Search Results - "WASCHER, T. C."

The influence of probiotic supplementation on gut permeability in patients with metabolic syndrome: an open label, randomized pilot study by Leber, B, Tripolt, N J, Blattl, D, Eder, M, Wascher, T C, Pieber, T R, Stauber, R, Sourij, H, Oettl, K, Stadlbauer, V

“…Background/objectives: Obesity and metabolic disorders are linked to inflammation via gut microbiota and/or gut permeability. Gut-derived endotoxin triggers…”
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Reduction of postchallenge hyperglycaemia prevents acute endothelial dysfunction in subjects with impaired glucose tolerance by Wascher, T. C., Schmoelzer, I., Wiegratz, A., Stuehlinger, M., Mueller-Wieland, D., Kotzka, J., Enderle, M.

“…Objectives  To investigate whether selective reduction of postchallenge hyperglycaemia influences acute endothelial dysfunction, a very early manifestation of…”
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Non-glycemic effects of insulin therapy: a comparison between insulin aspart and regular human insulin during two consecutive meals in patients with type 2 diabetes by Sourij, H, Schmoelzer, I, de Campo, A, Tripolt, N J, Stojakovic, T, Scharnagl, H, Kettler-Schmut, E, Forst, T, Wascher, T C

“…ObjectiveTo control postprandial hyperglycemia in insulin-treated type 2 diabetic patients, prandial therapy with regular human insulin (HI) or fast acting…”
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Differential effects of fluvastatin alone or in combination with ezetimibe on lipoprotein subfractions in patients at high risk of coronary events by Stojakovic, T., De Campo, A., Scharnagl, H., Sourij, H., Schmölzer, I., Wascher, T. C., März, W.

“…Eur J Clin Invest 2010; 40 (3): 187–194 Background  Ezetimibe, a cholesterol‐absorption inhibitor, significantly lowers low‐density lipoprotein cholesterol…”
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Improvement of insulin sensitivity in insulin resistant subjects during prolonged treatment with the anti-TNF-α antibody infliximab by Yazdani-Biuki, B., Stelzl, H., Brezinschek, H. P., Hermann, J., Mueller, T., Krippl, P., Graninger, W., Wascher, T. C.

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Injection therapy of diabetes by Lechleitner, Monika, Roden, Michael, Weitgasser, Raimund, Ludvik, Bernhard, Fasching, Peter, Hoppichler, Friedrich, Kautzky-Willer, Alexandra, Schernthaner, Guntram, Prager, Rudolf, Kaser, Susanne, Wascher, T C

“…The present article is a recommendation of the Austrian Diabetes Association for the practical use of injection therapy (GLP1-receptor agonists and insulin) in…”
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The alpha-amino group of l-arginine mediates its antioxidant effect by Wallner, S., Hermetter, A., Mayer, B., Wascher, T. C.

“…Antioxidant effects may constitute part of the possible antiatherogenic effects of the amino acid l‐arginine. These antioxidant properties were further…”
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Short communication: Effect of supplementation with Lactobacillus casei Shirota on insulin sensitivity, β-cell function, and markers of endothelial function and inflammation in subjects with metabolic syndrome--a pilot study by Tripolt, N J, Leber, B, Blattl, D, Eder, M, Wonisch, W, Scharnagl, H, Stojakovic, T, Obermayer-Pietsch, B, Wascher, T C, Pieber, T R, Stadlbauer, V, Sourij, H

“…Based on animal studies, intake of probiotic bacteria was suggested to improve insulin sensitivity by reducing endotoxinemia and inflammation. The objective of…”
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Low-fat, high-carbohydrate (low-glycaemic index) diet induces weight loss and preserves lean body mass in obese healthy subjects: results of a 24-week study by Bahadori, B., Yazdani-Biuki, B., Krippl, P., Brath, H., Uitz, E., Wascher, T. C.

“…Background:  The traditional treatment for obesity which is based on a reduced caloric diet has only been partially successful. Contributing factors are not…”
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Intense cholesterol lowering therapy with a HMG-CoA reductase inhibitor does not improve nitric oxide dependent endothelial function in type-2-diabetes--a multicenter, randomised, double-blind, three-arm placebo-controlled clinical trial by Balletshofer, B M, Goebbel, S, Rittig, K, Enderle, M, Schmölzer, I, Wascher, T C, Ferenc Pap, A, Westermeier, T, Petzinna, D, Matthaei, S, Häring, H U

“…Disturbances in nitric oxide (NO) metabolism resulting in endothelial dysfunction play a central role in the pathogenesis of atherosclerosis in…”
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Effects of low-dose l-arginine on insulin-mediated vasodilatation and insulin sensitivity by WASCHER, T. C., GRAIER, W. F., DITTRICH, P., HUSSAIN, M. A., BAHADORI, B., WALLNER, S., TOPLAK, H.

“…The present study was carried out to evaluate the effect of a low‐dose intravenous supplementation of l‐arginine on insulin‐mediated vasodilatation and insulin…”
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Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in endothelial cells by POSCH, K, SIMECEK, S, WASCHER, T. C, JÜRGENS, G, BAUMGARTNER-PARZER, S, KOSTNER, G. M, GRAIER, W. F

“…Glycated low-density lipoprotein attenuates shear stress-induced nitric oxide synthesis by inhibition of shear stress-activated L-arginine uptake in…”
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Alterations in platelet Ca2+ signalling in diabetic patients is due to increased formation of superoxide anions and reduced nitric oxide production by SCHAEFFER, G, WASCHER, T. C, KOSTNER, G. M, GRAIER, W. F

“…Increased aggregation of platelets might contribute to the development of vascular complication in diabetes mellitus. In this study release of superoxide…”
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Multifactorial risk factor intervention in patients with Type2 diabetes improves arginine bioavailability ratios by Tripolt, N J, Meinitzer, A, Eder, M, Wascher, T C, Pieber, T R, Sourij, H

“…Aim Endothelial dysfunction is defined by reduced bioavailability of nitric oxide and has been shown to be associated with cardiovascular risk. The global…”
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Multifactorial risk factor intervention in patients with Type 2 diabetes improves arginine bioavailability ratios by Tripolt, N. J., Meinitzer, A., Eder, M., Wascher, T. C., Pieber, T. R., Sourij, H.

“…Diabet. Med. 29, e365–e368 (2012) Aim  Endothelial dysfunction is defined by reduced bioavailability of nitric oxide and has been shown to be associated with…”
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Biphasic insulin aspart compared to biphasic human insulin reduces postprandial hyperlipidemia in patients with Type 2 diabetes by Schmoelzer, I, de Campo, A, Pressl, H, Stelzl, H, Dittrich, P, Oettl, K, Wascher, T C

“…Premixed insulin analogues reduce postprandial hyperglycemia in patients with Type 2 diabetes in comparison to premixed regular insulin. Insulin also plays an…”
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Contribution of the endothelium to transcapillary insulin transport in rat isolated perfused hearts by BRUNNER, F, WASCHER, T. C

“…Contribution of the endothelium to transcapillary insulin transport in rat isolated perfused hearts. F Brunner and T C Wascher Department of Pharmacology and…”
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Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide synthase with manifest coronary artery disease, carotid atherosclerosis and forearm vascular reactivity in two Austrian populations by Schmoelzer, I., Renner, W., Paulweber, B., Malaimare, L., Iglseder, B., Schmid, P., Schallmoser, K., Wascher, T. C.

“…Objective Conflicting data exists about the possible contribution of the homozygous Asp/Asp genotype of the Glu298Asp polymorphism of endothelial nitric oxide…”
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Increased superoxide anion formation in endothelial cells during hyperglycemia: an adaptive response or initial step of vascular dysfunction? by Graier, Wolfgang F., Posch, Karla, Fleischhacker, Eleonore, Wascher, Thomas C., Kostner, Gert M.

“…In diabetes mellitus, the risk for cardiovascular complications and development of atherosclerosis is increased compared with healthy individuals. Recently…”
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Delayed insulin transport across endothelium in insulin-resistant JCR:LA-cp rats by Wascher, T C, Wölkart, G, Russell, J C, Brunner, F

“…Delayed insulin transport across endothelium in insulin-resistant JCR:LA-cp rats. T C Wascher , G Wölkart , J C Russell and F Brunner Department of Internal…”
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