Search Results - "WATHELET, Marc G"

Severe Acute Respiratory Syndrome Coronavirus Evades Antiviral Signaling: Role of nsp1 and Rational Design of an Attenuated Strain by Wathelet, Marc G, Orr, Melissa, Frieman, Matthew B, Baric, Ralph S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling by Jauregui, Andrew R, Savalia, Dhruti, Lowry, Virginia K, Farrell, Cara M, Wathelet, Marc G

“…An epidemic of Severe Acute Respiratory Syndrome (SARS) led to the identification of an associated coronavirus, SARS-CoV. This virus evades the host innate…”
Get full text

Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria by Mebratu, Yohannes A., Leyva-Baca, Ivan, Wathelet, Marc G., Lacey, Neal, Chand, Hitendra S., Choi, Augustine M. K., Tesfaigzi, Yohannes

“…Bik reduces hyperplastic epithelial cells by releasing calcium from endoplasmic reticulum stores and causing apoptosis, but the detailed mechanisms are not…”
Get full text

Interferon Regulatory Factor-7 Synergizes with Other Transcription Factors through Multiple Interactions with p300/CBP Coactivators by Yang, Hongmei, Lin, Charles H., Ma, Gang, Baffi, Michael O., Wathelet, Marc G.

“…Interferon regulatory factor (IRF)-7 is activated in response to virus infection and stimulates the transcription of a set of cellular genes involved in host…”
Get full text

New World Hantaviruses Activate IFNλ Production in Type I IFN-Deficient Vero E6 Cells by Prescott, Joseph, Hall, Pamela, Acuna-Retamar, Mariana, Ye, Chunyan, Wathelet, Marc G., Ebihara, Hideki, Feldmann, Heinz, Hjelle, Brian

“…Background Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS). These viruses induce a strong…”
Get full text

Hypoxia‐activated metabolic pathway stimulates phosphorylation of p300 and CBP in oxygen‐sensitive cells by Zakrzewska, Adriana, Schnell, Phillip O., Striet, Justin B., Hui, Anna, Robbins, Jennifer R., Petrovic, Milan, Conforti, Laura, Gozal, David, Wathelet, Marc G., Czyzyk‐Krzeska, Maria F.

“…Transcription co‐activators and histone acetyltransferases, p300 and cyclic AMP responsive element‐binding protein‐binding protein (CBP), participate in…”
Get full text

Implication of a Chromosome 15q15.2 Locus in Regulating UBR1 and Predisposing Smokers to MGMT Methylation in Lung by Leng, Shuguang, Wu, Guodong, Collins, Leonard B, Thomas, Cynthia L, Tellez, Carmen S, Jauregui, Andrew R, Picchi, Maria A, Zhang, Xiequn, Juri, Daniel E, Desai, Dhimant, Amin, Shantu G, Crowell, Richard E, Stidley, Christine A, Liu, Yushi, Swenberg, James A, Lin, Yong, Wathelet, Marc G, Gilliland, Frank D, Belinsky, Steven A

“…O(6)-Methylguanine-DNA methyltransferase (MGMT) is a DNA repair enzyme that protects cells from carcinogenic effects of alkylating agents; however, MGMT is…”
Get full text

Virus Infection Induces the Assembly of Coordinately Activated Transcription Factors on the IFN-β Enhancer In Vivo by Wathelet, Marc G, Lin, Charles H, Parekh, Bhavin S, Ronco, Lucienne V, Howley, Peter M, Maniatis, Tom

“…We have identified a virus-activated factor (VAF) that binds to a regulatory element shared by different virus-inducible genes. We provide evidence that VAF…”
Get full text

Syndecan-2 Exerts Antifibrotic Effects by Promoting Caveolin-1―mediated Transforming Growth Factor-β Receptor I Internalization and Inhibiting Transforming Growth Factor-β1 Signaling by YUANYUAN SHI, GOCHUICO, Bernadette R, GOODWIN, Andrew J, HASPEL, Jeffrey A, RYTER, Stefan W, BILLINGS, Eric M, KAMINSKI, Naftali, MORSE, Danielle, ROSAS, Ivan O, GUOYING YU, XIAOMENG TANG, OSORIO, Juan C, FERNANDEZ, Isis E, RISQUEZ, Cristobal F, PATEL, Avignat S, YING SHI, WATHELET, Marc G

“…Alveolar transforming growth factor (TGF)-β1 signaling and expression of TGF-β1 target genes are increased in patients with idiopathic pulmonary fibrosis (IPF)…”
Get full text

Expression Cloning of an Interferon-inducible 17-kDa Membrane Protein Implicated in the Control of Cell Growth (∗) by Deblandre, Gisèle A., Marinx, Olivier P., Evans, Sharon S., Majjaj, Samira, Leo, Oberdan, Caput, Daniel, Huez, Georges A., Wathelet, Marc G.

“…Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on (1)…”
Get full text

Mechanism for transcriptional synergy between interferon regulatory factor (IRF)‐3 and IRF‐7 in activation of the interferon‐β gene promoter by Yang, Hongmei, Ma, Gang, Lin, Charles H., Orr, Melissa, Wathelet, Marc G.

“…The interferon‐β promoter has been studied extensively as a model system for combinatorial transcriptional regulation. In virus‐infected cells the…”
Get full text

New World hantaviruses activate IFNlambda production in type I IFN-deficient vero E6 cells by Prescott, Joseph, Hall, Pamela, Acuna-Retamar, Mariana, Ye, Chunyan, Wathelet, Marc G, Ebihara, Hideki, Feldmann, Heinz, Hjelle, Brian

“…Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS). These viruses induce a strong…”
Get full text

Transcriptional activity of interferon regulatory factor (IRF)‐3 depends on multiple protein–protein interactions by Yang, Hongmei, Lin, Charles H., Ma, Gang, Orr, Melissa, Baffi, Michael O., Wathelet, Marc G.

“…Virus infection results in the activation of a set of cellular genes involved in host antiviral defense. IRF‐3 has been identified as a critical transcription…”
Get full text

Noxa/HSP27 complex delays degradation of ubiquitylated IkBα in airway epithelial cells to reduce pulmonary inflammation by Zhang, C, Jones, J T, Chand, H S, Wathelet, M G, Evans, C M, Dickey, B, Xiang, J, Mebratu, Y A, Tesfaigzi, Y

“…IFN-γ is known as a pro-inflammatory cytokine, but can also block inflammation in certain chronic diseases although the underlying mechanisms are poorly…”
Get full text

Syndecan-2 Exerts Antifibrotic Effects by Promoting Caveolin-1-mediated Transforming Growth Factor-[Beta] Receptor I Internalization and Inhibiting Transforming Growth Factor-[Beta]1 Signaling by Shi, Yuanyuan, Gochuico, Bernadette R, Yu, Guoying, Tang, Xiaomeng, Osorio, Juan C, Fernandez, Isis E, Risquez, Cristobal F, Patel, Avignat S, Shi, Ying, Wathelet, Marc G, Goodwin, Andrew J, Haspel, Jeffrey A, Ryter, Stefan W, Billings, Eric M, Kaminski, Naftali, Morse, Danielle, Rosas, Ivan O

“…Alveolar transforming growth factor (TGF)-[beta]1 signaling and expression of TGF-[beta]1 target genes are increased in patients with idiopathic pulmonary…”
Get full text

New World Hantaviruses Activate IFN[lambda] Production in Type I IFN-Deficient Vero E6 Cells by Prescott, Joseph, Hall, Pamela, Acuna-Retamar, Mariana, Ye, Chunyan, Wathelet, Marc G, Ebihara, Hideki, Feldmann, Heinz, Hjelle, Brian

“…Background Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS). These viruses induce a strong…”
Get full text

Identification of Residues of SARS-CoV nsp1 That Differentially Affect Inhibition of Gene Expression and Antiviral Signaling. e62416 by Jauregui, Andrew R, Savalia, Dhruti, Lowry, Virginia K, Farrell, Cara M, Wathelet, Marc G

“…An epidemic of Severe Acute Respiratory Syndrome (SARS) led to the identification of an associated coronavirus, SARS-CoV. This virus evades the host innate…”
Get full text

Severe acute respiratory syndrome coronavirus evades antiviral signaling : Role of nspl and rational design of an attenuated strain by WATHELET, Marc G, ORR, Melissa, FRIEMAN, Matthew B, BARIC, Ralph S

Get full text

New World Hantaviruses Activate IFNl Production in Type I IFN-Deficient Vero E6 Cells by Prescott, Joseph, Hall, Pamela, Acuna-Retamar, Mariana, Ye, Chunyan, Wathelet, Marc G, Ebihara, Hideki, Feldmann, Heinz, Hjelle, Brian

“…Hantaviruses indigenous to the New World are the etiologic agents of hantavirus cardiopulmonary syndrome (HCPS). These viruses induce a strong…”
Get full text

Regulation of gene expression by cytokines and virus in human cells lacking the type‐I interferon locus by WATHELET, Marc G., BERR, Pascale M., HUEZ, Georges A.

“…A number of genes that are induced by type‐I interferons are also activated by one or more other inducers, including double‐stranded RNA, viruses,…”
Get full text