Search Results - "WASHINGTON, C. B"

The Disposition of Saquinavir in Normal and P-glycoprotein Deficient Mice, Rats, and in Cultured Cells by WASHINGTON, C. B, WILTSHIRE, H. R, BLASCHKE, T. F, MAN, M, MOY, T, HARRIS, S. R, WORTH, E, WEIGL, P, LIANG, Z, HALL, D, MARRIOTT, L

“…Protease inhibitors are very effective in treating patients infected with HIV. However, many drugs in this class penetrate poorly into the central nervous…”
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Interactions of HIV Protease Inhibitors with a Human Organic Cation Transporter in a Mammalian Expression System by Zhang, L, Gorset, W, Washington, C B, Blaschke, T F, Kroetz, D L, Giacomini, K M

“…Recently, we cloned a human organic cation transporter, hOCT1, which is expressed primarily in the liver. hOCT1 plays an important role in the cellular uptake…”
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Electric Charge Gaussian Gradation Method (ECGGM): A technique for improving material interface representations for the radial point interpolation method by Oliveira, Rodrigo M. S., Brandão, Marcelo B. S., Sousa, Washington C. B.

“…An improved meshless discretization methodology, based on the Coulomb's law discretization method, is introduced. With the presented improvement, it is…”
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Chemical, enzymatic, and human enantioselective S-oxygenation of cimetidine by Cashman, J R, Park, S B, Yang, Z C, Washington, C B, Gomez, D Y, Giacomini, K M, Brett, C M

“…The S-oxygenation of cimetidine was investigated using achiral chemical and chiral chemical and enzymatic S-oxygenation procedures. The products of the…”
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Interaction of nucleoside analogues with the sodium-nucleoside transport system in brush border membrane vesicles from human kidney by BRETT, C. M, WASHINGTON, C. B, OTT, R. J, GUTIERREZ, M. M, GIACOMINI, K. M

“…The therapeutic efficacy of nucleosides and nucleoside analogues as antitumor, antiviral, antiparasitic, and antiarrhythmic agents has been well documented…”
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Hemostasis changes during cardiopulmonary bypass surgery by Mammen, E F, Koets, M H, Washington, B C, Wolk, L W, Brown, J M, Burdick, M, Selik, N R, Wilson, R F

“…A number of hemostasis parameters were studied in a total of 63 patients undergoing cardiopulmonary bypass (CPB) for open heart surgery. In 33 patients…”
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The effect of N-ethylmaleimide on the Na(+)-dependent nucleoside transporter (N3) in rabbit choroid plexus by Washington, C B, Brett, C M, Wu, X, Giacomini, K M

“…The effect of the irreversible sulfhydryl-modifying agent, N-ethylmaleimide (NEM), on the transport of purine and pyrimidine nucleosides in choroid plexus was…”
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Nucleoside transport in isolated human and rhesus choroid plexus tissue slices by WASHINGTON, C. B, GIACOMINI, K. M, BRETT, C. M

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Mechanisms of 5-fluorouracil (5-FU) transport in isolated rabbit choroid plexus tissue slices by WASHINGTON, C. B, GIACOMINI, K. M

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Na(+)-dependent purine nucleoside transporter from human kidney: cloning and functional characterization by Wang, J, Su, S F, Dresser, M J, Schaner, M E, Washington, C B, Giacomini, K M

“…Many purine nucleosides and their analogs are actively transported in the kidney. Using homology cloning strategies and reverse transcriptase-polymerase chain…”
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Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells by WASHINGTON, C. B, DURAN, G. E, MAN, M. C, SIKIC, B. I, BLASCHKE, T. F

“…The anti-HIV protease inhibitors represent a new class of agents for treatment of HIV infection. Saquinavir, ritonavir, indinavir, and nelfinavir are the first…”
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Mechanisms of nucleobase transport in rabbit choroid plexus. Evidence for a Na(+)-dependent nucleobase transporter with broad substrate selectivity by Washington, C B, Giacomini, K M

“…The overall goal of this study was to determine the mechanisms by which nucleobases are transported in the choroid plexus. Choroid plexus tissue slices were…”
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A Meshless Discretization Methodology Based on Lennard-Jones Forces by de Oliveira, Rodrigo M. S., Sousa, Washington C. B., Rabelo, Wilson R. M.

“…A meshless discretization methodology based on the Lennard-Jones force is presented. The new methodology, named Lennard-Jones discretization method (LJDM), can…”
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Cefamandole-erythromycin-heparin peritoneal irrigation: an adjunct to the surgical treatment of diffuse bacterial peritonitis by Washington, B C, Villalba, M R, Lauter, C B, Colville, J, Starnes, R

“…The enthusiasm for the use of peritoneal irrigation has waxed and waned since its introduction by Dr. Pierce in 1905. The purpose of this study was to devise a…”
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Methods of study drug transport in isolated choroid plexus tissue and cultured cells by Washington, C B, Giacomini, K M, Brett, C M

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Population pharmacokinetics of trastuzumab in patients With HER2+ metastatic breast cancer by BRUNO, Rene, WASHINGTON, Carla B, LU, Jian-Feng, LIEBERMAN, Grazyna, BANKEN, Ludger, KLEIN, Pamela

“…To characterize the population pharmacokinetics of trastuzumab in patients with metastatic breast cancer. A nonlinear mixed effect model was based on…”
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Factors That Influence Immediate Perforator Vein Closure Rates With Radiofrequency Ablation, Laser Ablation, or Foam Sclerotherapy by Hager, E, Steinmetz, A, Washington, C.B, Wu, T, Singh, M.J, Kenkre, T.S, Dillavou, E

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Adenosine A1 receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury by Kochanek, Patrick M, Vagni, Vincent A, Janesko, Keri L, Washington, Christopher B, Crumrine, Patricia K, Garman, Robert H, Jenkins, Larry W, Clark, Robert SB, Homanics, Gregg E, Dixon, C Edward, Schnermann, Jurgen, Jackson, Edwin K

“…Adenosine, acting at A1 receptors, exhibits anticonvulsant effects in experimental epilepsy—and inhibits progression to status epilepticus (SE). Seizures after…”
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Intraabdominal venous injuries by Greig, J D, Washington, B C, Wilson, R F, Whelan, Jr, T J

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Mechanisms of nucleobase transport in rabbit choroid plexus: Evidence for a Na super(+)-dependent nucleobase transporter with broad substrate selectivity by Washington, C B, Giacomini, K M

“…The overall goal of this study was to determine the mechanisms by which nucleobases are transported in the choroid plexus. Choroid plexus tissue slices were…”
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