Search Results - "WANG, Diane"

Effect of P-glycoprotein (P-gp) Inducers on Exposure of P-gp Substrates: Review of Clinical Drug–Drug Interaction Studies by Elmeliegy, Mohamed, Vourvahis, Manoli, Guo, Cen, Wang, Diane D.

“…Understanding transporter-mediated drug–drug interactions (DDIs) for investigational agents is important during drug development to assess DDI liability, its…”
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Sowing the seeds of multi-genome rice by Wang, Diane R

“…[...]polyploidy has served as a common mode of evolution in flowering plants1. The work opens the door to developing plants that not only can better withstand…”
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Road map for domesticating multi-genome rice using gene editing by Wang, Diane R.

“…Having more than two sets of chromosomes can help plants to adapt and evolve, but generating new crops with this type of genome is challenging. A road map for…”
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An improved 7K SNP array, the C7AIR, provides a wealth of validated SNP markers for rice breeding and genetics studies by Morales, Karina Y, Singh, Namrata, Perez, Francisco Agosto, Ignacio, John Carlos, Thapa, Ranjita, Arbelaez, Juan D, Tabien, Rodante E, Famoso, Adam, Wang, Diane R, Septiningsih, Endang M, Shi, Yuxin, Kretzschmar, Tobias, McCouch, Susan R, Thomson, Michael J

“…Single nucleotide polymorphisms (SNPs) are highly abundant, amendable to high-throughput genotyping, and useful for a number of breeding and genetics…”
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Lung Cancer Heterogeneity and New Strategies for Drug Therapy by Wang, Diane C, Wang, William, Zhu, Bijun, Wang, Xiangdong

“…Lung cancer heterogeneity plays an important role in the development of drug resistance. Comprehensive molecular characterizations of lung cancer can describe…”
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LABA1, a Domestication Gene Associated with Long, Barbed Awns in Wild Rice by Hua, Lei, Wang, Diane R., Tan, Lubin, Fu, Yongcai, Liu, Fengxia, Xiao, Langtao, Zhu, Zuofeng, Fu, Qiang, Sun, Xianyou, Gu, Ping, Cai, Hongwei, McCouch, Susan R., Sun, Chuanqing

“…Common wild rice (Oryza rufipogon), the wild relative of Asian cultivated rice (Oryza sativa), flaunts long, barbed awns, which are necessary for efficient…”
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Genome analyses identify the genetic modification of lung cancer subtypes by Zhang, Yong, Wang, Diane C, Shi, Lin, Zhu, Bijun, Min, Zhihui, Jin, Jianjun

“…Abstract Lung cancer is a highly intricate and heterogeneous disease with genomic diversity in each subtype. Global analyses of gene expression and sequencing…”
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An imputation platform to enhance integration of rice genetic resources by Wang, Diane R., Agosto-Pérez, Francisco J., Chebotarov, Dmytro, Shi, Yuxin, Marchini, Jonathan, Fitzgerald, Melissa, McNally, Kenneth L., Alexandrov, Nickolai, McCouch, Susan R.

“…As sequencing and genotyping technologies evolve, crop genetics researchers accumulate increasing numbers of genomic data sets from various genotyping…”
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Population Pharmacokinetics of Talazoparib in Patients With Advanced Cancer by Yu, Yanke, Durairaj, Chandrasekar, Shi, Haihong, Wang, Diane D.

“…Poly(ADP‐ribose) polymerase (PARP) inhibitors have been developed to treat cancers associated with somatic BRCA mutations and germline genetic aberrations…”
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Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience by Bryce, Clare, Grimes, Zachary, Pujadas, Elisabet, Ahuja, Sadhna, Beasley, Mary Beth, Albrecht, Randy, Hernandez, Tahyna, Stock, Aryeh, Zhao, Zhen, AlRasheed, Mohamed Rizwan, Chen, Joyce, Li, Li, Wang, Diane, Corben, Adriana, Haines, G. Kenneth, Westra, William H., Umphlett, Melissa, Gordon, Ronald E., Reidy, Jason, Petersen, Bruce, Salem, Fadi, Fiel, Maria Isabel, El Jamal, Siraj M., Tsankova, Nadejda M., Houldsworth, Jane, Mussa, Zarmeen, Veremis, Brandon, Sordillo, Emilia, Gitman, Melissa R., Nowak, Michael, Brody, Rachel, Harpaz, Noam, Merad, Miriam, Gnjatic, Sacha, Liu, Wen-Chun, Schotsaert, Michael, Miorin, Lisa, Aydillo Gomez, Teresa A., Ramos-Lopez, Irene, Garcia-Sastre, Adolfo, Donnelly, Ryan, Seigler, Patricia, Keys, Calvin, Cameron, Jennifer, Moultrie, Isaiah, Washington, Kae-Lynn, Treatman, Jacquelyn, Sebra, Robert, Jhang, Jeffrey, Firpo, Adolfo, Lednicky, John, Paniz-Mondolfi, Alberto, Cordon-Cardo, Carlos, Fowkes, Mary E.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical syndrome COVID-19 are causing overwhelming morbidity and mortality…”
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Optimizing benefit/risk in oncology: Review of post-marketing dose optimization and reflections on the road ahead by Soltantabar, Pooneh, Lon, Hoi-Kei, Parivar, Kourosh, Wang, Diane D., Elmeliegy, Mohamed

“…Oncology therapies shifted from chemotherapy to molecularly targeted agents and finally to the era of immune-oncology agents. In contrast to cytotoxic agents,…”
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Discordance Between Child‐Pugh and National Cancer Institute Classifications for Hepatic Dysfunction: Implications on Dosing Recommendations for Oncology Compounds by Elmeliegy, Mohamed, Yang, Derek Z., Salama, Engie, Parivar, Kourosh, Wang, Diane D.

“…Guidance from the U.S. Food and Drug Administration (FDA) and the European Medicines Agency recommends using Child‐Pugh classification for pharmacokinetic…”
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Detection of single cell heterogeneity in cancer by Qian, Mengjia, Wang, Diane C, Chen, Hao, Cheng, Yunfeng

“…Single cell heterogeneity has already been highlighted in cancer classification, diagnosis, and treatment. Recent advanced technologies have gained more…”
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Role of epigenetics in lung cancer heterogeneity and clinical implication by Dong, Nian, Shi, Lin, Wang, Diane C., Chen, Chengshui, Wang, Xiangdong

“…Lung cancer, as a highly heterogeneous disease, can be initiated and progressed through the interaction between permanent genetic mutations and dynamic…”
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Analysis of US Food and Drug Administration Oncology Approvals on the Characterization of Hepatic Impairment Effect and Dosing Recommendations by Yang, Derek Z., Alhadab, Ali, Parivar, Kourosh, Wang, Diane D., Elmeliegy, Mohamed

“…Patients with cancer and advanced hepatic impairment (HI) (i.e., moderate and severe impairment) are often excluded from first‐in‐patient, phase II, and phase…”
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Acute lung injury in patients with COVID‐19 infection by Li, Liyang, Huang, Qihong, Wang, Diane C., Ingbar, David H., Wang, Xiangdong

“…During the 2020 Spring Festival in China, the outbreak of a novel coronavirus, named COVID‐19 by WHO, brought on a worldwide panic. According to the clinical…”
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A tour of 3D genome with a focus on CTCF by Wang, Diane C., Wang, William, Zhang, Linlin, Wang, Xiangdong

“…The complex three-dimensional (3D) structure of the genome plays critical roles in the maintenance of genome stability, organization, and dynamics and in…”
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Conifers depend on established roots during drought: results from a coupled model of carbon allocation and hydraulics by Mackay, D. Scott, Savoy, Philip R., Grossiord, Charlotte, Tai, Xiaonan, Pleban, Jonathan R., Wang, Diane R., McDowell, Nathan G., Adams, Henry D., Sperry, John S.

“…• Trees may survive prolonged droughts by shifting water uptake to reliable water sources, but it is unknown if the dominant mechanism involves activating…”
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Ethylene-gibberellin signaling underlies adaptation of rice to periodic flooding by Kuroha, Takeshi, Nagai, Keisuke, Gamuyao, Rico, Wang, Diane R, Furuta, Tomoyuki, Nakamori, Masanari, Kitaoka, Takuya, Adachi, Keita, Minami, Anzu, Mori, Yoshinao, Mashiguchi, Kiyoshi, Seto, Yoshiya, Yamaguchi, Shinjiro, Kojima, Mikiko, Sakakibara, Hitoshi, Wu, Jianzhong, Ebana, Kaworu, Mitsuda, Nobutaka, Ohme-Takagi, Masaru, Yanagisawa, Shuichi, Yamasaki, Masanori, Yokoyama, Ryusuke, Nishitani, Kazuhiko, Mochizuki, Toshihiro, Tamiya, Gen, McCouch, Susan R, Ashikari, Motoyuki

“…Most plants do poorly when flooded. Certain rice varieties, known as deepwater rice, survive periodic flooding and consequent oxygen deficiency by activating…”
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Positive effects of public breeding on US rice yields under future climate scenarios by Wang, Diane R, Jamshidi, Sajad, Han, Rongkui, Edwards, Jeremy D, McClung, Anna M, McCouch, Susan R

“…In this study, we model and predict rice yields by integrating molecular marker variation, varietal productivity, and climate, focusing on the Southern U.S…”
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