, Hannah J., Kocher, Hemant M., Timms, John F., Lemoine, Nicholas R., Crnogorac-Jurcevic, Tatjana

“…Pancreatic ductal adenocarcinoma (PDAC) accounts for over 213 000 deaths worldwide each year, largely due to late diagnosis. One of the risk factors for the…”
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Mass spectrometry identification of circulating alpha-1-B glycoprotein, increased in aged female C57BL/6 mice by Stehle, John R., Weeks, Mark E., Lin, Kai, Willingham, Mark C., Hicks, Amy M., Timms, John F., Cui, Zheng

“…In this study, we surveyed the profiles of mouse circulating proteins by 2-dimensional SDS-PAGE in different strains, sexes and ages. Among visible protein…”
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Stress-induced changes in the Schizosaccharomyces pombe proteome using two-dimensional difference gel electrophoresis, mass spectrometry and a novel integrated robotics platform by Weeks, Mark E., Sinclair, John, Jacob, Richard J., Saxton, Malcolm J., Kirby, Susan, Jones, James, Waterfield, Michael D., Cramer, Rainer, Timms, John F.

“…Robotic and manual methods have been used to obtain identification of significantly changing proteins regulated when Schizosaccharomyces pombe is exposed to…”
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Global changes in gene expression observed at the transition from growth to stationary phase in Listeria monocytogenes ScottA batch culture by Weeks, Mark E., James, David C., Robinson, Gary K., Smales, C. Mark

“…Listeria monocytogenes is a food‐borne Gram‐positive bacterium that is responsible for a variety of infections (worldwide) annually. The organism is able to…”
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A parallel proteomic and metabolomic analysis of the hydrogen peroxide- and Sty1p-dependent stress response inSchizosaccharomyces pombe by Weeks, Mark E., Sinclair, John, Butt, Amna, Chung, Yuen-Li, Worthington, Jessica L., Wilkinson, Caroline R. M., Griffiths, John, Jones, Nic, Waterfield, Michael D., Timms, John F.

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Residual Lung Abnormalities after COVID-19 Hospitalization: Interim Analysis of the UKILD Post-COVID-19 Study by Stewart, Iain, Jacob, Joseph, George, Peter M, Molyneaux, Philip L, Porter, Joanna C, Allen, Richard J, Aslani, Shahab, Baillie, J Kenneth, Barratt, Shaney L, Beirne, Paul, Bianchi, Stephen M, Blaikley, John F, Chalmers, James D, Chambers, Rachel C, Chadhuri, Nazia, Coleman, Christopher, Collier, Guilhem, Denneny, Emma K, Docherty, Annemarie, Elneima, Omer, Evans, Rachael A, Fabbri, Laura, Gibbons, Michael A, Gleeson, Fergus V, Gooptu, Bibek, Greening, Neil J, Guio, Beatriz Guillen, Hall, Ian P, Hanley, Neil A, Harris, Victoria, Harrison, Ewen M, Heightman, Melissa, Hillman, Toby E, Horsley, Alex, Houchen-Wolloff, Linzy, Jarrold, Ian, Johnson, Simon R, Jones, Mark G, Khan, Fasihul, Lawson, Rod, Leavy, Olivia, Lone, Nazir, Marks, Michael, McAuley, Hamish, Mehta, Puja, Parekh, Dhruv, Hanley, Karen Piper, Platé, Manuela, Pearl, John, Poinasamy, Krisnah, Quint, Jennifer K, Raman, Betty, Richardson, Matthew, Rivera-Ortega, Pilar, Saunders, Laura, Saunders, Ruth, Semple, Malcolm G, Sereno, Marco, Shikotra, Aarti, Simpson, A John, Singapuri, Amisha, Smith, David J F, Spears, Mark, Spencer, Lisa G, Stanel, Stefan, Thickett, David R, Thompson, A A Roger, Thorpe, Mathew, Walsh, Simon L F, Walker, Samantha, Weatherley, Nicholas David, Weeks, Mark E, Wild, Jim M, Wootton, Dan G, Brightling, Chris E, Ho, Ling-Pei, Wain, Louise V, Jenkins, Gisli R

“…Shared symptoms and genetic architecture between coronavirus disease (COVID-19) and lung fibrosis suggest severe acute respiratory syndrome coronavirus 2…”
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Proteomics and Systems Biology: Current and Future Applications in the Nutritional Sciences1 by Moore, J. Bernadette, Weeks, Mark E.

“…In the last decade, advances in genomics, proteomics, and metabolomics have yielded large-scale datasets that have driven an interest in global analyses, with…”
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