Search Results - "WARREN, Cirle A"

Drug Repurposing of the Alcohol Abuse Medication Disulfiram as an Anti-Parasitic Agent by Shirley, Debbie-Ann, Sharma, Ishrya, Warren, Cirle A, Moonah, Shannon

“…Parasitic infections contribute significantly to worldwide morbidity and mortality. Antibiotic treatment is essential for managing patients infected with these…”
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Interaction of Clostridioides difficile infection with frailty and cognition in the elderly: a narrative review by Fernandez-Cotarelo, Maria-Jose, Jackson-Akers, Jasmine Y, Nagy-Agren, Stephanie E, Warren, Cirle A

“…Clostridioides difficile infection (CDI) is the leading cause of antibiotic-related diarrhea and healthcare-associated infections, affecting in particular…”
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Teaching old mice new tricks: the utility of aged mouse models of C. difficile infection to study pathogenesis and rejuvenate immune response by Shin, Jae Hyun, Pawlowski, Sean W., Warren, Cirle A.

“…Clostridioides difficile is a serious problem for the aging population. Aged mouse model of C. difficile infection (CDI) has emerged as a valuable tool to…”
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Role of Pannexin-1-P2X7R signaling on cell death and pro-inflammatory mediator expression induced by Clostridioides difficile toxins in enteric glia by Loureiro, Andrea V., Moura-Neto, Lauro I., Martins, Conceição S., Silva, Pedro I. M., Lopes, Matheus B.S., Leitão, Renata F. C., Coelho-Aguiar, Juliana M., Moura-Neto, Vivaldo, Warren, Cirle A., Costa, Deiziane V.S., Brito, Gerly A. C.

“…Clostridioides difficile ( C. difficile) produces toxins A (TcdA) and B (TcdB), both associated with intestinal damage and diarrhea. Pannexin-1 (Panx1)…”
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Adenosine receptors differentially mediate enteric glial cell death induced by Clostridioides difficile Toxins A and B by Costa, Deiziane V S, Shin, Jae H, Goldbeck, Sophia M, Bolick, David T, Mesquita, Flavio S, Loureiro, Andrea V, Rodrigues-Jesus, Mônica J, Brito, Gerly A C, Warren, Cirle A

“…Increased risk of intestinal dysfunction has been reported in patients after infection (CDI). Enteric glial cells (EGCs), a component of the enteric nervous…”
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Alanyl-glutamine supplementation for Clostridioides difficile infection treatment (ACT): a double-blind randomised controlled trial study protocol by Warren, Cirle A, Shin, Jae Hyun, Bansal, Ekta N, Costa, Deiziane V D S, Wang, Xin Qun, Wu, Martin, Swann, Jonathan R, Behm, Brian W, Targonski, Paul V, Archbald-Pannone, Laurie

“…IntroductionClostridioides difficile is the leading cause of healthcare-associated infections in the USA, with an estimated 1 billion dollars in excess cost to…”
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Rapid in Vitro Assessment of Clostridioides difficile Inhibition by Probiotics Using Dielectrophoresis to Quantify Cell Structure Alterations by Moore, John H, Honrado, Carlos, Stagnaro, Victoria, Kolling, Glynis, Warren, Cirle A, Swami, Nathan S

“…Clostridioides difficile (C. difficile) infection (CDI) is the primary cause of nosocomial antibiotic-associated diarrhea, with high recurrence rates following…”
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S100B Inhibition Attenuates Intestinal Damage and Diarrhea Severity During Clostridioides difficile Infection by Modulating Inflammatory Response by Costa, Deiziane V S, Moura-Neto, Vivaldo, Bolick, David T, Guerrant, Richard L, Fawad, Jibraan A, Shin, Jae H, Medeiros, Pedro H Q S, Ledwaba, Solanka E, Kolling, Glynis L, Martins, Conceição S, Venkataraman, Venkat, Warren, Cirle A, Brito, Gerly A C

“…The involvement of the enteric nervous system, which is a source of S100B, in ( ) infection (CDI) is poorly understood although intestinal motility…”
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Vancomycin Treatment's Association with Delayed Intestinal Tissue Injury, Clostridial Overgrowth, and Recurrence of Clostridium difficile Infection in Mice by WARREN, Cirle A, OPSTAL, Edward J. Van, RIGGINS, Mary S, YUESHENG LI, MOORE, John H, KOLLING, Glynis L, GUERRANT, Richard L, HOFFMAN, Paul S

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Novel In Vitro and In Vivo Models and Potential New Therapeutics to Break the Vicious Cycle of Cryptosporidium Infection and Malnutrition by Costa, Lourrany B., Noronha, Francisco Jose, Roche, James K., Sevilleja, Jesus Emmanuel, Warren, Cirle A., Oriá, Reinaldo, Lima, Aldo, Guerrant, Richard L.

“…Background. Although several animal models of cryptosporidiosis have been reported, most involve genetically or pharmacologically immune-suppressed hosts…”
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Role of Leptin-Mediated Colonic Inflammation in Defense against Clostridium difficile Colitis by Madan, Rajat, Guo, Xiaoti, Naylor, Caitlin, Buonomo, Erica L, Mackay, Donald, Noor, Zannatun, Concannon, Patrick, Scully, Kenneth W, Pramoonjago, Patcharin, Kolling, Glynis L, Warren, Cirle A, Duggal, Priya, Petri, Jr, William A

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Myeloperoxidase as a biomarker for intestinal-brain axis dysfunction induced by malnutrition and Cryptosporidium infection in weanling mice by Oriá, Reinaldo B., Costa, Deiziane V.S., de Medeiros, Pedro Henrique Q.S., Roque, Cássia R., Dias, Ronaldo P., Warren, Cirle A., Bolick, David T., Guerrant, Richard L.

“…Cryptosporidiosis is a waterborne protozoal infection that may cause life-threatening diarrhea in undernourished children living in unsanitary environments…”
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Amixicile, a Novel Inhibitor of Pyruvate:Ferredoxin Oxidoreductase, Shows Efficacy against Clostridium difficile in a Mouse Infection Model by WARREN, Cirle A, VAN OPSTAL, Edward, MACDONALD, Timothy L, HOFFMAN, Paul S, BALLARD, T. Eric, KENNEDY, Andrew, XIA WANG, RIGGINS, Mary, OLEKHNOVICH, Igor, WARTHAN, Michelle, KOLLING, Glynis L, GUERRANT, Richard L

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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In Vivo Physiological and Transcriptional Profiling Reveals Host Responses to Clostridium difficile Toxin A and Toxin B by D'Auria, Kevin M, Kolling, Glynis L, Donato, Gina M, Warren, Cirle A, Gray, Mary C, Hewlett, Erik L, Papin, Jason A

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Defined Nutrient Diets Alter Susceptibility to Clostridium difficile Associated Disease in a Murine Model by Moore, John H, Pinheiro, Caio C D, Zaenker, Edna I, Bolick, David T, Kolling, Glynis L, van Opstal, Edward, Noronha, Francisco J D, De Medeiros, Pedro H Q S, Rodriguez, Raphael S, Lima, Aldo A, Guerrant, Richard L, Warren, Cirle A

“…Clostridium difficile is a major identifiable and treatable cause of antibiotic-associated diarrhea. Poor nutritional status contributes to mortality through…”
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Apolipoprotein E plays a key role against cryptosporidial infection in transgenic undernourished mice by Azevedo, Orleâncio G R, Bolick, David T, Roche, James K, Pinkerton, Relana F, Lima, Aldo A M, Vitek, Michael P, Warren, Cirle A, Oriá, Reinaldo B, Guerrant, Richard L

“…Apolipoliprotein E (apoE), a critical targeting protein in lipid homeostasis, has been found to have immunoinflammatory effects on murine models of infection…”
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Delirium and other clinical factors with Clostridium difficile infection that predict mortality in hospitalized patients by Archbald-Pannone, Laurie R., MD, MPH, McMurry, Timothy L., PhD, Guerrant, Richard L., MD, Warren, Cirle A., MD

“…Background Clostridium difficile infection (CDI) severity has increased, especially among hospitalized older adults. We evaluated clinical factors to predict…”
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Modeling the role of peroxisome proliferator-activated receptor γ and microRNA-146 in mucosal immune responses to Clostridium difficile by Viladomiu, Monica, Hontecillas, Raquel, Pedragosa, Mireia, Carbo, Adria, Hoops, Stefan, Michalak, Pawel, Michalak, Katarzyna, Guerrant, Richard L, Roche, James K, Warren, Cirle A, Bassaganya-Riera, Josep

“…Clostridium difficile is an anaerobic bacterium that has re-emerged as a facultative pathogen and can cause nosocomial diarrhea, colitis or even death…”
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Cryptosporidium Priming Is More Effective than Vaccine for Protection against Cryptosporidiosis in a Murine Protein Malnutrition Model by Bartelt, Luther A, Bolick, David T, Kolling, Glynis L, Roche, James K, Zaenker, Edna I, Lara, Ana M, Noronha, Francisco Jose, Cowardin, Carrie A, Moore, John H, Turner, Jerrold R, Warren, Cirle A, Buck, Gregory A, Guerrant, Richard L

“…Cryptosporidium is a major cause of severe diarrhea, especially in malnourished children. Using a murine model of C. parvum oocyst challenge that recapitulates…”
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Pyridopyrimidine derivatives as inhibitors of cyclic nucleotide synthesis: Application for treatment of diarrhea by Kots, Alexander Y, Choi, Byung-Kwon, Estrella-Jimenez, Maria E, Warren, Cirle A, Gilbertson, Scott R, Guerrant, Richard L, Murad, Ferid

“…Acute secretory diarrhea induced by infection with enterotoxigenic strains of Escherichia coli involves binding of stable toxin (STa) to its receptor on the…”
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