Search Results - "WALTERHOUSE, David O"
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Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis
Published in Development (Cambridge) (01-06-2017)“…Cleft lip is one of the most common human birth defects, yet our understanding of the mechanisms that regulate lip morphogenesis is limited. Here, we show in…”
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Results of the Intergroup Rhabdomyosarcoma Study Group D9602 Protocol, Using Vincristine and Dactinomycin With or Without Cyclophosphamide and Radiation Therapy, for Newly Diagnosed Patients With Low-Risk Embryonal Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group
Published in Journal of clinical oncology (01-04-2011)“…Patients with localized, grossly resected, or gross residual (orbital only) embryonal rhabdomyosarcoma (ERMS) had 5-year failure-free survival (FFS) rates of…”
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Histologic and Clinical Characteristics Can Guide Staging Evaluations for Children and Adolescents With Rhabdomyosarcoma: A Report From the Children's Oncology Group Soft Tissue Sarcoma Committee
Published in Journal of clinical oncology (10-09-2013)“…To simplify the recommended staging evaluation by correlating tumor and clinical features with patterns of distant metastasis in newly diagnosed patients with…”
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Randomized Phase II Window Trial of Two Schedules of Irinotecan With Vincristine in Patients With First Relapse or Progression of Rhabdomyosarcoma: A Report From the Children's Oncology Group
Published in Journal of clinical oncology (20-10-2010)“…To compare response rates for two schedules of irinotecan with vincristine in patients with rhabdomyosarcoma at first relapse or disease progression. Patients…”
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The significance of margins in pediatric Non‐Rhabdomyosarcoma soft tissue sarcomas: Consensus on surgical margin definition harmonization from the INternational Soft Tissue SaRcoma ConsorTium (INSTRuCT)
Published in Cancer medicine (Malden, MA) (01-05-2023)“…Background Margin status following surgery in children, adolescents, and young adults with soft tissue sarcomas is controversial and has been defined…”
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Severe labile hypertension in a patient with catecholamine-secreting neuroblastoma: a case report
Published in Pediatric nephrology (Berlin, West) (01-07-2024)“…Neuroblastoma is a common pediatric tumor arising from the post-ganglionic sympathetic nervous system and is associated with hypertension in 25% of cases. We…”
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Quantification of Vincristine and its Major Metabolite in Human Plasma by High-Performance Liquid Chromatography/Tandem Mass Spectrometry
Published in Therapeutic drug monitoring (01-06-2008)“…An analytical method using electrospray ionization and high-performance liquid chromatography/tandem mass spectrometry (LC/ESI-MS/MS) was developed to quantify…”
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The treatment approach to pediatric non-rhabdomyosarcoma soft tissue sarcomas: a critical review from the INternational Soft Tissue SaRcoma ConsorTium
Published in European journal of cancer (1990) (01-07-2022)“…The current article focuses on non-rhabdomyosarcoma soft tissue sarcoma (NRSTS), the heterogeneous group of mesenchymal tumours different from rhabdomyosarcoma…”
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Efficacy of Topotecan and Cyclophosphamide Given in a Phase II Window Trial in Children With Newly Diagnosed Metastatic Rhabdomyosarcoma: A Children’s Oncology Group Study
Published in Journal of clinical oncology (15-04-2004)“…To determine the antitumor activity and toxicity of topotecan given immediately after cyclophosphamide as window therapy, then in combination with conventional…”
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Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group
Published in Journal of clinical oncology (01-11-2014)“…Intergroup Rhabdomyosarcoma Study Group (IRSG) studies III and IV showed improved failure-free survival (FFS) rates with vincristine, dactinomycin, and…”
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Reduction of cyclophosphamide dose for patients with subset 2 low‐risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group
Published in Cancer (15-06-2017)“…BACKGROUND Failure‐free survival (FFS) and overall survival (OS) rates were found to improve on Intergroup Rhabdomyosarcoma Study (IRS) IV (IRS‐IV) compared…”
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Survival of Patients With Non‐Rhabdomyosarcoma Soft Tissue Sarcomas of the Head and Neck
Published in The Laryngoscope (01-02-2021)“…Objective To evaluate factors associated with overall survival (OS) of patients with non‐rhabdomyosarcoma soft tissue sarcomas of the head and neck. Study…”
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Patients with completely resected nongenitourinary low‐risk embryonal rhabdomyosarcoma are candidates for reduced duration low‐intensity chemotherapy
Published in Cancer (01-12-2022)“…Background The survival of patients with localized embryonal rhabdomyosarcoma (RMS) completely resected at diagnosis is greater than 90%. Most patients have…”
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Suboptimal outcome for patients with biliary rhabdomyosarcoma treated on low‐risk clinical trials: A report from the Children's Oncology Group
Published in Pediatric blood & cancer (01-04-2021)“…Background Biliary rhabdomyosarcoma (RMS) is the most common biliary tumor in children. The biliary tract is classified as a favorable primary site. Therefore,…”
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Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee
Published in International journal of cancer (01-12-2020)“…Paratesticular rhabdomyosarcoma (PT‐RMS) carries a favorable prognosis, but questions persist regarding optimal management. Our goal was to determine the…”
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Cardiac-Sparing Whole Lung IMRT in Patients With Pediatric Tumors and Lung Metastasis: Final Report of a Prospective Multicenter Clinical Trial
Published in International journal of radiation oncology, biology, physics (01-01-2019)“…A prospective clinical trial was conducted for patients undergoing cardiac sparing (CS) whole lung irradiation (WLI) using intensity modulated radiation…”
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Risk‐based treatment for patients with first relapse or progression of rhabdomyosarcoma: A report from the Children's Oncology Group
Published in Cancer (01-08-2019)“…Background The purpose of this study was to evaluate risk and response–based multi‐agent therapy for patients with rhabdomyosarcoma (RMS) at first relapse…”
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Emerging Roles for Hedgehog-Patched-Gli Signal Transduction in Reproduction
Published in Biology of reproduction (01-07-2003)“…Hedgehog (Hh) proteins are expressed during vertebrate development in some tissues with inductive properties and at epithelial-mesenchymal boundaries in…”
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Clinical group and modified TNM stage for rhabdomyosarcoma: A review from the Children's Oncology Group
Published in Pediatric blood & cancer (01-06-2022)“…The Children's Oncology Group (COG) uses Clinical Group (CG) and modified Tumor Node Metastasis (TNM) stage to classify rhabdomyosarcoma (RMS). CG is based on…”
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Serologic response and clinical efficacy of influenza vaccination in children and young adults on chemotherapy for cancer
Published in Pediatric blood & cancer (01-11-2016)“…Background Influenza is a health risk to children receiving chemotherapy for cancer. An absolute lymphocyte count (ALC) >1,000 cells/mm3 has been associated…”
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