Search Results - "WATSON, Peter Y"

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    The glmS riboswitch integrates signals from activating and inhibitory metabolites in vivo by Fedor, Martha J, Watson, Peter Y

    Published in Nature structural & molecular biology (01-03-2011)
    “…Riboswitches are RNA elements that provide feedback regulation of metabolic genes upon ligand binding. The glmS riboswitch is also a ribozyme, self-cleaving…”
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    Journal Article
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    mRNA secondary structures fold sequentially but exchange rapidly in vivo by Mahen, Elisabeth M, Watson, Peter Y, Cottrell, Joseph W, Fedor, Martha J

    Published in PLoS biology (01-02-2010)
    “…RNAs adopt defined structures to perform biological activities, and conformational transitions among alternative structures are critical to virtually all…”
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    Journal Article
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    The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis by Watson, Peter Y, Fedor, Martha J

    Published in Nature chemical biology (01-12-2012)
    “…Riboswitches—RNA motifs that regulate gene expression in response to binding of specific ligands—have been identified for many small-molecule metabolites. An…”
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    Journal Article
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    A DEAD-box RNA helicase promotes thermodynamic equilibration of kinetically trapped RNA structures in vivo by Ruminski, Dana J, Watson, Peter Y, Mahen, Elisabeth M, Fedor, Martha J

    Published in RNA (Cambridge) (01-03-2016)
    “…RNAs must assemble into specific structures in order to carry out their biological functions, but in vitro RNA folding reactions produce multiple misfolded…”
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    Journal Article
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    Brief report: Resident and faculty perceptions of conflict of interest in medical education by WATSON, Peter Y, KHANDELWAL, Akshay K, MUSIAL, Joseph L, BUCKLEY, John D

    “…OBJECTIVE: To determine resident and faculty perceptions of the pharmaceutical industry’s influence on medical education.DESIGN, SETTING, AND PARTICIPANTS:…”
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    Journal Article
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    Determination of intracellular RNA folding rates using self-cleaving RNAs by Watson, Peter Y, Fedor, Martha J

    Published in Methods in enzymology (2009)
    “…We have developed a system that relies on RNA self-cleavage to report quantitatively on assembly of RNA structures in vivo. Self-cleaving RNA sequences are…”
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    Journal Article
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    Resident and Faculty Perceptions of Conflict of Interest in Medical Education by Watson, Peter Y., Khandelwal, Akshay K., Musial, Joseph L., Buckley, John D.

    “…Objective: To determine resident and faculty perceptions of the pharmaceutical industry's influence on medical education. Design, Setting, And Participants:…”
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    Journal Article
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    The working and learning environment for physicians in training in the US by Watson, Peter Y

    Published in BMJ (04-10-2003)
    “…Limits on resident work hours, with financial and staff support, are needed…”
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    Journal Article
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    Residents' Work Hours by Crausman, Robert S

    Published in The New England journal of medicine (13-02-2003)
    “…To the Editor: In his Health Policy Report on the debate over residents' work hours (Oct. 17 issue), 1 Steinbrook notes that “for teaching hospitals, the…”
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    Journal Article
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    CFTR: the nucleotide binding folds regulate the accessibility and stability of the activated state by Wilkinson, D J, Mansoura, M K, Watson, P Y, Smit, L S, Collins, F S, Dawson, D C

    Published in The Journal of general physiology (01-01-1996)
    “…The functional roles of the two nucleotide binding folds, NBF1 and NBF2, in the activation of the cystic fibrosis transmembrane conductance regulator (CFTR)…”
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    Journal Article
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    mRNA Secondary Structures Fold Sequentially But Exchange Rapidly In Vivo: e1000307 by Mahen, Elisabeth M, Watson, Peter Y, Cottrell, Joseph W, Fedor, Martha J

    Published in PLoS biology (01-02-2010)
    “…RNAs adopt defined structures to perform biological activities, and conformational transitions among alternative structures are critical to virtually all…”
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    Journal Article
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    Intracellular studies of ribozymes and riboswitches by Watson, Peter Y

    Published 01-01-2012
    “…This work explores the biological functions of structured RNAs in the living cell. RNA folding studies of the hairpin ribozyme, functional exploration of the…”
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    Dissertation
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    LACK OF CONCORDANCE BETWEEN REPORTED LUNG-CANCER RISK LEVELS AND OCCUPATION-SPECIFIC DIESEL-EXHAUST EXPOSURE by A. Valberg, Ann Y. Watson, Peter

    Published in Inhalation toxicology (2000)
    “…Some epidemiologic studies of occupational groups show associations between surrogates of diesel-exhaust exposure and increased lung cancer, but causality has…”
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    Journal Article
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