Search Results - "WALTER, Mary"
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Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake
Published in Cell metabolism (02-07-2019)“…We investigated whether ultra-processed foods affect energy intake in 20 weight-stable adults, aged (mean ± SE) 31.2 ± 1.6 years and BMI = 27 ± 1.5 kg/m2…”
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Persistent metabolic adaptation 6 years after “The Biggest Loser” competition
Published in Obesity (Silver Spring, Md.) (01-08-2016)“…Objective To measure long‐term changes in resting metabolic rate (RMR) and body composition in participants of “The Biggest Loser” competition. Methods Body…”
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Reduced Insulin Clearance and Insulin-Degrading Enzyme Activity Contribute to Hyperinsulinemia in African Americans
Published in The journal of clinical endocrinology and metabolism (01-04-2020)“…Abstract Background African Americans (AAs) are at a higher risk for developing type 2 diabetes compared with non-Hispanic whites (NHWs). The causal role of…”
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4
Impaired Metabolic Flexibility to High-Fat Overfeeding Predicts Future Weight Gain in Healthy Adults
Published in Diabetes (New York, N.Y.) (01-02-2020)“…The ability to switch fuels for oxidation in response to changes in macronutrient composition of diet (metabolic flexibility) may be informative of…”
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Effect of a plant-based, low-fat diet versus an animal-based, ketogenic diet on ad libitum energy intake
Published in Nature medicine (01-02-2021)“…The carbohydrate–insulin model of obesity posits that high-carbohydrate diets lead to excess insulin secretion, thereby promoting fat accumulation and…”
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Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity
Published in The Journal of clinical investigation (01-05-2020)“…BACKGROUNDMirabegron is a β3-adrenergic receptor (β3-AR) agonist approved only for the treatment of overactive bladder. Encouraging preclinical results suggest…”
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Itaconate and leptin affecting PPARγ in M2 macrophages: A potential link to early-onset colorectal cancer
Published in Surgery (01-03-2022)“…Along with the rising incidence of obesity, there has been an increase in patients diagnosed with early-onset colorectal cancer (<50 years old). In colorectal…”
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Insulin Signaling Through the Insulin Receptor Increases Linear Growth Through Effects on Bone and the GH–IGF-1 Axis
Published in The journal of clinical endocrinology and metabolism (21-12-2023)“…Abstract Context Childhood overnutrition is associated with increased growth and bone mineral density (BMD) vs the opposite for undernutrition. The role of…”
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Ingestion of Diet Soda Before a Glucose Load Augments Glucagon-Like Peptide-1 Secretion
Published in Diabetes care (01-12-2009)“…Ingestion of Diet Soda Before a Glucose Load Augments Glucagon-Like Peptide-1 Secretion Rebecca J. Brown , MD , Mary Walter , PHD and Kristina I. Rother , MD,…”
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Urinary Dopamine Excretion Rate Decreases during Acute Dietary Protein Deprivation and Is Associated with Increased Plasma Pancreatic Polypeptide Concentration
Published in Nutrients (08-04-2021)“…Dopamine, a key neurotransmitter in the autonomic nervous system participating in the homeostatic balance between sympathetic and parasympathetic divisions, is…”
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Erythropoietin reduces fat mass in female mice lacking estrogen receptor alpha
Published in Molecular metabolism (Germany) (01-03-2021)“…Erythropoietin (EPO), the cytokine required for erythropoiesis, contributes to metabolic regulation of fat mass and glycemic control. EPO treatment in mice on…”
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Canagliflozin triggers the FGF23/1,25-dihydroxyvitamin D/PTH axis in healthy volunteers in a randomized crossover study
Published in JCI insight (19-04-2018)“…Sodium glucose cotransporter-2 (SGLT2) inhibitors are the most recently approved class of drugs for type 2 diabetes and provide both glycemic efficacy and…”
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13
The effects of an exercise program on inflammation in adults who differ according to obstructive sleep apnea severity
Published in Sleep and biological rhythms (01-07-2024)“…Exercise improves chronic inflammation and is recommended as a first-line medical or behavioral treatment for OSA with obesity. We examined whether the effects…”
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Prior Vaccination Exceeds Prior Infection in Eliciting Innate and Humoral Immune Responses in Omicron Infected Outpatients
Published in Frontiers in immunology (15-06-2022)“…Antibody response following Omicron infection is reported to be less robust than that to other variants. Here we investigated how prior vaccination and/or…”
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A Blood-based Polyamine Signature Associated With MEN1 Duodenopancreatic Neuroendocrine Tumor Progression
Published in The journal of clinical endocrinology and metabolism (01-12-2021)“…Duodenopancreatic neuroendocrine tumors (dpNETs) frequently occur in patients with multiple endocrine neoplasia type 1 (MEN1), and metastatic dpNET is the…”
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Blood-based Proteomic Signatures Associated With MEN1-related Duodenopancreatic Neuroendocrine Tumor Progression
Published in The journal of clinical endocrinology and metabolism (01-12-2023)“…Abstract Purpose Patients with multiple endocrine neoplasia type 1 (MEN1) are predisposed to develop duodenopancreatic neuroendocrine tumors (dpNETs), and…”
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Two distinct classes of thymic tumors in patients with MEN1 show LOH at the MEN1 locus
Published in Endocrine-related cancer (01-11-2021)“…Patients with the multiple endocrine neoplasia type 1 (MEN1) syndrome carry germline heterozygous loss-of-function mutations in the MEN1 gene which predisposes…”
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Effect of Enhanced Glycemic Control with Saxagliptin on Endothelial Nitric Oxide Release and CD40 Levels in Obese Rats
Published in Journal of Atherosclerosis and Thrombosis (01-01-2011)“…Aim: Endothelial cell (EC) dysfunction contributes to insulin resistance in diabetes and is characterized by reduced nitric oxide (NO) release, increased…”
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Limited cross-variant immune response from SARS-CoV-2 Omicron BA.2 in naïve but not previously infected outpatients
Published in iScience (18-11-2022)“…Omicron is currently the dominant SARS-CoV-2 variant and several sublineages have emerged. Questions remain about the impact of previous SARS-CoV-2 exposure on…”
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Metabolic Synergy between Human Symbionts Bacteroides and Methanobrevibacter
Published in Microbiology spectrum (29-06-2022)“…Trophic interactions between microbes are postulated to determine whether a host microbiome is healthy or causes predisposition to disease. Two abundant taxa,…”
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