Search Results - "WALTER, Martin A"

2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis by Ross, Douglas S, Burch, Henry B, Cooper, David S, Greenlee, M Carol, Laurberg, Peter, Maia, Ana Luiza, Rivkees, Scott A, Samuels, Mary, Sosa, Julie Ann, Stan, Marius N, Walter, Martin A

“…Thyrotoxicosis has multiple etiologies, manifestations, and potential therapies. Appropriate treatment requires an accurate diagnosis and is influenced by…”
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Response, Survival, and Long-Term Toxicity After Therapy With the Radiolabeled Somatostatin Analogue [90Y-DOTA]-TOC in Metastasized Neuroendocrine Cancers by IMHOF, Anna, BRUNNER, Philippe, MARINCEK, Nicolas, BRIEL, Matthias, SCHINDLER, Christian, RASCH, Helmut, MÄCKE, Helmut R, ROCHLITZ, Christoph, MÜLLER-BRAND, Jan, WALTER, Martin A

“…To investigate response, survival, and safety profile of the somatostatin-based radiopeptide (90)yttrium-labeled tetraazacyclododecane-tetraacetic acid…”
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Peptide receptor radionuclide therapy in gastroenteropancreatic NEN G3: a multicenter cohort study by Carlsen, Esben Andreas, Fazio, Nicola, Granberg, Dan, Grozinsky-Glasberg, Simona, Ahmadzadehfar, Hojjat, Grana, Chiara Maria, Zandee, Wouter T, Cwikla, Jaroslaw, Walter, Martin A, Oturai, Peter Sandor, Rinke, Anja, Weaver, Andrew, Frilling, Andrea, Gritti, Sara, Arveschoug, Anne Kirstine, Meirovitz, Amichay, Knigge, Ulrich, Sorbye, Halfdan

“…Peptide receptor radionuclide therapy (PRRT) is an established treatment of metastatic neuroendocrine tumors grade 1–2 (G1–G2). However, its possible benefit…”
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Somatostatin Receptor-Targeted Radiopeptide Therapy in Treatment-Refractory Meningioma: Individual Patient Data Meta-analysis by Mirian, Christian, Duun-Henriksen, Anne Katrine, Maier, Andrea, Pedersen, Maria Møller, Jensen, Lasse Rehné, Bashir, Asma, Graillon, Thomas, Hrachova, Maya, Bota, Daniela, van Essen, Martjin, Spanjol, Petar, Kreis, Christian, Law, Ian, Broholm, Helle, Poulsgaard, Lars, Fugleholm, Kåre, Ziebell, Morten, Munch, Tina, Walter, Martin A, Mathiesen, Tiit

“…Somatostatin receptor (SSTR)-targeted peptide receptor radionuclide therapy (PRRT) represents a promising approach for treatment-refractory meningiomas. We…”
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The Imageable Genome by Jané, Pablo, Xu, Xiaoying, Taelman, Vincent, Jané, Eduardo, Gariani, Karim, Dumont, Rebecca A., Garama, Yonathan, Kim, Francisco, del Val Gomez, María, Walter, Martin A.

“…Understanding human disease on a molecular level, and translating this understanding into targeted diagnostics and therapies are central tenets of molecular…”
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Cohort Study of Somatostatin-Based Radiopeptide Therapy With [90Y-DOTA]-TOC Versus [90Y-DOTA]-TOC Plus [177Lu-DOTA]-TOC in Neuroendocrine Cancers by VILLARD, Linda, ROMER, Anna, BRIEL, Matthias, WALTER, Martin A, MARINCEK, Nicolas, BRUNNER, Philippe, KOLLER, Michael T, SCHINDLER, Christian, NG, Quinn KT, MÄCKE, Helmut R, MÜLLER-BRAND, Jan, ROCHLITZ, Christoph

“…Radiopeptide therapy is commonly performed with a single radioisotope. We aimed to compare the effectiveness of somatostatin-based radiopeptide therapy with a…”
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The value of [18F]FDG-PET in the diagnosis of large-vessel vasculitis and the assessment of activity and extent of disease by Walter, Martin A, Melzer, Ralph A, Schindler, Christian, Müller-Brand, Jan, Tyndall, Alan, Nitzsche, Egbert U

“…This study was performed to investigate the value of( 18)F-fluorodeoxyglucose positron emission tomography ([(18)F]FDG-PET) in the diagnosis of large-vessel…”
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Response to [90Yttrium-DOTA]-TOC Treatment is Associated with Long-term Survival Benefit in Metastasized Medullary Thyroid Cancer: A Phase II Clinical Trial by ITEN, Fabienne, MÜLLER, Beat, SCHINDLER, Christian, ROCHLITZ, Christoph, OERTLI, Daniel, MÄCKE, Helmut R, MÄLLER-BRAND, Jan, WALTER, Martin A

“…Purpose: We aimed to explore the efficacy of 90 Yttrium–1,4,7,10-tetra-azacyclododecane N,N′,N″,N -‴-tetraacetic acid ( 90 Y-DOTA)–Tyr 3 -octreotide (TOC)…”
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Risk profiles and penetrance estimations in multiple endocrine neoplasia type 2A caused by germline RET mutations located in exon 10 by Frank-Raue, Karin, Rybicki, Lisa A., Erlic, Zoran, Schweizer, Heiko, Winter, Aurelia, Milos, Ioana, Toledo, Sergio P.A., Toledo, Rodrigo A., Tavares, Marcos R., Alevizaki, Maria, Mian, Caterina, Siggelkow, Heide, Hüfner, Michael, Wohllk, Nelson, Opocher, Giuseppe, Dvořáková, Šárka, Bendlova, Bela, Czetwertynska, Małgorzata, Skasko, Elżbieta, Barontini, Marta, Sanso, Gabriela, Vorländer, Christian, Maia, Ana Luiza, Patocs, Attila, Links, Thera P., de Groot, Jan Willem, Kerstens, Michiel N., Valk, Gerlof D., Miehle, Konstanze, Musholt, Thomas J., Biarnes, Josefina, Damjanovic, Svetozar, Muresan, Mihaela, Wüster, Christian, Fassnacht, Martin, Peczkowska, Mariola, Fauth, Christine, Golcher, Henriette, Walter, Martin A., Pichl, Josef, Raue, Friedhelm, Eng, Charis, Neumann, Hartmut P.H.

“…Multiple endocrine neoplasia type 2 is characterized by germline mutations in RET. For exon 10, comprehensive molecular and corresponding phenotypic data are…”
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On transcending the impasse of respiratory motion correction applications in routine clinical imaging - a consideration of a fully automated data driven motion control framework by Kesner, Adam L, Schleyer, Paul J, Büther, Florian, Walter, Martin A, Schäfers, Klaus P, Koo, Phillip J

“…Positron emission tomography (PET) is increasingly used for the detection, characterization, and follow-up of tumors located in the thorax. However, patient…”
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[18 F]Fluorodeoxyglucose PET in Large Vessel Vasculitis by Walter, Martin A., MD

“…[18 F]fluorodeoxyglucose (FDG) PET is a noninvasive metabolic imaging modality based on the regional distribution of [18F]FDG that is highly effective in…”
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Preclinical Evaluation of New and Highly Potent Analogues of Octreotide for Predictive Imaging and Targeted Radiotherapy by GINJ, Mihaela, JIANHUA CHEN, WALTER, Martin A, ELTSCHINGER, Veronique, REUBI, Jean Claude, MAECKE, Helmut R

“…Purpose: Molecular imaging and targeted radiotherapy are emerging fields in nuclear oncology. Five human somatostatin receptors (hsstr1-hsstr5) are known to be…”
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Noninvasive prediction of tumor responses to gemcitabine using positron emission tomography by Laing, Rachel E, Walter, Martin A, Campbell, Dean O, Herschman, Harvey R, Satyamurthy, Nagichettiar, Phelps, Michael E, Czernin, Johannes, Witte, Owen N, Radu, Caius G

“…Gemcitabine (2',2'-difluorodeoxycytidine, dFdC) and cytosine arabinoside (cytarabine, ara-C) represent a class of nucleoside analogs used in cancer…”
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Learning from failure--rationale and design for a study about discontinuation of randomized trials (DISCO study) by Kasenda, Benjamin, von Elm, Erik B, You, John, Blümle, Anette, Tomonaga, Yuki, Saccilotto, Ramon, Amstutz, Alain, Bengough, Theresa, Meerpohl, Jörg, Stegert, Mihaela, Tikkinen, Kari A O, Neumann, Ignacio, Carrasco-Labra, Alonso, Faulhaber, Markus, Mulla, Sohail, Mertz, Dominik, Akl, Elie A, Bassler, Dirk, Busse, Jason W, Ferreira-González, Ignacio, Lamontagne, Francois, Nordmann, Alain, Rosenthal, Rachel, Schandelmaier, Stefan, Sun, Xin, Vandvik, Per O, Johnston, Bradley C, Walter, Martin A, Burnand, Bernard, Schwenkglenks, Matthias, Bucher, Heiner C, Guyatt, Gordon H, Briel, Matthias

“…Randomized controlled trials (RCTs) may be discontinued because of apparent harm, benefit, or futility. Other RCTs are discontinued early because of…”
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Somatostatin-based radiotherapy with [90Y-DOTA]-TOC in neuroendocrine tumors: long-term outcome of a phase I dose escalation study by Marincek, Nicolas, Jörg, Ann-Catherine, Brunner, Philippe, Schindler, Christian, Koller, Michael T, Rochlitz, Christoph, Müller-Brand, Jan, Maecke, Helmut R, Briel, Matthias, Walter, Martin A

“…We describe the long-term outcome after clinical introduction and dose escalation of somatostatin receptor targeted therapy with [90Y-DOTA]-TOC in patients…”
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1,2,3-Triazoles as Amide Bond Mimics: Triazole Scan Yields Protease-Resistant Peptidomimetics for Tumor Targeting by Valverde, Ibai E., Bauman, Andreas, Kluba, Christiane A., Vomstein, Sandra, Walter, Martin A., Mindt, Thomas L.

“…The triazole makes the difference: Replacement of amide bonds in the backbone of peptides by 1,4‐disubstituted 1,2,3‐triazole isosteres affords peptidomimetics…”
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FDG-PET/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC by Slart, Riemer H. J. A.

“…Large vessel vasculitis (LVV) is defined as a disease mainly affecting the large arteries, with two major variants, Takayasu arteritis (TA) and giant cell…”
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Metabolic imaging allows early prediction of response to vandetanib by Walter, Martin A, Benz, Matthias R, Hildebrandt, Isabel J, Laing, Rachel E, Hartung, Verena, Damoiseaux, Robert D, Bockisch, Andreas, Phelps, Michael E, Czernin, Johannes, Weber, Wolfgang A

“…The RET (rearranged-during-transfection protein) protooncogene triggers multiple intracellular signaling cascades regulating cell cycle progression and…”
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Prevalence, Characteristics, and Publication of Discontinued Randomized Trials by Kasenda, Benjamin, von Elm, Erik, You, John, Blümle, Anette, Tomonaga, Yuki, Saccilotto, Ramon, Amstutz, Alain, Bengough, Theresa, Meerpohl, Joerg J, Stegert, Mihaela, Tikkinen, Kari A. O, Neumann, Ignacio, Carrasco-Labra, Alonso, Faulhaber, Markus, Mulla, Sohail M, Mertz, Dominik, Akl, Elie A, Bassler, Dirk, Busse, Jason W, Ferreira-González, Ignacio, Lamontagne, Francois, Nordmann, Alain, Gloy, Viktoria, Raatz, Heike, Moja, Lorenzo, Rosenthal, Rachel, Ebrahim, Shanil, Schandelmaier, Stefan, Xin, Sun, Vandvik, Per O, Johnston, Bradley C, Walter, Martin A, Burnand, Bernard, Schwenkglenks, Matthias, Hemkens, Lars G, Bucher, Heiner C, Guyatt, Gordon H, Briel, Matthias

“…IMPORTANCE The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. The epidemiology of…”
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Upregulation of Key Molecules for Targeted Imaging and Therapy by Taelman, Vincent F, Radojewski, Piotr, Marincek, Nicolas, Ben-Shlomo, Anat, Grotzky, Andrea, Olariu, Cristina I, Perren, Aurel, Stettler, Christoph, Krause, Thomas, Meier, Lorenz P, Cescato, Renzo, Walter, Martin A

“…Targeted diagnosis and therapy enable precise tumor detection and treatment. Successful examples for precise tumor targeting are diagnostic and therapeutic…”
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