Search Results - "WARNOCK, D. G"

Fabry disease: progression of nephropathy, and prevalence of cardiac and cerebrovascular events before enzyme replacement therapy by Schiffmann, Raphael, Warnock, David G., Banikazemi, Maryam, Bultas, Jan, Linthorst, Gabor E., Packman, Seymour, Sorensen, Sven Asger, Wilcox, William R., Desnick, Robert J.

“…Background. In Fabry disease, progressive glycolipid accumulation leads to organ damage and early demise, but the incidence of renal, cardiac and…”
Get full text

Liddle's Syndrome Revisited -- A Disorder of Sodium Reabsorption in the Distal Tubule by Botero-Velez, Mauricio, Curtis, John J, Warnock, David G

“…In 1963 Liddle et al. 1 described a disorder that simulated primary aldosteronism, characterized by severe hypertension and hypokalemia but with negligible…”
Get full text

Renal outcomes of agalsidase beta treatment for Fabry disease: role of proteinuria and timing of treatment initiation by WARNOCK, David G, ORTIZ, Alberto, LEMAY, Roberta, COLE, J. Alexander, SVARSTAD, Einar, WALDEK, Stephen, GERMAIN, Dominique P, WANNER, Christoph, MAUER, Michael, LINTHORST, Gabor E, OLIVEIRA, Joao P, SERRA, Andreas L, MARODI, László, MIGNANI, Renzo, VUJKOVAC, Bojan, BEITNER-JOHNSON, Dana

“…The purpose of this study was to identify determinants of renal disease progression in adults with Fabry disease during treatment with agalsidase beta. Renal…”
Get full text

Liddle syndrome: An autosomal dominant form of human hypertension by Warnock, David G.

Get full text

Kidney disease in the first-degree relatives of African-Americans with hypertensive end-stage renal disease by Bergman, S, Key, B O, Kirk, K A, Warnock, D G, Rostant, S G

“…The incidence of treated end-stage renal disease (ESRD) in the United States is four times more frequent in African-Americans (AAs) than in whites. This is…”
Get more information

Heterologous expression of rat NHE4: a highly amiloride-resistant Na+/H+ exchanger isoform by Chambrey, R, Achard, J M, Warnock, D G

“…Molecular cloning and expression have previously defined three members of the Na+/H+ exchanger (NHE) gene family NHE1 and NHE2 are sensitive to inhibition by…”
Get full text

Membranous glomerulopathy in an adult patient with X-linked agammaglobulinemia receiving intravenous gammaglobulin by Endo, L M, Giannobile, J V, Dobbs, A K, Foote, J B, Szymanska, E, Warnock, D G, Cook, W J, Conley, M E, Schroeder, H W

“…Immune complex deposition in the subepithelial zone of glomerular capillaries can lead to membranous glomerulopathy. To present the case of a 23-year-old man…”
Get full text

Regulation by PKC isoforms of Na(+)/H(+) exchanger in luminal membrane vesicles isolated from cortical tubules by Karim, Z G, Chambrey, R, Chalumeau, C, Defontaine, N, Warnock, D G, Paillard, M, Poggioli, J

“…The present study was designed to determine the Na/H exchanger isoforms present in luminal membrane vesicles (LMV) isolated from rat kidney cortical tubule…”
Get full text

Rapid redistribution and inhibition of renal sodium transporters during acute pressure natriuresis by Zhang, Y, Mircheff, A K, Hensley, C B, Magyar, C E, Warnock, D G, Chambrey, R, Yip, K P, Marsh, D J, Holstein-Rathlou, N H, McDonough, A A

“…Acute arterial hypertension provokes a rapid decrease in proximal tubule (PT) Na+ reabsorption, increasing flow to the macula densa, the signal for…”
Get full text

Low-renin and nonmodulating essential hypertension by WARNOCK, D. G

Get full text

Activation of ion transport systems during cell volume regulation by Eveloff, J L, Warnock, D G

“…This review discusses the activation of transport pathways during volume regulation, including their characteristics, the possible biochemical pathways that…”
Get full text

Mutational analysis of transmembrane histidines in the amiloride-sensitive Na+/H+ exchanger by Wang, D, Balkovetz, D F, Warnock, D G

“…The histidine-reactive reagent, diethyl pyrocarbonate (DEPC) inhibits the human amiloride-sensitive Na+/H+ exchanger (NHE1) in stably transfected fibroblasts…”
Get full text

Liddle's disease: abnormal regulation of amiloride-sensitive Na+ channels by beta-subunit mutation by Bubien, J K, Ismailov, I I, Berdiev, B K, Cornwell, T, Lifton, R P, Fuller, C M, Achard, J M, Benos, D J, Warnock, D G

“…Liddle's disease is an autosomal dominant genetic disorder characterized by severe low renin hypertension ("pseudoaldosteronism") that has been genetically…”
Get full text

Prevalence and prognosis of unrecognized myocardial infarctions in chronic kidney disease by RIZK, Dana V, GUTIERREZ, Orlando, LEVITAN, Emily B, MCCLELLAN, William M, SAFFORD, Monika, SOLIMAN, Elsayed Z, WARNOCK, David G, MUNTNER, Paul

“…Unrecognized myocardial infarctions (UMIs) are common in the general population but have not been well studied in patients with chronic kidney disease (CKD)…”
Get full text

Evidence for an amiloride-insensitive Na+/H+ exchanger in rat renal cortical tubules by Chambrey, R, Achard, J M, St John, P L, Abrahamson, D R, Warnock, D G

“…We have characterized the Na+/H+ exchanger (NHE) isoforms expressed in rat renal cortical tubule fragments. Amiloride sensitivity of the Na(+)-dependent…”
Get full text

Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN) by Fogo, Agnes B., Bostad, Leif, Svarstad, Einar, Cook, William J., Moll, Solange, Barbey, Federic, Geldenhuys, Laurette, West, Michael, Ferluga, Dusan, Vujkovac, Bojan, Howie, Alexander J., Burns, Áine, Reeve, Roy, Waldek, Stephen, Noël, Laure-Hélène, Grünfeld, Jean-Pierre, Valbuena, Carmen, Oliveira, João Paulo, Müller, Justus, Breunig, Frank, Zhang, Xiao, Warnock, David G.

“…Background. In Fabry nephropathy, alpha-galactosidase deficiency leads to accumulation of glycosphingolipids in all kidney cell types, proteinuria and…”
Get full text

Parallel adaptation of the rabbit renal cortical sodium/proton antiporter and sodium/bicarbonate cotransporter in metabolic acidosis and alkalosis by AKIBA, T, ROCCO, V. K, WARNOCK, D. G

“…Recent studies have shown that the bicarbonate reabsorptive capacity of the proximal tubule is increased in metabolic acidosis. For net bicarbonate…”
Get full text

Amiloride-sensitive sodium conductance in human B lymphoid cells by Bubien, J K, Warnock, D G

“…The Na+ conductance of RPMI 8226 human B lymphoblastoid cells was examined using whole cell patch clamp. When the bath solution contained RPMI 1640 and the…”
Get full text

Renal Na+/H+ exchanger isoforms and their regulation by thyroid hormone by Azuma, K K, Balkovetz, D F, Magyar, C E, Lescale-Matys, L, Zhang, Y, Chambrey, R, Warnock, D G, McDonough, A A

“…Na+ crosses the luminal membrane of the proximal tubule primarily via Na+/H+ exchange (NHE), and NHE activity is influenced by thyroid status. Pharmacological,…”
Get full text

Genetic association of 11β-hydroxysteroid dehydrogenase type 2 (HSD11B2) flanking microsatellites with essential hypertension in blacks by WATSON, B. JR, BERGMAN, S. M, MYRACLE, A, CALLEN, D. F, ACTON, R. T, WARNOCK, D. G

“…11 beta-Hydroxysteroid dehydrogenase type 2 (11 beta-HSD2) specifically modulates access of the mineralocorticoid aldosterone to the kidney mineralocorticoid…”
Get full text