Search Results - "WEEKS, D. D"

Aminoacyl-tRNA Synthetases as Valuable Targets for Antimicrobial Drug Discovery by Pang, Luping, Weeks, Stephen D, Van Aerschot, Arthur

“…Aminoacyl-tRNA synthetases (aaRSs) catalyze the esterification of tRNA with a cognate amino acid and are essential enzymes in all three kingdoms of life. Due…”
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Embedded 3D Printing of Multimaterial Polymer Lattices via Graph‐Based Print Path Planning by Weeks, Robert D., Truby, Ryan L., Uzel, Sebastien G. M., Lewis, Jennifer A.

“…Recent advances in computational design and 3D printing enable the fabrication of polymer lattices with high strength‐to‐weight ratio and tailored mechanics…”
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Long-ranged contributions to solvation free energies from theory and short-ranged models by Remsing, Richard C., Liu, Shule, Weeks, John D.

“…Long-standing problems associated with long-ranged electrostatic interactions have plagued theory and simulation alike. Traditional lattice sum (Ewald-like)…”
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TET2-mutant clonal hematopoiesis and risk of gout by Agrawal, Mridul, Niroula, Abhishek, Cunin, Pierre, McConkey, Marie, Shkolnik, Veronica, Kim, Peter G., Wong, Waihay J., Weeks, Lachelle D., Lin, Amy E., Miller, Peter G., Gibson, Christopher J., Sekar, Aswin, Schaefer, Inga-Marie, Neuberg, Donna, Stone, Richard M., Bick, Alexander G., Uddin, Md Mesbah, Griffin, Gabriel K., Jaiswal, Siddhartha, Natarajan, Pradeep, Nigrovic, Peter A., Rao, Deepak A., Ebert, Benjamin L.

“…Gout is a common inflammatory arthritis caused by precipitation of monosodium urate (MSU) crystals in individuals with hyperuricemia. Acute flares are…”
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Dissecting Hydrophobic Hydration and Association by Remsing, Richard C, Weeks, John D

“…We use appropriately defined short-ranged reference models of liquid water to clarify the different roles local hydrogen bonding, van der Waals attractions,…”
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Effect of Ar(3p 5 4p; 2p)+M → Ar(3p 5 4s; 1s)+M branching ratio on optically pumped rare gas laser performance by Emmons, D J, Weeks, D E

“…Optically pumped rare gas laser performance is analyzed as a function of the Ar(3p 4p; 2p) + M → Ar(3p 4s; 1s) + M branching ratios. Due to the uncertainty in…”
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Oxytocin: still the optimal prophylactic despite soaring rates of haemorrhage at birth by Weeks, AD

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What should we believe when systematic reviews disagree? by Weeks, AD

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Does balloon tamponade really make postpartum haemorrhage worse? by Weeks, AD

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Embedded 3D Printing of Multimaterial Polymer Lattices via Graph‐Based Print Path Planning by Weeks, Robert D., Truby, Ryan L., Uzel, Sebastien G. M., Lewis, Jennifer A.

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Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins by Vanmeert, Michiel, Razzokov, Jamoliddin, Mirza, Muhammad Usman, Weeks, Stephen D, Schepers, Guy, Bogaerts, Annemie, Rozenski, Jef, Froeyen, Mathy, Herdewijn, Piet, Pinheiro, Vitor B, Lescrinier, Eveline

“…Xenobiotic nucleic acids (XNA) are nucleic acid analogues not present in nature that can be used for the storage of genetic information. In vivo XNA…”
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Controlling nanoparticle delivery in magnetic nanoparticle hyperthermia for cancer treatment: experimental study in agarose gel by Salloum, M, Ma, R H, Weeks, D, Zhu, L

“…In magnetic nanoparticle hyperthermia for cancer treatment, controlling the heat distribution and temperature elevations is an immense challenge in clinical…”
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A missense variant in CREBRF, rs373863828, is associated with fat-free mass, not fat mass in Samoan infants by Arslanian, K. J., Fidow, U. T., Atanoa, T., Unasa-Apelu, F., Naseri, T., Wetzel, A. I., Pomer, A., Duckham, R. L., McGarvey, S. T., Strayer, J. A., Kershaw, E. E., Weeks, D. E., Hawley, N. L.

“…Background/objectives: In Samoa, where 80% of the adult population is living with obesity, understanding the determinants of adiposity and growth during…”
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Acetonitrile on Silica Surfaces and at Its Liquid−Vapor Interface: Structural Correlations and Collective Dynamics by Hu, Zhonghan, Weeks, John D

“…Solvent structure and dynamics of acetonitrile at its liquid−vapor (LV) interface and at the acetonitrile−silica (LS) interface are studied by means of…”
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Uracil-DNA glycosylase expression determines human lung cancer cell sensitivity to pemetrexed by Weeks, Lachelle D, Fu, Pingfu, Gerson, Stanton L

“…Uracil misincorporation into DNA is a consequence of pemetrexed inhibition of thymidylate synthase. The base excision repair (BER) enzyme uracil-DNA…”
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Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies by Pang, Luping, Weeks, Stephen D., Juhás, Martin, Strelkov, Sergei V., Zitko, Jan, Van Aerschot, Arthur

“…Human cytosolic prolyl-tRNA synthetase (HcProRS) catalyses the formation of the prolyl-tRNAPro, playing an important role in protein synthesis. Inhibition of…”
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The in-vitro effect of famotidine on SARS-CoV-2 proteases and virus replication by Loffredo, Madeline, Lucero, Hector, Chen, Da-Yuan, O’Connell, Aoife, Bergqvist, Simon, Munawar, Ahmad, Bandara, Asanga, De Graef, Steff, Weeks, Stephen D., Douam, Florian, Saeed, Mohsan, Munawar, Ali H.

“…The lack of coronavirus-specific antiviral drugs has instigated multiple drug repurposing studies to redirect previously approved medicines for the treatment…”
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MALT1 auto-proteolysis is essential for NF-κB-dependent gene transcription in activated lymphocytes by Baens, Mathijs, Bonsignore, Luca, Somers, Riet, Vanderheydt, Charlotte, Weeks, Stephen D, Gunnarsson, Jenny, Nilsson, Ewa, Roth, Robert G, Thome, Margot, Marynen, Peter

“…Mucosa-associated lymphoid tissue 1 (MALT1) controls antigen receptor-mediated signalling to nuclear factor κB (NF-κB) through both its adaptor and protease…”
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Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity by Sillen, Machteld, Weeks, Stephen D, Strelkov, Sergei V, Declerck, Paul J

“…Plasminogen activator inhibitor-1 (PAI-1) is the main physiological inhibitor of tissue-type (tPA) and urokinase-type (uPA) plasminogen activators (PAs). Apart…”
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Operative Management of Ulnar Collateral Ligament Insufficiency in Adolescent Athletes by Jones, Kristofer J., Dines, Joshua S., Rebolledo, Brian J., Weeks, Kenneth D., Williams, Riley J., Dines, David M., Altchek, David W.

“…Background: The incidence of ulnar collateral ligament (UCL) injuries of the elbow has increased in adolescents over the past decade because of widespread…”
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