Search Results - "WARREN, J"

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  1. 1

    Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy by Liao, Wei, Lin, Jian-Xin, Leonard, Warren J.

    Published in Immunity (Cambridge, Mass.) (24-01-2013)
    “…Interleukin-2 (IL-2) is a pleiotropic cytokine produced after antigen activation that plays pivotal roles in the immune response. Discovered as a T cell growth…”
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  2. 2

    Role of thymic stromal lymphopoietin in allergy and beyond by Ebina-Shibuya, Risa, Leonard, Warren J.

    Published in Nature reviews. Immunology (01-01-2023)
    “…Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell lineages, including dendritic cells, T cells, B cells, neutrophils,…”
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  3. 3

    Biology and regulation of IL-2: from molecular mechanisms to human therapy by Spolski, Rosanne, Li, Peng, Leonard, Warren J.

    Published in Nature reviews. Immunology (01-10-2018)
    “…IL-2 was first identified as a growth factor capable of driving the expansion of activated human T cell populations. In the more than 40 years since its…”
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  4. 4

    Interleukin-21: a double-edged sword with therapeutic potential by Spolski, Rosanne, Leonard, Warren J.

    Published in Nature reviews. Drug discovery (01-05-2014)
    “…Key Points Interleukin-21 (IL-21) is a pleiotropic cytokine with actions on a broad range of lymphoid, myeloid and epithelial cells. These actions include…”
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  5. 5

    Controlling the Oxygen Reduction Selectivity of Asymmetric Cobalt Porphyrins by Using Local Electrostatic Interactions by Zhang, Rui, Warren, Jeffrey J

    Published in Journal of the American Chemical Society (05-08-2020)
    “…The development and improvement of electrocatalysts for the 4H+/4e– reduction of O2 to H2O is an ongoing challenge. The addition of ancillary groups (e.g.,…”
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  6. 6

    Biology of IL‐2 and its therapeutic modulation: Mechanisms and strategies by Mitra, Suman, Leonard, Warren J.

    Published in Journal of leukocyte biology (01-04-2018)
    “…Cytokines signal through specific cell surface receptors to broadly regulate immune development, differentiation, proliferation, and survival, thereby…”
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  7. 7

    Polymerization-Induced Self-Assembly of Block Copolymer Nano-objects via RAFT Aqueous Dispersion Polymerization by Warren, Nicholas J, Armes, Steven P

    Published in Journal of the American Chemical Society (23-07-2014)
    “…In this Perspective, we discuss the recent development of polymeriz­ation-induced self-assembly mediated by reversible addition–fragmentation chain transfer…”
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  8. 8

    New insights into the regulation of T cells by γ c family cytokines by Leonard, Warren J, Rochman, Yrina, Spolski, Rosanne

    Published in Nature reviews. Immunology (01-07-2009)
    “…Key Points The common cytokine receptor γ-chain (γ c ) family of cytokines consists of interleukin-2 (IL-2), IL-4, IL-7, IL-9, IL-15 and IL-21, each of which…”
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  9. 9

    The Fundamental Theorem of Natural Selection: the End of a Story by Ewens, Warren J

    Published in Evolution (01-05-2024)
    “…The direction of research in population genetics theory is currently, and correctly, retrospec- tive, that is directed towards the past. What events in the…”
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  10. 10

    New insights into the regulation of T cells by gamma(c) family cytokines by Rochman, Yrina, Spolski, Rosanne, Leonard, Warren J

    Published in Nature reviews. Immunology (01-07-2009)
    “…Common cytokine receptor gamma-chain (gamma(c)) family cytokines have crucial roles in the development, proliferation, survival and differentiation of multiple…”
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  11. 11

    Deep Learning Methods for Improved Decoding of Linear Codes by Nachmani, Eliya, Marciano, Elad, Lugosch, Loren, Gross, Warren J., Burshtein, David, Be'ery, Yair

    “…The problem of low complexity, close to optimal, channel decoding of linear codes with short to moderate block length is considered. It is shown that deep…”
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  12. 12

    Fast Polar Decoders: Algorithm and Implementation by Sarkis, Gabi, Giard, Pascal, Vardy, Alexander, Thibeault, Claude, Gross, Warren J.

    “…Polar codes provably achieve the symmetric capacity of a memoryless channel while having an explicit construction. The adoption of polar codes however, has…”
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  13. 13

    Tricuspid Valve Dysfunction Following Pacemaker or Cardioverter-Defibrillator Implantation by Chang, James D., MD, Manning, Warren J., MD, Ebrille, Elisa, MD, Zimetbaum, Peter J., MD

    “…Abstract The potential for cardiac implantable electronic device leads to interfere with tricuspid valve (TV) function has gained increasing recognition as…”
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  14. 14

    Molecular basis of the human ribosomopathy Shwachman-Diamond syndrome by Warren, Alan J.

    Published in Advances in biological regulation (01-01-2018)
    “…Mutations that target the ubiquitous process of ribosome assembly paradoxically cause diverse tissue-specific disorders (ribosomopathies) that are often…”
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  15. 15

    Interleukin-21: basic biology and implications for cancer and autoimmunity by Spolski, Rosanne, Leonard, Warren J

    Published in Annual review of immunology (01-01-2008)
    “…Interleukin-21 (IL-21), a potent immunomodulatory four-alpha-helical-bundle type I cytokine, is produced by NKT and CD4(+) T cells and has pleiotropic effects…”
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  16. 16

    Biosynthesis of the modified tetrapyrroles—the pigments of life by Bryant, Donald A., Hunter, C. Neil, Warren, Martin J.

    Published in The Journal of biological chemistry (15-05-2020)
    “…Modified tetrapyrroles are large macrocyclic compounds, consisting of diverse conjugation and metal chelation systems and imparting an array of colors to the…”
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  17. 17

    Strategies to therapeutically modulate cytokine action by Leonard, Warren J., Lin, Jian-Xin

    Published in Nature reviews. Drug discovery (01-10-2023)
    “…Cytokines are secreted or membrane-presented molecules that mediate broad cellular functions, including development, differentiation, growth and survival…”
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  18. 18

    Improved Bit-Flipping Algorithm for Successive Cancellation Decoding of Polar Codes by Ercan, Furkan, Condo, Carlo, Gross, Warren J.

    Published in IEEE transactions on communications (01-01-2019)
    “…The interest in polar codes has been increasing significantly since their adoption for use in the 5 th generation wireless systems standard. Successive…”
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  19. 19

    Aromatherapy, botanicals, and essential oils in acne by Winkelman, Warren J., MD, PhD

    Published in Clinics in dermatology (01-05-2018)
    “…AbstractComplementary and alternative medicine approaches are popular among some patient segments due to the perception that they are “natural” and thus are…”
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  20. 20

    The γc Family of Cytokines: Basic Biology to Therapeutic Ramifications by Leonard, Warren J., Lin, Jian-Xin, O'Shea, John J.

    Published in Immunity (Cambridge, Mass.) (16-04-2019)
    “…The common cytokine receptor γ chain, γc, is a component of the receptors for interleukin-2 (IL-2), IL-4, IL-7, IL-9, IL-15, and IL-21. Mutation of the gene…”
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