Search Results - "WEBER, Kim S. C"

RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium by VON HUNDELSHAUSEN, Philipp, WEBER, Kim S. C, YUQING HUO, PROUDFOOT, Amanda E. I, NELSON, Peter J, LEY, Klaus, WEBER, Christian

“…Circulating platelets and chemoattractant proteins, such as the CC chemokine RANTES, contribute to the activation and interaction of monocytes and endothelium…”
Get full text

Differential chemokine receptor expression and function in human monocyte subpopulations by Weber, Christian, Belge, Kai‐Uwe, Hundelshausen, Philipp, Draude, Georg, Steppich, Birgit, Mack, Mathias, Frankenberger, Marion, Weber, Kim S. C., Ziegler‐Heitbrock, H. W Löms

“…The subset of human blood monocytes expressing low levels of CD14 and high levels of CD16 (CD14+CD16+) exhibits features resembling mature tissue macrophages…”
Get full text

Expression of CCR2 by Endothelial Cells: Implications for MCP-1 Mediated Wound Injury Repair and In Vivo Inflammatory Activation of Endothelium by Weber, Kim S.C, Nelson, Peter J, Gröne, Hermann-Joseph, Weber, Christian

“…Endothelial cell proliferation and migration may play a central role in angiogenesis, wound healing, and atherosclerosis. Although CXC chemokines can act on…”
Get full text

Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium by Baltus, Thomas, Weber, Kim S.C., Johnson, Zoë, Proudfoot, Amanda E.I., Weber, Christian

“…Chemokines control inflammatory leukocyte recruitment. The propensity of chemokines such as CC chemokine ligand 5 (CCL5)/RANTES (regulated on activation,…”
Get full text

Combinatorial Model of Chemokine Involvement in Glomerular Monocyte Recruitment: Role of CXC Chemokine Receptor 2 in Infiltration During Nephrotoxic Nephritis by Zernecke, Alma, Weber, Kim S. C, Erwig, Lars P, Kluth, David C, Schroppel, Bernd, Rees, Andrew J, Weber, Christian

“…A sequential model involving chemokines has been proposed for leukocyte extravasation into areas of inflammation; however, site-specific aspects remain to be…”
Get full text

Sialylation of ICAM-2 on platelets impairs adhesion of leukocytes via LFA-1 and DC-SIGN by Weber, Kim S C, Alon, Ronen, Klickstein, Lloyd B

“…Intercellular adhesion molecule (ICAM)-2 is highly expressed on platelets and endothelium and is a counter-receptor for the leukocyte integrin, lymphocyte…”
Get full text

Specialized roles of the chemokine receptors CCR1 and CCR5 in the recruitment of monocytes and TH1-like/CD45RO+ T cells by WEBER, Christian, WEBER, Kim S. C, KLIER, Christiane, GU, Songhai, WANK, Rudolf, HORUK, Richard, NELSON, Peter J

“…Chemokines and their receptors control the emigration of leukocytes during inflammation. The role of the RANTES (regulated on activation normal T-cell…”
Get full text

JAM-1 is a ligand of the β2 integrin LFA-1 involved in transendothelial migration of leukocytes by Ostermann, Georg, Weber, Kim S. C, Zernecke, Alma, Schroder, Andreas, Weber, Christian

Get full text

Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions by Weber, C, Erl, W, Weber, K S, Weber, P C

“…The integrin heterodimer CDllb/CD18 (alphaMbeta2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen,…”
Get more information

Differential immobilization and hierarchical involvement of chemokines in monocyte arrest and transmigration on inflamed endothelium in shear flow by Weber, Kim S. C., von Hundelshausen, Philipp, Clark‐Lewis, Ian, Weber, Peter C., Weber, Christian

“…Monocyte extravasation into areas of inflammation involves sequential interactions of multiple adhesion molecules. However, differential contribution of…”
Get full text

Met‐RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment by Gröne, Hermann‐Josef, Weber, Christian, Weber, Kim S. C., Gröne, Elisabeth F., Rabelink, Ton, Klier, Christiane M., Wells, Timothy N. C., Proudfoot, Amanda E., Schlondorff, Detlef, Nelson, Peter J.

“…ABSTRACTChemokines are thought to contribute to the cellular infiltrate characteristic of renal transplant rejection. We show that Met‐RANTES, a chemokine…”
Get full text

A Dominant Jurkat T Cell Mutation That Inhibits LFA-1-Mediated Cell Adhesion Is Associated with Increased Cell Growth by Cherry, Lisa K, Weber, Kim S. C, Klickstein, Lloyd B

“…LFA-1 exists in a low avidity state on resting leukocytes and is believed to adopt a high avidity state when the cells are exposed to a stimulus. Current…”
Get full text

JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes by Ostermann, Georg, Weber, Kim S C, Zernecke, Alma, Schröder, Andreas, Weber, Christian

“…Inflammatory recruitment of leukocytes is governed by dynamic interactions between integrins and endothelial immunoglobulin superfamily (IgSF) proteins. We…”
Get full text

Nuclear Factor-kappa B Regulates Induction of Apoptosis and Inhibitor of Apoptosis Protein-1 Expression in Vascular Smooth Muscle Cells by Erl, Wolfgang, Hansson, Goran K, de Martin, Rainer, Draude, Georg, Weber, Kim S.C, Weber, Christian

“…Apoptosis is important in normal development as well as in diseases such as atherosclerosis. However, the regulation of apoptosis is still not completely…”
Get full text

A Non-peptide Functional Antagonist of the CCR1 Chemokine Receptor Is Effective in Rat Heart Transplant Rejection by Horuk, Richard, Clayberger, Carol, Krensky, Alan M., Wang, Zhaohui, Gröne, Hermann-Josef, Weber, Christian, Weber, Kim S.C., Nelson, Peter J., May, Karen, Rosser, Mary, Dunning, Laura, Liang, Meina, Buckman, Brad, Ghannam, Ameen, Ng, Howard P., Islam, Imadul, Bauman, John G., Wei, Guo-Ping, Monahan, Sean, Xu, Wei, Snider, R. Michael, Morrissey, Michael M., Hesselgesser, Joseph, Perez, H. Daniel

“…Chemokines like RANTES appear to play a role in organ transplant rejection. Because RANTES is a potent agonist for the chemokine receptor CCR1, we examined…”
Get full text

Chemokine‐induced monocyte transmigration requires cdc42‐mediated cytoskeletal changes by Weber, Kim S. C., Klickstein, Lloyd B., Weber, Peter C., Weber, Christian

“…The ras‐related small GTPases of the rho family coordinate the assembly of complex cytoskeletal structures crucial for cell motility and polarization. Cdc42…”
Get full text

Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTES‐dependent firm adhesion of leukocytes by Mack, Matthias, Pfirstinger, Jochen, Weber, Christian, Weber, Kim S.C., Nelson, Peter J., Rupp, Tamara, Maletz, Konstantin, Brühl, Hilke, Schlöndorff, Detlef

“…The sequestration of chemokines on the surface of microvascular endothelium is an early event in the selective recruitment of leukocytes. The sequestration and…”
Get full text

JAM-1 is a ligand of the β 2 integrin LFA-1 involved in transendothelial migration of leukocytes by Weber, Christian, Ostermann, Georg, Weber, Kim S. C, Zernecke, Alma, Schröder, Andreas

Get full text

JAM-1 is a ligand of the [beta]2 integrin LFA-1 involved in transendothelial migration of leukocytes by Ostermann, Georg, Weber, Kim S C, Zernecke, Alma, Schröder, Andreas, Weber, Christian

“…Inflammatory recruitment of leukocytes is governed by dynamic interactions between integrins and endothelial immunoglobulin superfamily (IgSF) proteins. We…”
Get full text

Transient increase of monocyte adhesion after a single dose of simvastatin by Erl, Wolfgang, Weber, Kim S.C, Weber, Peter C, Weber, Christian

“…Beneficial effects of HMG-CoA reductase inhibitors, such as simvastatin have been attributed to lipid lowering and cholesterol-independent mechanisms, for…”
Get full text