Search Results - "WARD, JOHN M."

Aggregatibacter (Actinobacillus) actinomycetemcomitans: a triple A periodontopathogen? by Henderson, Brian, Ward, John M., Ready, Derren

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Enzyme catalysed Pictet-Spengler formation of chiral 1,1’-disubstituted- and spiro-tetrahydroisoquinolines by Lichman, Benjamin R., Zhao, Jianxiong, Hailes, Helen C., Ward, John M.

“…The Pictet–Spengler reaction (PSR) involves the condensation and ring closure between a β-arylethylamine and a carbonyl compound. The combination of dopamine…”
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Enzymatic and Chemoenzymatic Three‐Step Cascades for the Synthesis of Stereochemically Complementary Trisubstituted Tetrahydroisoquinolines by Erdmann, Vanessa, Lichman, Benjamin R., Zhao, Jianxiong, Simon, Robert C., Kroutil, Wolfgang, Ward, John M., Hailes, Helen C., Rother, Dörte

“…Chemoenzymatic and enzymatic cascade reactions enable the synthesis of complex stereocomplementary 1,3,4‐trisubstituted tetrahydroisoquinolines (THIQs) with…”
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Two Steps in One Pot: Enzyme Cascade for the Synthesis of Nor(pseudo)ephedrine from Inexpensive Starting Materials by Sehl, Torsten, Hailes, Helen C., Ward, John M., Wardenga, Rainer, von Lieres, Eric, Offermann, Heike, Westphal, Robert, Pohl, Martina, Rother, Dörte

“…Two steps in one pot: An enzyme cascade consisting of a lyase and an (R)‐ or (S)‐selective ω‐transaminase (TA) provides (1R,2R)‐norpseudoephedrine and…”
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Virus lasers for biological detection by Hales, John E., Matmon, Guy, Dalby, Paul A., Ward, John M., Aeppli, Gabriel

“…The selective amplification of DNA in the polymerase chain reaction is used to exponentially increase the signal in molecular diagnostics for nucleic acids,…”
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Transport Function of Rice Amino Acid Permeases (AAPs) by Taylor, Margaret R, Reinders, Anke, Ward, John M

“…The transport function of four rice (Oryza sativa) amino acid permeases (AAPs), OsAAP1 (Os07g04180), OsAAP3 (Os06g36180), OsAAP7 (Os05g34980) and OsAAP16…”
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Molecular Evolution of Plant AAP and LHT Amino Acid Transporters by Tegeder, Mechthild, Ward, John M

“…Nitrogen is an essential mineral nutrient and it is often transported within living organisms in its reduced form, as amino acids. Transport of amino acids…”
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A cell engineering approach to enzyme-based fed-batch fermentation by Sibley, Michael, Ward, John M

“…A fundamental problem associated with E. coli fermentations is the difficulty in achieving high cell densities in batch cultures, attributed in large part to…”
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Production of indigo by recombinant bacteria by Linke, Julia A., Rayat, Andrea, Ward, John M.

“…Indigo is an economically important dye, especially for the textile industry and the dyeing of denim fabrics for jeans and garments. Around 80,000 tonnes of…”
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Isolation of Radiation-Resistant Bacteria from Mars Analog Antarctic Dry Valleys by Preselection, and the Correlation between Radiation and Desiccation Resistance by Musilova, Michaela, Wright, Gary, Ward, John M, Dartnell, Lewis R

“…Extreme radiation-resistant microorganisms can survive doses of ionizing radiation far greater than are present in the natural environment. Radiation…”
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Enzymatic synthesis of benzylisoquinoline alkaloids using a parallel cascade strategy and tyrosinase variants by Wang, Yu, Subrizi, Fabiana, Carter, Eve M., Sheppard, Tom D., Ward, John M., Hailes, Helen C.

“…Benzylisoquinoline alkaloid derived pharmaceuticals are widely applied in modern medicines. Recent studies on the microbial production of benzylisoquinolines…”
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Arabidopsis Sucrose Transporter AtSUC1 Is Important for Pollen Germination and Sucrose-Induced Anthocyanin Accumulation by Sivitz, Alicia B, Reinders, Anke, Ward, John M

“…The Arabidopsis (Arabidopsis thaliana) sucrose transporter AtSUC1 (At1g71880) is highly expressed in pollen; however, its function has remained unknown. Here,…”
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Evolution of plant sucrose uptake transporters by Reinders, Anke, Sivitz, Alicia B, Ward, John M

“…In angiosperms, sucrose uptake transporters (SUTs) have important functions especially in vascular tissue. Here we explore the evolutionary origins of SUTs by…”
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Evolution of Electrogenic Ammonium Transporters (AMTs) by McDonald, Tami R, Ward, John M

“…The ammonium transporter gene family consists of three main clades, AMT, MEP, and Rh. The evolutionary history of the AMT/MEP/Rh gene family is characterized…”
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Novel transaminases from thermophiles: from discovery to application by Cárdenas‐Fernández, Max, Sinclair, Oliver, Ward, John M.

“…Summary Transaminases (TAs) are promising biocatalysts for chiral amine synthesis; however, only few thermophilic TAs have been described to date. In this…”
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pET expression vector customized for efficient seamless cloning by Dobrijevic, Dragana, Nematollahi, Lily A, Hailes, Helen C, Ward, John M

“…Here we present a modification of the widely used pET29 expression vector for use in rapid and straightforward parallel cloning via a gene replacement and…”
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Impaired Function of the Tonoplast-Localized Sucrose Transporter in Rice, OsSUT2, Limits the Transport of Vacuolar Reserve Sucrose and Affects Plant Growth by Eom, Joon-Seob, Cho, Jung-Il, Reinders, Anke, Lee, Sang-Won, Yoo, Youngchul, Tuan, Pham Quoc, Choi, Sang-Bong, Bang, Geul, Park, Youn-Il, Cho, Man-Ho, Bhoo, Seong Hee, An, Gynheung, Hahn, Tae-Ryong, Ward, John M., Jeon, Jong-Seong

“…Physiological functions of sucrose (Suc) transporters (SUTs) localized to the tonoplast in higher plants are poorly understood. We here report the isolation…”
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Liquid-microjet photoelectron spectroscopy of the green fluorescent protein chromophore by Tau, Omri, Henley, Alice, Boichenko, Anton N., Kleshchina, Nadezhda N., Riley, River, Wang, Bingxing, Winning, Danielle, Lewin, Ross, Parkin, Ivan P., Ward, John M., Hailes, Helen C., Bochenkova, Anastasia V., Fielding, Helen H.

“…Green fluorescent protein (GFP), the most widely used fluorescent protein for in vivo monitoring of biological processes, is known to undergo photooxidation…”
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One-pot, two-step transaminase and transketolase synthesis of l-gluco-heptulose from l-arabinose by Bawn, Maria, Subrizi, Fabiana, Lye, Gary J., Sheppard, Tom D., Hailes, Helen C., Ward, John M.

“…•Characterisation of new thermostable transketolase and transaminase enzymes towards L-arabinose and L-serine.•Explored novel thermostable transaminases to…”
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The Molecular Dialog between Flowering Plant Reproductive Partners Defined by SNP-Informed RNA-Sequencing by Leydon, Alexander R., Weinreb, Caleb, Venable, Elena, Reinders, Anke, Ward, John M., Johnson, Mark A.

“…The molecular interactions between reproductive cells are critical for determining whether sexual reproduction between individuals results in fertilization and…”
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