Search Results - "WASSINK, H"

Association Between Brain-Derived Neurotrophic Factor Val66Met Gene Polymorphism and Progressive Brain Volume Changes in Schizophrenia by Ho, Beng-Choon, Andreasen, Nancy C., Dawson, Jeffrey D., Wassink, Thomas H.

“…Objective: Factors underlying progressive brain volume changes in schizophrenia remain poorly understood. The authors investigated whether a gene polymorphism…”
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Prefrontal Inefficiency Is Associated With Polygenic Risk for Schizophrenia by WALTON, Esther, GEISLER, Daniel, GOLLUB, Randy L, CALHOUN, Vince D, EHRLICH, Stefan, LEE, Phil H, HASS, Johanna, TURNER, Jessica A, JINGYU LIU, SPONHEIM, Scott R, WHITE, Tonya, WASSINK, Thomas H, ROESSNER, Veit

“…Considering the diverse clinical presentation and likely polygenic etiology of schizophrenia, this investigation examined the effect of polygenic risk on a…”
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Examination of AVPR1a as an autism susceptibility gene by WASSINK, T. H, PIVEN, J, VIELAND, V. J, PIETILA, J, GOEDKEN, R. J, FOLSTEIN, S. E, SHEFFIELD, V. C

“…Impaired reciprocal social interaction is one of the core features of autism. While its determinants are complex, one biomolecular pathway that clearly…”
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Pax6 3′ deletion results in aniridia, autism and mental retardation by Davis, L. K., Meyer, K. J., Rudd, D. S., Librant, A. L., Epping, E. A., Sheffield, V. C., Wassink, T. H.

“…The PAX6 gene is a transcription factor expressed early in development, predominantly in the eye, brain and gut. It is well known that mutations in PAX6 may…”
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Inflammatory bowel disease, cancer and medication: Cancer risk in the Dutch population‐based IBDSL cohort by van den Heuvel, Tim R.A., Wintjens, Dion S.J., Jeuring, Steven F.G., Wassink, Maartje H.H., Romberg‐Camps, Marielle J.L., Oostenbrug, Liekele E., Sanduleanu, Silvia, Hameeteman, Wim H., Zeegers, Maurice P., Masclee, Ad A., Jonkers, Daisy M., Pierik, Marie J.

“…The management of inflammatory bowel disease (IBD) has changed since the mid‐1990s (e.g., use of thiopurines/anti‐TNFα agents, improved surveillance programs),…”
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MAPK14 and CNR1 gene variant interactions: effects on brain volume deficits in schizophrenia patients with marijuana misuse by Onwuameze, O E, Nam, K W, Epping, E A, Wassink, T H, Ziebell, S, Andreasen, N C, Ho, B-C

“…Adolescent marijuana use is associated with increased risk for schizophrenia. We previously reported that marijuana misuse in conjunction with specific…”
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MTHFR 677C [rightward arrow] T genotype disrupts prefrontal function in schizophrenia through an interaction with COMT 158Val [rightward arrow] Met by Roffman, Joshua L, Gollub, Randy L, Calhoun, Vince D, Wassink, Thomas H, Weiss, Anthony P, Ho, Beng C, White, Tonya, Clark, Vincent P, Fries, Jill, Andreasen, Nancy C, Goff, Donald C, Manoach, Dara S

“…Understanding how risk genes cumulatively impair brain function in schizophrenia could provide critical insights into its pathophysiology. Working memory…”
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Copy number variations and primary open-angle glaucoma by Davis, Lea K, Meyer, Kacie J, Schindler, Emily I, Beck, John S, Rudd, Danielle S, Grundstad, A Jason, Scheetz, Todd E, Braun, Terry A, Fingert, John H, Alward, Wallace L M, Kwon, Young H, Folk, James C, Russell, Stephen R, Wassink, Thomas H, Sheffield, Val C, Stone, Edwin M

“…This study sought to investigate the role of rare copy number variation (CNV) in age-related disorders of blindness, with a focus on primary open-angle…”
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Linkage Disequilibrium at the Angelman Syndrome Gene UBE3A in Autism Families by Nurmi, Erika L., Bradford, Yuki, Chen, Yi-hui, Hall, Jenifer, Arnone, Brenda, Gardiner, Mary Beth, Hutcheson, Holli B., Gilbert, John R., Pericak-Vance, Margaret A., Copeland-Yates, Susan A., Michaelis, Ron C., Wassink, Thomas H., Santangelo, Susan L., Sheffield, Val C., Piven, Joseph, Folstein, Susan E., Haines, Jonathan L., Sutcliffe, James S.

“…Autistic disorder is a neurodevelopmental disorder with a complex genetic etiology. Observations of maternal duplications affecting chromosome 15q11–q13 in…”
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G72 influences longitudinal change in frontal lobe volume in schizophrenia by Hartz, Sarah M., Ho, Beng-Choon, Andreasen, Nancy C., Librant, Amy, Rudd, Danielle, Epping, Eric A., Wassink, Thomas H.

“…Schizophrenia is a neurodevelopmental psychiatric disorder characterized by a variety of structural brain abnormalities that appear to progress across the…”
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Cerebellar morphology as a predictor of symptom and psychosocial outcome in schizophrenia by Wassink, Thomas H, Andreasen, Nancy C, Nopoulos, Peg, Flaum, Michael

“…Background: In this study, we examined whether brain morphology assessed early in the course of schizophrenia predicted psychosocial or symptomatic outcome…”
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Cannabinoid receptor 1 gene polymorphisms and marijuana misuse interactions on white matter and cognitive deficits in schizophrenia by Ho, Beng-Choon, Wassink, Thomas H, Ziebell, Steven, Andreasen, Nancy C

“…Abstract Marijuana exposure during the critical period of adolescent brain maturation may disrupt neuro-modulatory influences of endocannabinoids and increase…”
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Autism genome-wide copy number variation reveals ubiquitin and neuronal genes by Minshew, Nancy J, Thomas, Kelly, Nurnberger, John I, Crawford, Emily L, Otieno, Frederick, Dawson, Geraldine, Posey, David J, Annaiah, Kiran, Glaberson, Wendy, Wood, Shawn, Meyer, Kacie J, Sleiman, Patrick M. A, Miller, Judith, Munson, Jeffrey, Kim, Cecilia E, Bradfield, Jonathan P, Soorya, Latha, Frackelton, Edward C, Bucan, Maja, Sakurai, Takeshi, Hou, Cuiping, Anagnostou, Evdokia, Piven, Joseph, Schultz, Robert T, Zhang, Haitao, Cook, Edwin H, Schellenberg, Gerard D, Wang, Kai, Flory, James, Rudd, Danielle S, Sweeney, John A, Zurawiecki, Danielle, Grant, Struan F. A, Michaels, Shana, Levy, Susan E, Chiavacci, Rosetta, McMahon, William M, Brune, Camille W, Korvatska, Olena, Klei, Lambertus, Cai, Guiqing, McDougle, Christopher J, Hakonarson, Hakon, Kolevzon, Alexander, Garris, Maria, Silverman, Jeremy M, Wassink, Thomas H, Owley, Thomas, Glessner, Joseph T, Sutcliffe, James S, Reichert, Jennifer, Davis, Lea K, Bernier, Raphael, Game, Rachel M, Devlin, Bernie, Coon, Hilary, Imielinski, Marcin, Estes, Annette, Buxbaum, Joseph D

“…Autism spectrum disorders (ASDs) are childhood neurodevelopmental disorders with complex genetic origins. Previous studies focusing on candidate genes or…”
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Evaluation of FOXP2 as an autism susceptibility gene by Wassink, Thomas H., Piven, Joseph, Vieland, Veronica J., Pietila, Jennifer, Goedken, Rhinda J., Folstein, Susan E., Sheffield, Val C.

“…A mutation in the gene FOXP2 was recently identified as being responsible for a complicated speech and language phenotype in a single large extended pedigree…”
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Germline mosaic transmission of a novel duplication of PXDN and MYT1L to two male half-siblings with autism by Meyer, Kacie J, Axelsen, Michael S, Sheffield, Val C, Patil, Shivanand R, Wassink, Thomas H

“…Autism is a neurodevelopmental disorder with a strong genetic component to susceptibility. In this study, we report the molecular characterization of an…”
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Reelin gene alleles and haplotypes as a factor predisposing to autistic disorder by PERSICO, A. M, D'AGRUMA, L, MONTECCHI, F, PALERMO, M, PASCUCCI, T, PUGLISI-ALLEGRA, S, REICHELT, K.-L, CONCIATORI, M, MARINO, R, QUATTROCCHI, C. C, BALDI, A, ZELANTE, L, MAIORANO, N, GASPARINI, P, KELLER, F, TOTARO, A, MILITERNI, R, BRAVACCIO, C, WASSINK, T. H, SCHNEIDER, C, MELMED, R, TRILLO, S

“…Autistic disorder (MIM 209850) is currently viewed as a neurodevelopmental disease. Reelin plays a pivotal role in the development of laminar structures…”
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Common genetic variants on 5p14.1 associate with autism spectrum disorders by Hakonarson, Hakon, Wang, Kai, Zhang, Haitao, Ma, Deqiong, Bucan, Maja, Glessner, Joseph T, Abrahams, Brett S, Salyakina, Daria, Imielinski, Marcin, Bradfield, Jonathan P, Sleiman, Patrick M. A, Kim, Cecilia E, Hou, Cuiping, Frackelton, Edward, Chiavacci, Rosetta, Takahashi, Nagahide, Sakurai, Takeshi, Rappaport, Eric, Lajonchere, Clara M, Munson, Jeffrey, Estes, Annette, Korvatska, Olena, Piven, Joseph, Sonnenblick, Lisa I, Alvarez Retuerto, Ana I, Herman, Edward I, Dong, Hongmei, Hutman, Ted, Sigman, Marian, Ozonoff, Sally, Klin, Ami, Owley, Thomas, Sweeney, John A, Brune, Camille W, Cantor, Rita M, Bernier, Raphael, Gilbert, John R, Cuccaro, Michael L, McMahon, William M, Miller, Judith, State, Matthew W, Wassink, Thomas H, Coon, Hilary, Levy, Susan E, Schultz, Robert T, Nurnberger, John I, Haines, Jonathan L, Sutcliffe, James S, Cook, Edwin H, Minshew, Nancy J, Buxbaum, Joseph D, Dawson, Geraldine, Grant, Struan F. A, Geschwind, Daniel H, Pericak-Vance, Margaret A, Schellenberg, Gerard D

“…Autism spectrum disorders (ASDs) represent a group of childhood neurodevelopmental and neuropsychiatric disorders characterized by deficits in verbal…”
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Prevalence of Depressive Symptoms Early in the Course of Schizophrenia by Wassink, Thomas H., Flaum, Michael, Nopoulos, Peg, Andreasen, Nancy C.

“…OBJECTIVE: The rate of depressive symptoms early in the course of schizophrenia was determined. METHOD: Seventy subjects with recent-onset schizophrenia were…”
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Chromosomal abnormalities in a clinic sample of individuals with autistic disorder by Wassink, T H, Piven, J, Patil, S R

“…We examined data from the largest reported sample of autistic individuals who have been karyotyped with the aim of providing additional information in the…”
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Copy number variations on chromosome 12q14 in patients with normal tension glaucoma by FINGERT, John H, ROBIN, Alan L, MULLINS, Robert F, SHEFFIELD, Val C, STONE, Edwin M, STONE, Jennifer L, ROOS, Ben R, DAVIS, Lea K, SCHEETZ, Todd E, BENNETT, Steve R, WASSINK, Thomas H, KWON, Young H, ALWARD, Wallace L. M

“…We report identification of a novel genetic locus (GLC1P) for normal tension glaucoma (NTG) on chromosome 12q14 using linkage studies of an African-American…”
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