Search Results - "WASCHEK, J.A."

Atomoxetine reverses locomotor hyperactivity, impaired novel object recognition, and prepulse inhibition impairment in mice lacking pituitary adenylate cyclase-activating polypeptide by Shibasaki, Y, Hayata-Takano, A, Hazama, K, Nakazawa, T, Shintani, N, Kasai, A, Nagayasu, K, Hashimoto, R, Tanida, M, Katayama, T, Matsuzaki, S, Yamada, K, Taniike, M, Onaka, Y, Ago, Y, Waschek, J.A, Köves, K, Reglődi, D, Tamas, A, Matsuda, T, Baba, A, Hashimoto, H

“…Highlights • ATX significantly alleviated ADHD-related behavioral abnormalities of PACAP−/− mice. • ATX significantly alleviated impaired prepulse inhibition…”
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Impaired nerve regeneration and enhanced neuroinflammatory response in mice lacking pituitary adenylyl cyclase activating peptide by Armstrong, B.D, Abad, C, Chhith, S, Cheung-Lau, G, Hajji, O.E, Nobuta, H, Waschek, J.A

“…Abstract Peripheral nerve injury models are used to investigate processes that can potentially be exploited in CNS injury. A consistent change that occurs in…”
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PACAP deficiency sensitizes nigrostriatal dopaminergic neurons to paraquat-induced damage and modulates central and peripheral inflammatory activation in mice by Watson, M.B, Nobuta, H, Abad, C, Lee, S.K, Bala, N, Zhu, C, Richter, F, Chesselet, M.-F, Waschek, J.A

“…Highlights • An interplay between an environmental factor and a gene is demonstrated in a mouse model. • PACAP loss increases sensitivity to a pesticide…”
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Developmental actions of natriuretic peptides in the brain and skeleton by Waschek, J A

“…The concept that atrial natriuretic peptide (ANP) and the closely related peptides BNP and CNP might be involved in the ontogeny of several organ systems…”
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Embryonic expression and multifunctional actions of the natriuretic peptides and receptors in the developing nervous system by DiCicco-Bloom, E., Lelièvre, V., Zhou, X., Rodriguez, W., Tam, J., Waschek, J.A.

“…Atrial natriuretic peptide (ANP) binding sites have been detected in the embryonic brain, but the specific receptor subtypes and biological functions for ANP…”
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Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide: A model for the study of intestinal ileus and Hirschsprung's disease by Lelievre, V., Favrais, G., Abad, C., Adle-Biassette, H., Lu, Y., Germano, P.M., Cheung-Lau, G., Pisegna, J.R., Gressens, P., Lawson, G., Waschek, J.A.

“…In 1970, Drs. Said and Mutt isolated a novel peptide from porcine intestinal extracts with powerful vasoactive properties, and named it vasoactive intestinal…”
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Clues to VIP Function from Knockout Mice by HAMIDI, S.A., SZEMA, A.M., LYUBSKY, S., DICKMAN, K.G., DEGENE, A., MATHEW, S.M., WASCHEK, J.A., SAID, S.I.

“…:  We have taken advantage of the availability of vasoactive intestinal polypeptide (VIP) knockout (KO) mice to examine the possible influence of deletion of…”
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Paradoxical antagonism of PACAP receptor signaling by VIP in Xenopus oocytes via the type-C natriuretic peptide receptor by Lelièvre, V., Hu, Z., Ioffe, Y., Byun, J.-Y., Flores, A., Seksenyan, A., Waschek, J.A.

“…Atrial natriuretic peptide (ANP) and the closely-related peptides BNP and CNP are highly conserved cardiovascular hormones. They bind to single…”
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Induction of neuropeptide gene expression and blockade of retrograde transport in facial motor neurons following local peripheral nerve inflammation in severe combined immunodeficiency and BALB/C mice by Armstrong, B.D., Hu, Z., Abad, C., Yamamoto, M., Rodriguez, W.I., Cheng, J., Lee, M., Chhith, S., Gomariz, R.P., Waschek, J.A.

“…Peripheral nerve inflammation is a common clinical problem that accompanies nerve injury and several diseases including Guillain-Barré syndrome and acute and…”
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Local action of estrogen and thyroid hormone on vasoactive intestinal peptide (VIP) and galanin gene expression in the ratanterior pituitary by Degerman, A., Chun, D., Nguyen, T.B., Bravo, D.T., Alanis, J., Rökaeus, Å., Waschek, J.A.

“…Neuropeptides act within the pituitary as autocrine or paracrine factors, modulating the synthesis and release of primary pituitary hormones, and possibly…”
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Transcription Initiation Is Localized to a TATA-less Region in the Ovine β1 Adrenergic Receptor Gene by Padbury, J.F., Tseng, Y.T., Waschek, J.A.

“…We cloned and sequenced the ovine beta1 adrenergic receptor (β1AR) gene and promoter region. The transcription start site was localized by RNase protection and…”
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The polypeptide PHI discriminates a GTP-insensitive form of vip receptor in livermembranes by Pineau, N., Lelievre, V., Goursaud, S., Hilairet, S., Waschek, J.A., Janet, T., Muller, J-M

“…In early reports on125I-VIP binding experiments in liver membranes, it has been proposed that, the VIP binding sites were partially sensitive to GTP. Here we…”
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Functional Analysis of the 5′ Flanking Sequence in the Ovine β1-Adrenergic Receptor Gene by Tseng, Y.T., Waschek, J.A., Padbury, J.F.

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Functional Analysis of the 5′ Flanking Sequence in the Ovine β 1-Adrenergic Receptor Gene by Tseng, Y.T., Waschek, J.A., Padbury, J.F.

“…Functional data for the promoter of the β 1-adrenergic receptor (β 1AR) gene are lacking. We previously cloned the ovine β 1AR gene and mapped the…”
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A cloning strategy for G-protein-coupled hormone receptors: the ovine beta 1-adrenergic receptor by Padbury, J F, Tseng, Y T, Waschek, J A

“…Regulation of beta 1-adrenergic receptors is unusual in developing animals. For example, glucocorticoid-and thyroid hormone-responsiveness for several genes is…”
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Barium distinguishes separate calcium targets for synthesis and secretion of peptides in neuroendocrine cells by Waschek, J A, Dave, J R, Eskay, R L, Eiden, L E

“…The effect of barium and potassium on the secretion and biosynthesis of enkephalin in bovine chromaffin cells, and prolactin and beta-endorphin in rat anterior…”
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