Search Results - "WAUGH, J M"

Increased free fat-graft survival with the long-term, local delivery of insulin, insulin-like growth factor-I, and basic fibroblast growth factor by PLGA/PEG microspheres by YUKSEL, E, WEINFELD, A. B, CLEEK, R, WAMSLEY, S, JENSEN, J, BOUTROS, S, WAUGH, J. M, SHENAQ, S. M, SPIRA, M

“…The present investigation evaluates the effects of long-term, local delivery of insulin, insulin-like growth factor-1 (IGF-1), and basic fibroblast growth…”
Get full text

Thrombomodulin overexpression to limit neointima formation by WAUGH, J. M, LI-HAWKINS, J, DAKE, M. D, WOO, S. L. C, YUKSEL, E, KUO, M. D, CIFRA, P. N, HILFIKER, P. R, GESKE, R, CHAWLA, M, THOMAS, J, SHENAQ, S. M

“…BACKGROUND-These studies were initiated to confirm that high-level thrombomodulin overexpression is sufficient to limit neointima formation after mechanical…”
Get full text

Local Overexpression of Thrombomodulin for In Vivo Prevention of Arterial Thrombosis in a Rabbit Model by Waugh, J.M, Yuksel, E, Li, J, Kuo, NA, Kattash, M, Saxena, R, Geske, R, Thung, S.N, Shenaq, NA, Woo, S.L.C

“…Endothelial thrombomodulin plays a critical role in hemostasis by binding thrombin and subsequently converting protein C to its active form, a powerful…”
Get full text

Gene Therapy to Promote Thromboresistance: Local Overexpression of Tissue Plasminogen Activator to Prevent Arterial Thrombosis in an in vivo Rabbit Model by Waugh, J. M., Kattash, M., Li, J., Yuksel, E., Kuo, M. D., Lussier, M., Weinfeld, A. B., Saxena, R., Rabinovsky, E. D., Thung, S., Woo, S. L. C., Shenaq, S. M.

“…Tissue-type plasminogen activator (tPA) catalyzes the rate-limiting initial step in the fibrinolytic cascade. Systemic infusion of tPA has become the standard…”
Get full text

De Novo Adipose Tissue Generation through Long-Term, Local Delivery of Insulin and Insulin-Like Growth Factor-1 by PLGA/PEG Microspheres in an in Vivo Rat Model: A Novel Concept and Capability by Yuksel, Eser, Weinfeld, Adam B, Cleek, Robert, Waugh, Jacob M, Jensen, John, Boutros, Sean, Shenaq, Saleh M, Spira, Melvin

“…This study was undertaken to characterize the duration of long-term growth factor delivery by poly(lactic-co-glycolicacid)-polyethylene glycol (PLGA/PEG)…”
Get full text

Augmentation of adipofascial flaps using the long-term local delivery of insulin and insulin-like growth factor-1 by YUKSEL, E, WEINFELD, A. B, CLEEK, R, JENSEN, J, WAMSLEY, S, WAUGH, J. M, SPIRA, M, SHENAQ, S

“…The adipofascial flaps currently described in the literature frequently lack the volume requirements for reconstructive goals. In this study, the authors…”
Get full text

Vascular endothelial growth factor enhances atherosclerotic plaque progression by Dake, Michael D, Celletti, Francesca L, Waugh, Jacob M, Amabile, Philippe G, Brendolan, Andrea, Hilfiker, Paul R

“…Vascular endothelial growth factor (VEGF) can promote angiogenesis but may also exert certain effects to alter the rate of atherosclerotic plaque development…”
Get full text

Vascular gene therapy by Thomas, J W, Kuo, M D, Chawla, M, Waugh, J M, Yuksel, E, Wright, K C, Gerrity, P M, Shenaq, S M, Whigham, C J, Fisher, R G

“…Gene therapy is an exciting frontier in medicine today. Radiologists will be involved in tracking the effects of these new therapies through imaging. Vascular…”
Get more information

High-efficiency endovascular gene delivery via therapeutic ultrasound by Amabile, Philippe G, Waugh, Jacob M, Lewis, Thomas N, Elkins, Christopher J, Janas, Wolfgang, Dake, Michael D

“…OBJECTIVES We studied enhancement of local gene delivery to the arterial wall by using an endovascular catheter ultrasound (US). BACKGROUND Ultrasound exposure…”
Get full text

Philosophy's Surrender to Poetry (The End of an Ancient Rivalry) by Waugh, J. M. B.

Get full text

Local gene delivery: arterial thrombosis model for endothelial cell-targeted thrombolytic gene therapy research by Shenaq, S M, Kattash, M M, Weinfeld, A B, Waugh, J M, Yüksel, E, Yüksel, M, Gura, D H

“…The authors describe a rabbit arterial thrombosis model that employs vessel division followed by microsurgical anastomosis and transluminal sutures, to…”
Get more information

Art and Morality: The End of an Ancient Rivalry? by BEIL WAUGH, J. M

Get full text

Perivascular release of insulin-like growth factor-1 limits neointima formation in the balloon-injured artery by redirecting smooth muscle cell migration by Wong, A H, Amabile, P G, Yuksel, E, Waugh, J M, Dake, M D

“…Insulin-like growth factor-1 (IGF-1) is a potent chemoattractant to vascular smooth muscle cells (SMCs). The authors hypothesize that perivascular release of…”
Get more information

Therapeutic elastase inhibition by alpha-1-antitrypsin gene transfer limits neointima formation in normal rabbits by Waugh, J M, Li-Hawkins, J, Yuksel, E, Cifra, P N, Amabile, P G, Hilfiker, P R, Geske, R S, Kuo, M D, Thomas, J W, Dake, M D, Woo, S L

“…Alpha-1-antitrypsin (AAT) is the major circulating elastase inhibitor. Deficiency of elastase inhibition leads to emphysema and vascular abnormalities…”
Get more information

Enhancement of neointima formation with tissue-type plasminogen activator by Hilfiker, Paul R., Waugh, Jacob M., Li-Hawkins, Jia J., Kuo, Michael D., Yuksel, Eser, Geske, Robert S., Cifra, Pamela N., Chawla, Muneesh, Weinfeld, Adam B., Thomas, John W., Shenaq, Saleh M., Dake, Michael D.

“…Purpose: Indirect evidence suggests that tissue plasminogen activator (tPA) either limits or does not alter restenosis. However, tPA enhances tumor…”
Get full text

The potential of in vivo vascular tissue engineering for the treatment of vascular thrombosis: A preliminary report by KUO, M. D, WAUGH, J. M, YUKSEL, E, WEINFELD, A. B, YUKSEL, M, DAKE, M. D

Get full text

Development of a platform to evaluate and limit in-stent restenosis by Elkins, C J, Waugh, J M, Amabile, P G, Minamiguchi, H, Uy, M, Sugimoto, K, Do, Y S, Ganaha, F, Razavi, M K, Dake, M D

“…The objective of this work was to develop a platform to evaluate and deliver putative therapeutic agents for in-stent restenosis. Arterial stenting is applied…”
Get more information

Resection of the head of the pancreas and duodenum; operative technic by WAUGH, J M

Get more information

Primary diverticula of the duodenum by WAUGH, J M, JOHNSTON, E V

Get full text

THE SURGICAL MANAGEMENT OF MULTIPLE POLYPOSIS by WAUGH, J M, HARP, R A, SPENCER, R J

Get full text