Search Results - "WASSLER, Michael"
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MicroRNA-133a regulates insulin-like growth factor-1 receptor expression and vascular smooth muscle cell proliferation in murine atherosclerosis
Published in Atherosclerosis (01-01-2014)“…Abstract Objective MicroRNA-133a (miR-133a) and insulin-like growth factor-1 (IGF-1) are two different molecules known to regulate cardiovascular cell…”
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2
Rotating microgravity-bioreactor cultivation enhances the hepatic differentiation of mouse embryonic stem cells on biodegradable polymer scaffolds
Published in Tissue engineering. Part A (01-11-2012)“…Embryonic stem (ES) cells are pluripotent cells that are capable of differentiating all the somatic cell lineages, including those in the liver tissue. We…”
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3
Inhibition of Gata4 and Tbx5 by Nicotine-Mediated DNA Methylation in Myocardial Differentiation
Published in Stem cell reports (14-02-2017)“…Maternal nicotine exposure causes alteration of gene expression and cardiovascular programming. The discovery of nicotine-medicated regulation in cardiogenesis…”
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Characterization of a Novel Ubiquitin-Conjugating Enzyme That Regulates β 1,4-Galactosyltransferase-1 in Embryonic Stem Cells
Published in Stem cells (Dayton, Ohio) (01-08-2008)“…In this study we identified a novel galactosyltransferase 1-associating protein (GTAP) by cDNA cloning from a murine embryonic cDNA library using the…”
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5
Identification and Characterization of Cystatin-Related Epididymal Spermatogenic Protein in Human Spermatozoa: Localization in the Equatorial Segment
Published in Biology of reproduction (01-09-2002)“…Our earlier studies in mouse have shown that the cystatin-related epididymal spermatogenic (CRES) protein is highly expressed in elongating spermatids in the…”
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6
Galactosyltransferase function during mammalian fertilization
Published in Cells, tissues, organs (01-01-2001)“…Gamete recognition has been studied extensively in the mouse. In this system, it is generally believed that sperm bind to a class of O-linked oligosaccharides…”
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Subcellular localization of β1,4-galactosyltransferase on bull sperm and its function during sperm-egg interactions
Published in Molecular reproduction and development (01-02-2001)“…The process of sperm–oocyte recognition is a complex interaction between the plasma membrane of sperm and the extracellular matrix of the oocyte. The best…”
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8
Clusterin induces CXCR4 expression and migration of cardiac progenitor cells
Published in Experimental cell research (10-12-2010)“…Clusterin (CST) is a stress-responding protein with multiple biological functions, including the inhibition of apoptosis and inflammation and transport of…”
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MIR–133A REGULATES EXPRESSION OF INSULIN–LIKE GROWTH FACTOR–1 RECEPTOR AND SMOOTH MUSCLE CELL GROWTH PARTLY BY TARGETING GALACTOSYLTRANSFERASE 1–ASSOCIATING PROTEIN
Published in Journal of the American College of Cardiology (12-03-2013)“…IGF-1R protein degradation was inhibited when GTAP was reduced by siRNA-GTAP. [...]miR-133a precursor decreased GTAP while increasing IGF-1R and IGF-1-driven…”
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Inhibition of Neointima Hyperplasia, Inflammation, and Reactive Oxygen Species in Balloon-Injured Arteries by HVJ Envelope Vector-Mediated Delivery of Superoxide Dismutase Gene
Published in Translational stroke research (01-08-2019)“…Extracellular superoxide dismutase (EC-SOD) has been implicated in regulation of vascular function but its underlying molecular mechanism is largely unknown…”
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11
Abstract 527: A Novel Stem Cell Delivery Model for Evaluation of Delivery Using Targeted Bifunctional Liposomes with Ultrasound Enhancement
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2013)“…Abstract only…”
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12
Abstract 17406: Inhibition of MicroRNA-133a Expression is Associated with Poor Growth Response of Vascular Smooth Muscle Cells to Insulin-Like Growth Factor-1 in Apolipoprotein-E Deficient Mice
Published in Circulation (New York, N.Y.) (22-11-2011)“…Abstract only Background and Objective. Alternations in growth and differentiation of vascular smooth muscle cells (SMC) contribute to the pathogenesis of…”
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13
Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells
Published in International journal of cardiology (10-09-2013)“…Abstract Background The stromal compartment of adult adipose tissue consists of mesenchymal stem cells (MSCs) characterized by co-expression of myocardin-A…”
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14
Delivery of Stem Cells to Porcine Arterial Wall with Echogenic Liposomes Conjugated to Antibodies against CD34 and Intercellular Adhesion Molecule-1
Published in Molecular pharmaceutics (01-02-2010)“…In atherosclerosis, the loss of vascular stem cells via apoptosis impairs the capacity of the vascular wall to repair or regenerate the tissue damaged by…”
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15
Liposomal modular complexes for simultaneous targeted delivery of bioactive gases and therapeutics
Published in Journal of controlled release (19-03-2010)“…Intrinsically echogenic liposomes (ELIP) can be adapted to encapsulate nitric oxide to facilitate ultrasound-enhanced delivery of therapeutic agents to…”
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16
Apolipoprotein-J prevention of fetal cardiac myoblast apoptosis induced by ethanol
Published in Biochemical and biophysical research communications (25-05-2007)“…Over-consumption of ethanol (EtOH) represents a major health problem. This study was to test the cytotoxicity of EtOH in cardiac stem cells or myoblasts, and…”
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17
Characterization of a Novel Ubiquitin‐Conjugating Enzyme That Regulates β1,4‐Galactosyltransferase‐1 in Embryonic Stem Cells
Published in Stem cells (Dayton, Ohio) (01-08-2008)“…In this study we identified a novel galactosyltransferase 1‐associating protein (GTAP) by cDNA cloning from a murine embryonic cDNA library using the…”
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18
Clustering of cell surface β1,4-galactosyltransferase I induces transient tyrosine phosphorylation of focal adhesion kinase and loss of stress fibers
Published in Journal of cell science (15-01-2000)“…It is well appreciated that clustering of receptors for the extracellular matrix, most notably the integrins, elicits intracellular signal cascades. One of the…”
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Functional interaction between the SSeCKS scaffolding protein and the cytoplasmic domain of β1,4-galactosyltransferase
Published in Journal of cell science (15-06-2001)“…The β1,4-galactosyltransferase family contains at least seven unique gene products, of which β1,4-galactosyltransferase I (GalT) is the most exhaustively…”
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Apolipoprotein-J Prevention of Cardiac Myobalst Apoptosis Induced by Ethanol
Published in Biochemical and biophysical research communications (28-03-2007)“…Over-consumption of ethanol (EtOH) represents a major health problem. This study was to test the cytotoxicity of EtOH in cardiac stem cells or myoblasts, and…”
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