Search Results - "WARCZOK, Katarzyna E"

Active and Repressive Chromatin Are Interspersed without Spreading in an Imprinted Gene Cluster in the Mammalian Genome by Regha, Kakkad, Sloane, Mathew A., Huang, Ru, Pauler, Florian M., Warczok, Katarzyna E., Melikant, Balázs, Radolf, Martin, Martens, Joost H.A., Schotta, Gunnar, Jenuwein, Thomas, Barlow, Denise P.

“…The Igf2r imprinted cluster is an epigenetic silencing model in which expression of a ncRNA silences multiple genes in cis. Here, we map a 250 kb region in…”
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An in vitro ES cell imprinting model shows that imprinted expression of the Igf2r gene arises from an allele-specific expression bias by Latos, Paulina A, Stricker, Stefan H, Steenpass, Laura, Pauler, Florian M, Huang, Ru, Senergin, Basak H, Regha, Kakkad, Koerner, Martha V, Warczok, Katarzyna E, Unger, Christine, Barlow, Denise P

“…Genomic imprinting is an epigenetic process that results in parental-specific gene expression. Advances in understanding the mechanism that regulates imprinted…”
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Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo by Hudson, Quanah J., Seidl, Christine I.M., Kulinski, Tomasz M., Huang, Ru, Warczok, Katarzyna E., Bittner, Romana, Bartolomei, Marisa S., Barlow, Denise P.

“…A subset of imprinted genes in the mouse have been reported to show imprinted expression that is restricted to the placenta, a short-lived extra-embryonic…”
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Identification of the human homolog of the imprinted mouse Air non-coding RNA by Yotova, Iveta Y., Vlatkovic, Irena M., Pauler, Florian M., Warczok, Katarzyna E., Ambros, Peter F., Oshimura, Mitsuo, Theussl, Hans-Christian, Gessler, Manfred, Wagner, Erwin F., Barlow, Denise P.

“…Genomic imprinting is widely conserved amongst placental mammals. Imprinted expression of IGF2R, however, differs between mice and humans. In mice, Igf2r…”
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A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted Airn macro ncRNA promoter by Koerner, Martha V, Pauler, Florian M, Hudson, Quanah J, Santoro, Federica, Sawicka, Anna, Guenzl, Philipp M, Stricker, Stefan H, Schichl, Yvonne M, Latos, Paulina A, Klement, Ruth M, Warczok, Katarzyna E, Wojciechowski, Jacek, Seiser, Christian, Kralovics, Robert, Barlow, Denise P

“…A CpG island (CGI) lies at the 5' end of the Airn macro non-protein-coding (nc) RNA that represses the flanking Igf2r promoter in cis on paternally inherited…”
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Silencing and transcriptional properties of the imprinted Airn ncRNA are independent of the endogenous promoter by Stricker, Stefan H, Steenpass, Laura, Pauler, Florian M, Santoro, Federica, Latos, Paulina A, Huang, Ru, Koerner, Martha V, Sloane, Mathew A, Warczok, Katarzyna E, Barlow, Denise P

“…The Airn macro ncRNA is the master regulator of imprinted expression in the Igf2r imprinted gene cluster where it silences three flanking genes in cis . Airn…”
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Airn Transcriptional Overlap, But Not Its lncRNA Products, Induces Imprinted Igf2r Silencing by Latos, Paulina A., Pauler, Florian M., Koerner, Martha V., Şenergin, H. Başak, Hudson, Quanah J., Stocsits, Roman R., Allhoff, Wolfgang, Stricker, Stefan H., Klement, Ruth M., Warczok, Katarzyna E., Aumayr, Karin, Pasierbek, Pawel, Barlow, Denise P.

“…Mammalian imprinted genes often cluster with long noncoding (lnc) RNAs. Three lncRNAs that induce parental-specific silencing show hallmarks indicating that…”
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Imprinted Igf2r silencing depends on continuous Airn lncRNA expression and is not restricted to a developmental window by Santoro, Federica, Mayer, Daniela, Klement, Ruth M, Warczok, Katarzyna E, Stukalov, Alexey, Barlow, Denise P, Pauler, Florian M

“…The imprinted Airn macro long non-coding (lnc) RNA is an established example of a cis-silencing lncRNA. Airn expression is necessary to initiate…”
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Long-range DNase I hypersensitivity mapping reveals the imprinted Igf2r and Air promoters share cis-regulatory elements by Pauler, Florian M, Stricker, Stefan H, Warczok, Katarzyna E, Barlow, Denise P

“…Epigenetic mechanisms restrict the expression of imprinted genes to one parental allele in diploid cells. At the Igf2r/Air imprinted cluster on mouse…”
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Airn Transcriptional Overlap, But Not Its IncRNA Products, Induces Imprinted Igf2r Silencing by LATOS, Paulina A, PAULER, Florian M, AUMAYR, Karin, PASIERBEK, Pawel, BARLOW, Denise P, KOERNER, Martha V, BASAK SENERGIN, H, HUDSON, Quanah J, STOCSITS, Roman R, ALLHOFF, Wolfgang, STRICKER, Stefan H, KLEMENT, Ruth M, WARCZOK, Katarzyna E

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