Search Results - "WARLTIER, D. C"

Ketamine attenuates post-operative cognitive dysfunction after cardiac surgery by HUDETZ, J. A., IQBAL, Z., GANDHI, S. D., PATTERSON, K. M., BYRNE, A. J., HUDETZ, A. G., PAGEL, P. S., WARLTIER, D. C.

“…Background: Post‐operative cognitive dysfunction (POCD) commonly occurs after cardiac surgery. Ketamine exerts neuroprotective effects after cerebral ischemia…”
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Isoflurane protects cardiomyocytes and mitochondria by immediate and cytosol‐independent action at reperfusion by Pravdic, D, Mio, Y, Sedlic, F, Pratt, PF, Warltier, DC, Bosnjak, ZJ, Bienengraeber, M

“…Background and purpose:  The volatile anaesthetic isoflurane protects the heart from ischaemia and reperfusion (I/R) injury when applied at the onset of…”
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Approaches to the prevention of perioperative myocardial ischemia by WARLTIER, D. C, PAGEL, P. S, KERSTEN, J. R

“…Goals for the perioperative management of patients with coronary artery disease include: * Prevent increases in sympathetic nervous system activity: reduce…”
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Sarcolemmal and mitochondrial adenosine triphosphate-dependent potassium channels : Mechanism of desflurane-induced cardioprotection by TOLLER, W. G, GROSS, E. R, KERSTEN, J. R, PAGEL, P. S, GROSS, G. J, WARLTIER, D. C

“…Volatile anesthetic-induced preconditioning is mediated by adenosine triphosphate-dependent potassium (KATP) channels; however, the subcellular location of…”
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Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs by TOLLER, W. G, KERSTEN, J. R, PAGEL, P. S, HETTRICK, D. A, WARLTIER, D. C

“…Recent evidence indicates that volatile anesthetics exert protective effects during myocardial ischemia and reperfusion. The authors tested the hypothesis that…”
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Influence of levosimendan, pimobendan, and milrinone on the regional distribution of cardiac output in anaesthetized dogs by Pagel, Paul S., Hettrick, Douglas A., Warltier, David C.

“…1 The distribution of cardiac output during administration of levosimendan, a new myofilament calcium sensitizer, is unknown. We examined and compared the…”
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Beta-adrenergic-blocking drugs: incredibly useful, incredibly underutilized by Warltier, D C

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Levosimendan Enhances Cardiac Performance After Cardiopulmonary Bypass: A Prospective, Randomized Placebo-Controlled Trial by Nijhawan, Niraj, Nicolosi, Alfred C, Montgomery, Matthew W, Aggarwal, Anil, Pagel, Paul S, Warltier, David C

“…Levosimendan is a new myofilament calcium (Ca) sensitizer that increases myocardial contractility by stabilizing the Ca-bound conformation of troponin C. We…”
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Mechanisms of postischemic contractile dysfunction by Gross, Garrett J, Kersten, Judy R, Warltier, David C

“…Prolonged reversible postischemic contractile dysfunction that follows single or multiple brief periods of regional or global ischemia has been termed “stunned…”
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Isoflurane preconditions myocardium against infarction via activation of inhibitory guanine nucleotide binding proteins by TOLLER, W. G, KERSTEN, J. R, GROSS, E. R, PAGEL, P. S, WARLTIER, D. C

“…Isoflurane-induced myocardial protection during ischemia is mediated by adenosine triphosphate-regulated potassium (KATP) channels; however, the intracellular…”
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Mechanism of myocardial protection by isoflurane : Role of adenosine triphosphate-regulated potassium (KATP) channels by KERSTEN, J. R, SCHMELING, T. J, HETTRICK, D. A, PAGEL, P. S, GROSS, G. J, WARLTIER, D. C

“…The mechanism of the protective actions of volatile anesthetics in ischemic myocardium has not been clearly elucidated. The role of myocardial adenosine…”
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Negative inotropic effects of propofol as evaluated by the regional preload recruitable stroke work relationship in chronically instrumented dogs by PAGEL, P. S, WARLTIER, D. C

“…Propofol anesthesia often is associated with marked decreases in arterial blood pressure. Previous investigations in vivo have provided conflicting reasons for…”
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Intracoronary Levosimendan Enhances Contractile Function of Stunned Myocardium by Jamali, Iyad N., Kersten, Judy R., Pagel, Paul S., Hettrick, Douglas A., Warltier, David C.

“…A decrease in myofilament sensitivity to Ca has been proposed as a mechanism for reversible contractile dysfunction after ischemia and reperfusion.The direct…”
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Activation of adenosine triphosphate-regulated potassium channels mediation of cellular and organ protection by KERSTEN, J. R, GROSS, G. J, PAGEL, P. S, WARLTIER, D. C

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Multifactorial basis for coronary collateralization : a complex adaptive response to ischemia by KERSTEN, J. R, PAGEL, P. S, CHILIAN, W. M, WARLTIER, D. C

“…Angiogenesis and vasculogenesis are adaptive responses of the coronary collateral circulation to myocardial ischemia. This review focuses on the concerted…”
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Cardiovascular effects of xenon in isoflurane-anesthetized Dogs with dilated cardiomyopathy by HETTRICK, D. A, PAGEL, P. S, KERSTEN, J. R, TESSMER, J. P, BOSNJAK, Z. J, GEORGIEFF, M, WARLTIER, D. C

“…Clinical interest in xenon has been rekindled recently by new recycling systems that have decreased its relative cost. The cardiovascular effects of xenon were…”
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Role of adenosine in isoflurane-induced cardioprotection by KERSTEN, J. R, ORTH, K. G, PAGEL, P. S, MEI, D. A, GROSS, G. J, WARLTIER, D. C

“…This investigation tested the hypothesis that adenosine (A1) receptor blockade modulates the cardioprotective effects of isoflurane. Hemodynamics and…”
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Comparison of the systemic and coronary hemodynamic actions of desflurane, isoflurane, halothane, and enflurane in the chronically instrumented dog by PAGEL, P. S, KAMPINE, J. P, SCHMELING, W. T, WARLTIER, D. C

“…The systemic and coronary hemodynamic effects of desflurane were compared to those of isoflurane, halothane, and enflurane in chronically instrumented dogs…”
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Recovery of contractile function of stunned myocardium in chronically instrumented dogs is enhanced by halothane or isoflurane by WARLTIER, D. C, AL-WATHIQUI, M. H, KAMPINE, J. P, SCHMELING, W. T

“…Following brief periods (5-15 min) of total coronary artery occlusion and subsequent reperfusion, despite an absence of tissue necrosis, a decrement in…”
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Desflurane and isoflurane produce similar alterations in systemic and pulmonary hemodynamics and arterial oxygenation in patients undergoing one-lung ventilation during thoracotomy by PAGEL, P. S, FU, J. L, DAMASK, M. C, DAVIS, R. F, SAMUELSON, P. N, HOWIE, M. B, WARLTIER, D. C

“…We tested the hypothesis that desflurane (DES) and isoflurane (ISO) produce similar effects on systemic and pulmonary hemodynamics and arterial oxygenation…”
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