Search Results - "WEBSTER, Linda"
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1
Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients
Published in Science translational medicine (25-10-2017)“…Pulmonary arterial hypertension (PAH) is a progressive vascular disease with a high mortality rate. It is characterized by an occlusive vascular remodeling due…”
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Journal Article -
2
nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted
Published in Proceedings of the National Academy of Sciences - PNAS (03-07-2007)“…In pulmonary arterial hypertension (PAH), antiapoptotic, proliferative, and inflammatory diatheses converge to create an obstructive vasculopathy. A selective…”
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Journal Article -
3
Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility
Published in Circulation (New York, N.Y.) (17-07-2007)“…Sildenafil was recently approved for the treatment of pulmonary arterial hypertension. The beneficial effects of phosphodiesterase type 5 (PDE5) inhibitors in…”
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4
SNPs for Genes Encoding the Mitochondrial Proteins Sirtuin3 and Uncoupling Protein 2 Are Associated With Disease Severity, Type 2 Diabetes, and Outcomes in Patients With Pulmonary Arterial Hypertension and This Is Recapitulated in a New Mouse Model Lacking Both Genes
Published in Journal of the American Heart Association (07-12-2021)“…Background Isolated loss-of-function single nucleotide polymorphisms (SNPs) for (a mitochondrial deacetylase) and (an atypical uncoupling protein enabling…”
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5
Testing for Sexually Transmitted Diseases in U.S. Public Health Laboratories in 2004
Published in Sexually transmitted diseases (01-01-2007)“…Objective: Appropriate laboratory testing practices are a critical part of sexually transmitted disease (STD) control. Goal: The goal of this study was to…”
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6
Laboratory Tests Used in U.S. Public Health Laboratories for Sexually Transmitted Diseases, 2000
Published in Sexually transmitted diseases (01-05-2004)“…Background and Objectives: Public health laboratories are a critical component of sexually transmitted disease (STD) control in the United States. Goal: The…”
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Journal Article -
7
Chinese Parental Involvement and Children's School Readiness: The Moderating Role of Parenting Style
Published in Early education and development (17-02-2020)“…Research Findings: This study examined the moderating role of parenting style in the relations between different dimensions of parental involvement and their…”
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Journal Article -
8
Aggressive Drive Derivatives in the Rorschachs of Maltreated Children and Adolescents: Latent Structure and Clinical Correlates
Published in Journal of personality assessment (02-11-2017)“…Psychological assessment can play an important role in informing the intervention process with child and adolescent victims of maltreatment. This study…”
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Journal Article -
9
The risk of serious cardiac arrhythmias among cisapride users in the United Kingdom and Canada
Published in The American journal of medicine (01-10-1999)“…Serious, although rare, ventricular arrhythmias and deaths have been reported in patients taking cisapride monohydrate. Without quantification of the risk…”
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10
Sirtuin 3 Deficiency Is Associated with Inhibited Mitochondrial Function and Pulmonary Arterial Hypertension in Rodents and Humans
Published in Cell metabolism (04-11-2014)“…Suppression of mitochondrial function promoting proliferation and apoptosis suppression has been described in the pulmonary arteries and extrapulmonary tissues…”
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11
Sequential Latent Structure Analysis of Segregated System Material in the Doll Play of Maltreated Children
Published in Journal of child & adolescent trauma (01-09-2018)“…A range of assessment methodologies pertaining to attachment in children have been developed and validated during the past decades. The present study examined…”
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12
A multidimensional examination of Chinese family involvement in early childhood education: Validation of the Chinese version of the Family Involvement Questionnaire
Published in International journal of early years education (01-01-2021)“…This study preliminarily examined the multiple dimensions of Chinese family involvement in early childhood education across demographic variables through a…”
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Journal Article -
13
Reducing electronic health record-related burnout in providers through a personalized efficiency improvement program
Published in Journal of the American Medical Informatics Association : JAMIA (23-04-2021)“…To give providers a better understanding of how to use the electronic health record (EHR), improve efficiency, and reduce burnout. All ambulatory providers…”
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14
The Effects of a Lag Schedule on Mand Variability on Children With Autism Who Use a Selection Based Communication System
Published 01-01-2024“…The purpose of this study is to examine if Lag schedules can increase variability in children who use a selection-based communication system. For this study,…”
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Dissertation -
15
Attention and Executive Functions as Mediators of Attachment and Behavior Problems
Published in Social development (Oxford, England) (01-08-2016)“…The purpose of this study was to provide a more comprehensive understanding of the relation between early parent‐child interactions and subsequent behavior…”
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16
Use of the Adult Attachment Projective Picture System in an Assessment of an Adolescent in Foster Care
Published in Journal of personality assessment (01-09-2011)“…Child maltreatment has been associated with a host of negative outcomes including impaired social relationships (Rogosch, Cicchetti, & Aber, 1995), depression…”
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Journal Article -
17
Sleep-Disordered Breathing and Chronic Opioid Therapy
Published in Pain medicine (Malden, Mass.) (01-05-2008)“…ABSTRACT Objective. To assess the relation between medications prescribed for chronic pain and sleep apnea. Design. An observational study of chronic pain…”
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Abstract 13575: Lack of Both Mitochondrial Proteins Sirt3 and Ucp2 in Mice Recapitulates Many Critical Features of Human Pulmonary Arterial Hypertension (PAH), Including Inflammatory Plexogenic Lesions, Supporting the Metabolic Theory of PAH
Published in Circulation (New York, N.Y.) (17-11-2020)“…Loss-of function SNPs for Sirt3 (a mitochondrial deacetylase) and Ucp2 (an atypical uncoupling protein enabling mitochondrial calcium entry) have been…”
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Use of sildenafil for safe improvement of erectile function and quality of life in men with New York Heart Association classes II and III congestive heart failure: a prospective, placebo-controlled, double-blind crossover trial
Published in Archives of internal medicine (1960) (08-03-2004)“…Erectile dysfunction (ED) is common in patients with congestive heart failure (CHF) and is often associated with symptoms of depression. Although sildenafil…”
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20
A Description of Cultural Humility as Perceived by Nursing Faculty in Baccalaureate Nursing Education
Published 01-01-2019“…In diverse populations, health inequities can exist, thereby contributing to health disparities. A lack of knowledge regarding unfamiliar cultural patterns and…”
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Dissertation