Search Results - "WATARI, Jiro"
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Effect of probiotic Bifidobacterium bifidum G9-1 on the relationship between gut microbiota profile and stress sensitivity in maternally separated rats
Published in Scientific reports (17-08-2018)“…Although gut microbiota and early life events are likely involved in the development of irritable bowel syndrome (IBS), it remains unclear how these factors…”
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Recent understanding of the pathophysiology of functional dyspepsia: role of the duodenum as the pathogenic center
Published in Journal of gastroenterology (01-04-2019)“…Over almost 30 years since functional dyspepsia (FD) was defined, researchers have endeavored to elucidate the pathophysiology of functional gastrointestinal…”
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Magnitude and direction of the association between Clostridium difficile infection and proton pump inhibitors in adults and pediatric patients: a systematic review and meta-analysis
Published in Journal of gastroenterology (01-01-2018)“…Background Clostridium difficile infection (CDI) is a cause of increased morbidity and health care costs among hospitalized patients. Proton pump inhibitors…”
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Helicobacter pylori associated chronic gastritis,clinical syndromes,precancerous lesions,and pathogenesis of gastric cancer development
Published in World journal of gastroenterology : WJG (14-05-2014)“…Helicobacter pylori(H.pylori)infection is well known to be associated with the development of precancerous lesions such as chronic atrophic gastritis(AG),or…”
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Duodenal low‐grade inflammation and expression of tight junction proteins in functional dyspepsia
Published in Neurogastroenterology and motility (01-10-2019)“…Background Duodenal changes in functional dyspepsia (FD) might be related to the development of symptoms. However, relationships among low‐grade inflammation,…”
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Alteration of GLP-1/GPR43 expression and gastrointestinal motility in dysbiotic mice treated with vancomycin
Published in Scientific reports (13-03-2019)“…Gut microbiota plays a pivotal role in various aspects of host physiology, including metabolism, gastrointestinal (GI) motility and hormonal secretion. In the…”
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Childhood abuse history is associated with the development of dyspepsia: a population-based survey in Japan
Published in Journal of gastroenterology (01-07-2015)“…Background Functional dyspepsia (FD) is a heterogeneous disorder, and it is not clear whether childhood abuse influences the severity of dyspeptic symptoms and…”
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Correction to: Magnitude and direction of the association between Clostridium difficile infection and proton pump inhibitors in adults and pediatric patients: a systematic review and meta-analysis
Published in Journal of gastroenterology (01-04-2020)“…In the original publication of the article, Table 1 and Figs. 2a, 2b, 3a were published with errors…”
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Adenosine triphosphate induces P2Y2 activation and interleukin‐8 release in human esophageal epithelial cells
Published in Journal of gastroenterology and hepatology (01-07-2017)“…Background and Aim Immune‐mediated mucosal inflammation characterized by the release of interleukin (IL)‐8 is associated with gastroesophageal reflux disease…”
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Analysis of risk factors for colonic diverticular bleeding and recurrence
Published in Medicine (Baltimore) (01-09-2017)“…The increase in incidence of colonic diverticular bleeding is relative to an age-related rise in the incidence of colonic diverticulosis and use of…”
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Down-regulation of claudin-18 is associated with the proliferative and invasive potential of gastric cancer at the invasive front
Published in PloS one (20-09-2013)“…Claudins are known as tight junction proteins, and their expression pattern in gastric cancer is still controversial. The relationship between the expression…”
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Interferon γ-Induced Nuclear Interleukin-33 Potentiates the Release of Esophageal Epithelial Derived Cytokines
Published in PloS one (17-03-2016)“…Esophageal epithelial cells are an initiating cell type in esophageal inflammation, playing an essential role in the pathogenesis of gastroesophageal reflux…”
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Involvement of gut microbiota in association between GLP-1/GLP-1 receptor expression and gastrointestinal motility
Published in American journal of physiology: Gastrointestinal and liver physiology (01-04-2017)“…The microbiota in the gut is known to play a pivotal role in host physiology by interacting with the immune and neuroendocrine systems in gastrointestinal (GI)…”
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A novel prostanoid EP1 receptor antagonist, ONO-8539, reduces acid-induced heartburn symptoms in healthy male volunteers: a randomized clinical trial
Published in Journal of gastroenterology (01-10-2017)“…Background Patients with proton pump inhibitor (PPI)-refractory gastroesophageal reflux disease (GERD) have unmet clinical needs. Recently, we reported that…”
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Long-term effects of H. pylori eradication on epigenetic alterations related to gastric carcinogenesis
Published in Scientific reports (25-09-2018)“…The risk of gastric cancer (GC) remains in precancerous conditions, including atrophic mucosa and intestinal mucosa (IM), even after H . pylori treatment. To…”
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PAR-2 activation enhances weak acid-induced ATP release through TRPV1 and ASIC sensitization in human esophageal epithelial cells
Published in American journal of physiology: Gastrointestinal and liver physiology (15-10-2015)“…Esophageal visceral hypersensitivity has been proposed to be the pathogenesis of heartburn sensation in nonerosive reflux disease. Protease-activated…”
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Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins
Published in American journal of physiology: Gastrointestinal and liver physiology (15-07-2012)“…Reflux of acid and bile acids contributes to epithelial tissue injury in gastro-esophageal reflux disease. However, the influence of refluxed material on human…”
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Epithelial-derived nuclear IL-33 aggravates inflammation in the pathogenesis of reflux esophagitis
Published in Journal of gastroenterology (01-04-2015)“…Background IL-33 is a new tissue-derived cytokine constitutively expressed in epithelial cells and plays a role in sensing damage caused by inflammatory…”
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A double-blind placebo controlled study of acotiamide hydrochloride for efficacy on gastrointestinal motility of patients with functional dyspepsia
Published in Journal of gastroenterology (01-05-2017)“…Background Acotiamide is widely used to improve symptoms in patients with functional dyspepsia (FD) in multiple large-scale clinical studies, but there are few…”
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