Search Results - "WATERFALL, Christy"

16S rRNA Next Generation Sequencing Analysis Shows Bacteria in Alzheimer's Post-Mortem Brain by Emery, David C, Shoemark, Deborah K, Batstone, Tom E, Waterfall, Christy M, Coghill, Jane A, Cerajewska, Tanya L, Davies, Maria, West, Nicola X, Allen, Shelley J

“…The neurological deterioration associated with Alzheimer's disease (AD), involving accumulation of amyloid-beta peptides and neurofibrillary tangles, is…”
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Single tube genotyping of sickle cell anaemia using PCR-based SNP analysis by Waterfall, C M, Cobb, B D

“…Allele-specific amplification (ASA) is a generally applicable technique for the detection of known single nucleotide polymorphisms (SNPs), deletions,…”
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STK15 Polymorphisms and Association with Risk of Invasive Ovarian Cancer by DICIOCCIO, Richard A, HONGLIN SONG, JACOBS, Ian J, PONDER, Bruce A. J, WHITTEMORE, Alice S, GAYTHER, Simon A, PHAROAH, Paul D. P, KRUGER-KJAER, Susan, WATERFALL, Christy, KIMURA, Makoto T, NAGASE, Hiroki, MCGUIRE, Valerie, HOGDALL, Estrid, SHAH, Mitul N, LUBEN, Robert N, EASTON, Douglas F

“…STK15 is a putative oncogene that codes for a centrosome-associated, serine/threonine kinase, the normal function of which is to ensure accurate segregation of…”
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Kinetic characterisation of primer mismatches in allele-specific PCR: a quantitative assessment by Waterfall, Christy M, Eisenthal, Robert, Cobb, Benjamin D

“…A novel method of estimating the kinetic parameters of Taq DNA polymerase during rapid cycle PCR is presented. A model was constructed using a simplified…”
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SNP genotyping using single-tube fluorescent bidirectional PCR by Waterfall, Christy M, Cobb, Benjamin D

“…SNP genotyping is a well-populatedfield with a large number of assay formats offering accurate allelic discrimination. However, there remains a discord between…”
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Characterization of a Wheat Breeders’ Array suitable for high‐throughput SNP genotyping of global accessions of hexaploid bread wheat (Triticum aestivum) by Allen, Alexandra M., Winfield, Mark O., Burridge, Amanda J., Downie, Rowena C., Benbow, Harriet R., Barker, Gary L. A., Wilkinson, Paul A., Coghill, Jane, Waterfall, Christy, Davassi, Alessandro, Scopes, Geoff, Pirani, Ali, Webster, Teresa, Brew, Fiona, Bloor, Claire, Griffiths, Simon, Bentley, Alison R., Alda, Mark, Jack, Peter, Phillips, Andrew L., Edwards, Keith J.

“…Summary Targeted selection and inbreeding have resulted in a lack of genetic diversity in elite hexaploid bread wheat accessions. Reduced diversity can be a…”
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High‐density SNP genotyping array for hexaploid wheat and its secondary and tertiary gene pool by Winfield, Mark O, Allen, Alexandra M, Burridge, Amanda J, Barker, Gary L. A, Benbow, Harriet R, Wilkinson, Paul A, Coghill, Jane, Waterfall, Christy, Davassi, Alessandro, Scopes, Geoff, Pirani, Ali, Webster, Teresa, Brew, Fiona, Bloor, Claire, King, Julie, West, Claire, Griffiths, Simon, King, Ian, Bentley, Alison R, Edwards, Keith J

“…In wheat, a lack of genetic diversity between breeding lines has been recognized as a significant block to future yield increases. Species belonging to bread…”
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CerealsDB: A Whistle-Stop Tour of an Open Access SNP Resource by Winfield, Mark, Wilkinson, Paul, Burridge, Amanda, Allen, Alexandra, Coghill, Jane, Waterfall, Christy, Edwards, Keith, Barker, Gary

“…The CerealsDB website, created by members of the Functional Genomics Group at the University of Bristol, provides access to a database containing SNP and…”
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Inflammatory pathways are central to posterior cerebrovascular artery remodelling prior to the onset of congenital hypertension by Walas, Dawid, Nowicki-Osuch, Karol, Alibhai, Dominic, von Linstow Roloff, Eva, Coghill, Jane, Waterfall, Christy, Paton, Julian FR

“…Cerebral artery hypoperfusion may provide the basis for linking ischemic stroke with hypertension. Brain hypoperfusion may induce hypertension that may serve…”
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High‐density genotyping of the A.E. Watkins Collection of hexaploid landraces identifies a large molecular diversity compared to elite bread wheat by Winfield, Mark O., Allen, Alexandra M., Wilkinson, Paul A., Burridge, Amanda J., Barker, Gary L.A., Coghill, Jane, Waterfall, Christy, Wingen, Luzie U., Griffiths, Simon, Edwards, Keith J.

“…Summary The importance of wheat as a food crop makes it a major target for agricultural improvements. As one of the most widely grown cereal grains, together…”
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CerealsDB 3.0: expansion of resources and data integration by Wilkinson, Paul A, Winfield, Mark O, Barker, Gary L A, Tyrrell, Simon, Bian, Xingdong, Allen, Alexandra M, Burridge, Amanda, Coghill, Jane A, Waterfall, Christy, Caccamo, Mario, Davey, Robert P, Edwards, Keith J

“…The increase in human populations around the world has put pressure on resources, and as a consequence food security has become an important challenge for the…”
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RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways by Jiang, Lulu, Hindmarch, Charles C. T., Rogers, Mark, Campbell, Colin, Waterfall, Christy, Coghill, Jane, Mathieson, Peter W., Welsh, Gavin I.

“…Glucocorticoids are steroids that reduce inflammation and are used as immunosuppressive drugs for many diseases. They are also the mainstay for the treatment…”
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Conversion of array‐based single nucleotide polymorphic markers for use in targeted genotyping by sequencing in hexaploid wheat (Triticum aestivum) by Burridge, Amanda J., Wilkinson, Paul A., Winfield, Mark O., Barker, Gary L. A., Allen, Alexandra M., Coghill, Jane A., Waterfall, Christy, Edwards, Keith J.

“…Summary Wheat breeders and academics alike use single nucleotide polymorphisms (SNPs) as molecular markers to characterize regions of interest within the…”
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High-Density SNP Genotyping Array for Hexaploid Wheat and Its Relatives by Burridge, Amanda J, Winfield, Mark O, Allen, Alexandra M, Wilkinson, Paul A, Barker, Gary L A, Coghill, Jane, Waterfall, Christy, Edwards, Keith J

“…A lack of genetic diversity between wheat breeding lines has been recognized as a significant block to future yield increases. Wheat breeding and prebreeding…”
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Polymorphisms in DNA repair genes and epithelial ovarian cancer risk by Auranen, Annika, Song, Honglin, Waterfall, Christy, DiCioccio, Richard A., Kuschel, Bettina, Kjaer, Susanne K., Hogdall, Estrid, Hogdall, Claus, Stratton, John, Whittemore, Alice S., Easton, Douglas F., Ponder, Bruce A.J., Novik, Karen L., Dunning, Alison M., Gayther, Simon, Pharoah, Paul D.P.

“…DNA repair gene polymorphisms and mutations are known to influence cancer risk. We studied whether polymorphisms in DNA double strand break (DSB) repair genes…”
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Strategies for the detection of single nucleotide polymorphisms using the polymerase chain reaction by Waterfall, Christy Marie

“…PCR is widely used as a research tool for SNP detection because it offers a simple, sensitive and robust platform. Its wider use within clinical diagnostics…”
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