Search Results - "WALTHER, FRANS J."

Efficacy, dose-response, and aerosol delivery of dry powder synthetic lung surfactant treatment in surfactant-deficient rabbits and premature lambs by Walther, Frans J, Waring, Alan J, Otieno, Monicah, DiBlasi, Robert M

“…Dry powder (DP) synthetic lung surfactant may be an effective means of noninvasive delivery of surfactant therapy to premature infants supported with nasal…”
Get full text

Emulation of the structure of the Saposin protein fold by a lung surfactant peptide construct of surfactant Protein B by Waring, Alan J, Whitelegge, Julian P, Sharma, Shantanu K, Gordon, Larry M, Walther, Frans J

“…The three-dimensional structure of the synthetic lung Surfactant Protein B Peptide Super Mini-B was determined using an integrative experimental approach,…”
Get full text

Aerosol, chemical and physical properties of dry powder synthetic lung surfactant for noninvasive treatment of neonatal respiratory distress syndrome by Walther, Frans J., Chan, Holly, Smith, Jacob R., Tauber, Mike, Waring, Alan J.

“…Inhalation of dry powder synthetic lung surfactant may assist spontaneous breathing by providing noninvasive surfactant therapy for premature infants supported…”
Get full text

Neonatal hematological parameters and the risk of moderate-severe bronchopulmonary dysplasia in extremely premature infants by Chen, Xueyu, Li, Huitao, Qiu, Xiaomei, Yang, Chuanzhong, Walther, Frans J

“…To evaluate the association between hematological parameters at birth and the risk of moderate-severe bronchopulmonary dysplasia (BPD) in a cohort of extremely…”
Get full text

Vascular and pulmonary effects of ibuprofen on neonatal lung development by Chen, Xueyu, Han, Dongshan, Wang, Xuan, Huang, Xuemei, Huang, Zilu, Liu, Yijun, Zhong, Junyan, Walther, Frans J, Yang, Chuanzhong, Wagenaar, Gerry T M

“…Ibuprofen is a nonsteroidal anti-inflammatory drug that is commonly used to stimulate closure of a patent ductus arteriosus (PDA) in very premature infants and…”
Get full text

Lung Surfactant Protein B Peptide Mimics Interact with the Human ACE2 Receptor by Waring, Alan J, Jung, Grace C-L, Sharma, Shantanu K, Walther, Frans J

“…Lung surfactant is a complex mixture of phospholipids and surfactant proteins that is produced in alveolar type 2 cells. It prevents lung collapse by reducing…”
Get full text

Structure and Function of Canine SP-C Mimic Proteins in Synthetic Surfactant Lipid Dispersions by Walther, Frans J, Waring, Alan J

“…Lung surfactant is a mixture of lipids and proteins and is essential for air breathing in mammals. The hydrophobic surfactant proteins B and C (SP-B and SP-C)…”
Get full text

Aerosol Delivery of Lung Surfactant and Nasal CPAP in the Treatment of Neonatal Respiratory Distress Syndrome by Walther, Frans J., Waring, Alan J.

“…After shifting away from invasive mechanical ventilation and intratracheal instillation of surfactant toward non-invasive ventilation with nasal CPAP and less…”
Get full text

Structural and functional stability of the sulfur-free surfactant protein B peptide mimic B-YL in synthetic surfactant lipids by Walther, Frans J, Sharma, Shantanu, Gordon, Larry M, Waring, Alan J

“…Optimal functionality of synthetic lung surfactant for treatment of respiratory distress syndrome in preterm infants largely depends on the quality and…”
Get full text

Neonatal ibuprofen exposure and bronchopulmonary dysplasia in extremely premature infants by Chen, Xueyu, Qiu, Xiaomei, Sun, Panpan, Lin, Yanqing, Huang, Zhifeng, Yang, Chuanzhong, Walther, Frans J.

“…Objective To evaluate the association of ibuprofen exposure with the risk of bronchopulmonary dysplasia (BPD) in extremely premature infants. Study design This…”
Get full text

Evaluating Manual Inflations and Breathing during Mask Ventilation in Preterm Infants at Birth by Schilleman, Kim, MD, PhD, van der Pot, Corinne J.M, Hooper, Stuart B., PhD, Lopriore, Enrico, MD, PhD, Walther, Frans J., MD, PhD, te Pas, Arjan B., MD, PhD

“…Objective To investigate inflations (initial sustained inflations and consecutive inflations) and breathing during mask ventilation in preterm infants at…”
Get full text

Long-term neurodevelopmental outcome after intrauterine transfusion for hemolytic disease of the fetus/newborn: the LOTUS study by Lindenburg, Irene T., MD, Smits-Wintjens, Vivianne E., MD, van Klink, Jeanine M., MSc, Verduin, Esther, MD, van Kamp, Inge L., MD, PhD, Walther, Frans J., MD, PhD, Schonewille, Henk, MD, PhD, Doxiadis, Ilias I., MD, PhD, Kanhai, Humphrey H., MD, PhD, van Lith, Jan M., MD, PhD, van Zwet, Erik W., MD, PhD, Oepkes, Dick, MD, PhD, Brand, Anneke, MD, PhD, Lopriore, Enrico, MD, PhD

“…Objective To determine the incidence and risk factors for neurodevelopmental impairment (NDI) in children with hemolytic disease of the fetus/newborn treated…”
Get full text

A Combination of the Aerosolized PPAR-γ Agonist Pioglitazone and a Synthetic Surfactant Protein B Peptide Mimic Prevents Hyperoxia-Induced Neonatal Lung Injury in Rats by Sakurai, Reiko, Lee, Cindy, Shen, Humphrey, Waring, Alan J, Walther, Frans J, Rehan, Virender K

“…Despite improvements in perinatal care, bronchopulmonary dysplasia (BPD) in extremely premature infants has not decreased. Postnatal surfactant therapy…”
Get more information

Measuring physiological changes during the transition to life after birth by van Vonderen, Jeroen J, Roest, Arno A W, Siew, Melissa L, Walther, Frans J, Hooper, Stuart B, te Pas, Arjan B

“…The transition to life after birth is characterized by major physiological changes in respiratory and hemodynamic function, which are predominantly initiated…”
Get more information

Mortality, neonatal morbidity and two year follow-up of extremely preterm infants born in The Netherlands in 2007 by de Waal, Cornelia G, Weisglas-Kuperus, Nynke, van Goudoever, Johannes B, Walther, Frans J

“…Extremely preterm infants are at high risk of neonatal mortality and adverse outcome. Survival rates are slowly improving, but increased survival may come at…”
Get full text

Evaluation of a Novel Dry Powder Surfactant Aerosol Delivery System for Use in Premature Infants Supported with Bubble CPAP by DiBlasi, Robert M, Crandall, Coral N, Engberg, Rebecca J, Bijlani, Kunal, Ledee, Dolena, Kajimoto, Masaki, Walther, Frans J

“…Aerosolized lung surfactant therapy during nasal continuous positive airway pressure (CPAP) support avoids intubation but is highly complex, with reported poor…”
Get full text

The pregnancy and long-term neurodevelopmental outcome of monochorionic diamniotic twin gestations: a multicenter prospective cohort study from the first trimester onward by Ortibus, Els, MD, Lopriore, Enrico, MD, PhD, Deprest, Jan, MD, PhD, Vandenbussche, Frank P., MD, PhD, Walther, Frans J., MD, PhD, Diemert, Anke, MD, Hecher, Kurt, MD, PhD, Lagae, Lieven, MD, PhD, De Cock, Paul, MD, PhD, Lewi, Paul J., PhD, Eng, Lewi, Liesbeth, MD, PhD

“…Objectives We sought to document the pregnancy and neurodevelopmental outcome in monochorionic diamniotic twin pregnancies and to identify risk factors for…”
Get full text

Sildenafil attenuates pulmonary inflammation and fibrin deposition, mortality and right ventricular hypertrophy in neonatal hyperoxic lung injury by de Visser, Yvonne P, Walther, Frans J, Laghmani, El Houari, Boersma, Hester, van der Laarse, Arnoud, Wagenaar, Gerry Tm

“…Phosphodiesterase-5 inhibition with sildenafil has been used to treat severe pulmonary hypertension and bronchopulmonary dysplasia (BPD), a chronic lung…”
Get full text

Mask versus Nasal Tube for Stabilization of Preterm Infants at Birth: Respiratory Function Measurements by van Vonderen, Jeroen J., PhD, Kamlin, C. Omar, MD, PhD, Dawson, Jennifer A., RN, PhD, Walther, Frans J., MD, PhD, Davis, Peter G., MD, te Pas, Arjan B., MD, PhD

“…Objective To compare the nasal tube with face mask as interfaces for stabilization of very preterm infants at birth by using physiological measurements of…”
Get full text

Thrombocytopenia in neonates and the risk of intraventricular hemorrhage: a retrospective cohort study by von Lindern, Jeannette S, van den Bruele, Tjitske, Lopriore, Enrico, Walther, Frans J

“…The overall prevalence of thrombocytopenia in neonates admitted to neonatal intensive care units ranges from 22 to 35%. There are only a few small studies that…”
Get full text