Search Results - "WATSON, Peter"

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates by Millard, Christopher J., Watson, Peter J., Celardo, Ivana, Gordiyenko, Yuliya, Cowley, Shaun M., Robinson, Carol V., Fairall, Louise, Schwabe, John W.R.

“…Class I histone deacetylases (HDAC1, HDAC2, and HDAC3) are recruited by cognate corepressor proteins into specific transcriptional repression complexes that…”
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Applying Machine Learning to Improve Simulations of a Chaotic Dynamical System Using Empirical Error Correction by Watson, Peter A. G.

“…Dynamical weather and climate prediction models underpin many studies of the Earth system and hold the promise of being able to make robust projections of…”
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Machine learning applications for weather and climate need greater focus on extremes by Watson, Peter A G

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Determination of absorbed dose to water from a miniature kilovoltage x-ray source using a parallel-plate ionization chamber by Watson, Peter G F, Popovic, Marija, Seuntjens, Jan

“…Electronic brachytherapy sources are widely accepted as alternatives to radionuclide-based systems. Yet, formal dosimetry standards for these devices to…”
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Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer by West, Nathan R, Milne, Katy, Truong, Pauline T, Macpherson, Nicol, Nelson, Brad H, Watson, Peter H

“…Infiltration of breast tumors by tumor-infiltrating lymphocytes (TIL) has been associated with sensitivity to anthracycline-based chemotherapy. However, it is…”
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Biospecimen Complexity-the Next Challenge for Cancer Research Biobanks? by Watson, Peter H

“…Biospecimens (e.g., tissues, bloods, fluids) are critical for translational cancer research to generate the necessary knowledge to guide implementation of…”
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An investigation into the INTRABEAM miniature x‐ray source dosimetry using ionization chamber and radiochromic film measurements by Watson, Peter G. F., Bekerat, Hamed, Papaconstadopoulos, Pavlos, Davis, Stephen, Seuntjens, Jan

“…Purpose Intraoperative radiotherapy using The INTRABEAM System (Carl Zeiss Meditec AG, Jena, Germany), a miniature low‐energy x‐ray source, has proven to be an…”
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Systematic analysis of immune infiltrates in high-grade serous ovarian cancer reveals CD20, FoxP3 and TIA-1 as positive prognostic factors by Milne, Katy, Köbel, Martin, Kalloger, Steven E, Barnes, Rebecca O, Gao, Dongxia, Gilks, C Blake, Watson, Peter H, Nelson, Brad H

“…Tumor-infiltrating T cells are associated with survival in epithelial ovarian cancer (EOC), but their functional status is poorly understood, especially…”
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Targeting Class I Histone Deacetylases in a “Complex” Environment by Millard, Christopher J, Watson, Peter J, Fairall, Louise, Schwabe, John W.R

“…Histone deacetylase (HDAC) inhibitors are proven anticancer therapeutics and have potential in the treatment of many other diseases including HIV infection,…”
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The role of the tropical West Pacific in the extreme Northern Hemisphere winter of 2013/2014 by Watson, Peter A. G., Weisheimer, Antje, Knight, Jeff R., Palmer, T. N.

“…In the 2013/2014 winter, the eastern U.S. was exceptionally cold, the Bering Strait region was exceptionally warm, California was in the midst of drought, and…”
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CD103 and Intratumoral Immune Response in Breast Cancer by Wang, Zhi-Qiang, Milne, Katy, Derocher, Heather, Webb, John R, Nelson, Brad H, Watson, Peter H

“…CD103 is expressed in several immune cell types but in the context of the intratumoral immune response may be most important as a marker of antigen-activated…”
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A Twenty-Year Follow-up Study of Trabeculectomy: Risk Factors and Outcomes by Landers, John, PhD, FRANZCO, Martin, Keith, MRCP, FRCOphth, Sarkies, Nicholas, FRCS, FRCOphth, Bourne, Rupert, MD, FRCOphth, Watson, Peter, FRCS, FRCOphth

“…Purpose This study was undertaken to determine the performance of trabeculectomy surgery over a 20-year period and examine the associations between outcome and…”
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Structure of HDAC3 bound to co-repressor and inositol tetraphosphate by Watson, Peter J., Fairall, Louise, Santos, Guilherme M., Schwabe, John W. R.

“…Histone deacetylase enzymes (HDACs) are emerging cancer drug targets. They regulate gene expression by removing acetyl groups from lysine residues in histone…”
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How Can Charities use Coaching to Develop Managers and Does the Charity Context Matter? by Peter Watson

“…Little research exists on coaching in charities. This article explores how coaching might support managers in the charity sector. Using an interpretivist…”
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A Data-Driven Decision Support Tool for Anticipating Tropical Storm Impacts to the United States Power Grid by Watson, Peter L., Pasqualini, Donatella, Anagnostou, Emmanouil

“…Power outages caused by tropical storms significantly impact the United States economy and citizens every year. If the impacts of these storms could be better…”
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Changes in Winter Temperature Extremes From Future Arctic Sea‐Ice Loss and Ocean Warming by Lo, Y. T. Eunice, Mitchell, Dann M., Watson, Peter A. G., Screen, James A.

“…Observed rapid Arctic warming and sea‐ice loss are likely to continue in the future, unless and after greenhouse gas emissions are reduced to net‐zero. Here,…”
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Evaluation of Dosimetry Formalisms in Intraoperative Radiation Therapy of Glioblastoma by Ayala Alvarez, David Santiago, Watson, Peter G.F., Popovic, Marija, Heng, Veng Jean, Evans, Michael D.C., Panet-Raymond, Valerie, Seuntjens, Jan

“…The intraoperative radiotherapy in newly diagnosed glioblastoma multiforme (INTRAGO) clinical trial assesses survival in patients with glioblastoma treated…”
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CD20+ Tumor-Infiltrating Lymphocytes Have an Atypical CD27― Memory Phenotype and Together with CD8+ T Cells Promote Favorable Prognosis in Ovarian Cancer by NIELSEN, Julie S, SAHOTA, Rob A, MILNE, Katy, KOST, Sara E, NESSLINGER, Nancy J, WATSON, Peter H, NELSON, Brad H

“…Tumor-infiltrating lymphocytes (TIL), in particular CD8(+) T cells and CD20(+) B cells, are strongly associated with survival in ovarian cancer and other…”
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Larger Spatial Footprint of Wintertime Total Precipitation Extremes in a Warmer Climate by Bevacqua, Emanuele, Shepherd, Theodore G., Watson, Peter A. G., Sparrow, Sarah, Wallom, David, Mitchell, Dann

“…The simultaneous occurrence of extremely wet winters at multiple locations in the same region can contribute to widespread flooding and associated…”
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Finite element analysis of feeding in red and gray squirrels (Sciurus vulgaris and Sciurus carolinensis) by Cox, Philip G, Watson, Peter J

“…Invasive gray squirrels (Sciurus carolinensis) have replaced the native red squirrel (Sciurus vulgaris) across much of Great Britain over the last century…”
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