Search Results - "WASOWSKA, Barbara A"

The interaction between ischemia–reperfusion and immune responses in the kidney by Jang, Hye Ryoun, Ko, Gang Jee, Wasowska, Barbara A., Rabb, Hamid

“…Kidney ischemia–reperfusion injury (IRI) engages both the innate and adaptive immune responses. Cellular mediators of immunity, such as dendritic cells,…”
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Antibody to human leukocyte antigen triggers endothelial exocytosis by Yamakuchi, Munekazu, Kirkiles-Smith, Nancy C, Ferlito, Marcella, Cameron, Scott J, Bao, Clare, Fox-Talbot, Karen, Wasowska, Barbara A, Baldwin, William M. III, Pober, Jordan S, Lowenstein, Charles J

“…Although antibodies to HLA play a role in the pathogenesis of diseases processes such as rejection of transplanted organs, the precise mechanisms by which…”
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Non‐Complement‐ and Complement‐Activating Antibodies Synergize to Cause Rejection of Cardiac Allografts by Rahimi, Salma, Qian, Zhiping, Layton, Jodi, Fox‐Talbot, Karen, Baldwin, William M., Wasowska, Barbara A.

“…Alloantibodies (AlloAbs) are a clinically significant component of the immune response to organ transplants. In our experimental model, B10.A (H‐2a) cardiac…”
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Mechanisms involved in antibody- and complement-mediated allograft rejection by Wasowska, Barbara A.

“…Antibody-mediated rejection has become critical clinically because this form of rejection is usually unresponsive to conventional anti-rejection therapy, and…”
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Membrane Attack Complex Contributes to Destruction of Vascular Integrity in Acute Lung Allograft Rejection by Nakashima, Shinji, Qian, Zhiping, Rahimi, Salma, Wasowska, Barbara A, Baldwin, William M., III

“…The lung is known to be particularly susceptible to complement-mediated injury. Both C5a and the membrane attack complex (MAC), which is formed by the terminal…”
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Absence of FcγRIII Results in Increased Proinflammatory Response in FcγRIII-KO Cardiac Recipients by Erdinc Sunay, Melek M, Fox-Talbot, Karen, Velidedeoglu, Ergun, Baldwin, William M, Wasowska, Barbara A

“…BACKGROUNDAlloantibody can contribute significantly to rejection of heart transplants by activation of complement and interactions with a variety of effector…”
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C6 Produced by Macrophages Contributes to Cardiac Allograft Rejection by Qian, Zhiping, Wasowska, Barbara A., Behrens, Edward, Cangello, David L., Brody, Jonathan R., Kadkol, ShriHari S., Horwitz, Louis, Liu, Jinhuan, Lowenstein, Charles, Hess, Allan D., Sanfilippo, Fred, Baldwin, William M.

“…The terminal components of complement C5b-C9 can cause significant injury to cardiac allografts. Using C6-deficient rats, we have found that the rejection of…”
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Cross-talk between innate and adaptive immune responses in infection, transplant and autoimmune models by Wasowska, Barbara A

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Kidney-Derived Mesenchymal Stromal Cells Modulate Dendritic Cell Function to Suppress Alloimmune Responses and Delay Allograft Rejection by YANFEI HUANG, PING CHEN, ZHANG, Cassie B, GANG JEE KO, RUIZ, Miriam, FIORINA, Paolo, HUSSAIN, Mehboob A, WASOWSKA, Barbara A, RABB, Hamid, WOMEN, Karl L

“…Mesenchymal stromal cells (MSCs) are multipotent cells with immunoregulatory capacity that are present in most adult organs. We previously demonstrated that…”
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The Involvement of FcR Mechanisms in Antibody-Mediated Rejection by LEE, Chih-Yuan, LOTFI-EMRAN, Sahar, ERDINC, Melek, MURATA, Kazunori, VELIDEDEOGLU, Ergun, FOX-TALBOT, Karen, JINHUAN LIU, GARYU, Justin, BALDWIN, William M, WASOWSKA, Barbara A

“…Antibody-mediated rejection is characterized by macrophage margination against vascular endothelium. The potential interactions triggered by antibodies between…”
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New concepts of complement in allorecognition and graft rejection by Wasowska, Barbara A., Lee, Chih-Yuan, Halushka, Marc K., Baldwin, William M.

“…In transplantation, activation of complement has largely been equated to antibody-mediated rejection, but complement is also important in recognition of…”
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Beyond C4d: Other Complement‐Related Diagnostic Approaches to Antibody‐Mediated Rejection by Baldwin, William M., Kasper, Edward K., Zachary, Andrea A., Wasowska, Barbara A., Rodriguez, E. Rene

“…Complement is a multifunctional system of receptors and regulators as well as effector molecules. Both the pathogenic and diagnostic power of complement is…”
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Passive transfer of alloantibodies restores acute cardiac rejection in IgKO MICE by WASOWSKA, Barbara A, ZHIPING QIAN, CANGELLO, David L, BEHRENS, Edward, VAN TRAN, Khanh, LAYTON, Jodi, SANFILIPPO, Fred, BALDWIN, William M

“…Alloantibody is an intrinsic component of the immune response to organ transplants. Although alloantibodies have been correlated with decreased graft survival,…”
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Wojciech A. Rowicski, M.D., Ph.D. (1935Y2014): humanist, transplant surgeon and scientist by Kupiec-Weglinski, Jerzy W, Stepkowski, Stanislaw, Wasowska, Barbara A, Hardy, Mark A

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Antibody and complement mediated injury in transplants following sensitization by allogeneic blood transfusion by ZHIPING QIAN, LEE, Chih-Yuan, MURATA, Kazunori, JINHUAN LIU, FOX-TALBOT, Karen, WASOWSKA, Barbara A, BALDWIN, William M

“…Many patients on the waiting list for transplants are sensitized from previous blood transfusions, pregnancy, or transplants. We investigated the role of…”
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The CD154-CD40 T Cell Costimulation Pathway Is Required for Host Sensitization of CD8+ T Cells by Skin Grafts Via Direct Antigen Presentation by Zhai, Yuan, Shen, Xiu-Da, Gao, Feng, Coito, Ana J, Wasowska, Barbara A, Salama, Alan, Schmitt, Isabela, Busuttil, Ronald W, Sayegh, Mohamed H, Kupiec-Weglinski, Jerzy W

“…Although the CD154-CD40 T cell costimulation pathway has been shown to mediate alloimmune responses in normal recipients, little is known about its role in…”
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Inducible nitric oxide synthase inhibition of Weibel-Palade body release in cardiac transplant rejection by ZHIPING QIAN, GELZER-BELL, Ramona, YANG, Shui-Xiang, WANGSEN CAO, OHNISHI, Tomokazu, WASOWSKA, Barbara A, HRUBAN, Ralph H, RODRIGUEZ, E. Rene, BALDWIN, William M, LOWENSTEIN, Charles J

“…Inducible nitric oxide synthase (iNOS, or NOS2) reduces the severity of accelerated graft arteriosclerosis (AGA) in transplanted organs, although the precise…”
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Impact of MHC Class II Incompatibility on Localization of Mononuclear Cell Infiltrates to the Bronchiolar Compartment of Orthotopic Lung Allografts by Nakashima, Shinji, Soong, T. Rinda, Fox‐Talbot, Karen, Qian, Zhiping, Rahimi, Salma, Wasowska, Barbara A., Rohde, Charles A., Chen, Sabrina, Garcia, Joe G.N., Baldwin, William M.

“…Chronic pathological changes in transplanted lungs are unique because they center on the airways. We examined the relative role of MHC class I and II antigens…”
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Wojciech A. Rowiński, M.D., Ph.D. (1935–2014): Humanist, Transplant Surgeon and Scientist by Kupiec-Weglinski, Jerzy W., Stepkowski, Stanislaw, Wasowska, Barbara A., Hardy, Mark A

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The absence of FcγRIII results in increased pro-inflammatory response in FcγRIII-KO cardiac recipients by Erdinc Sunay, Melek M., Fox-Talbot, Karen, Velidedeoglu, Ergun, Baldwin, William M., Wasowska, Barbara A.

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