Search Results - "WALSH, F. S"

Edg8/S1P5: An Oligodendroglial Receptor with Dual Function on Process Retraction and Cell Survival by Jaillard, C, Harrison, S, Stankoff, B, Aigrot, M. S, Calver, A. R, Duddy, G, Walsh, F. S, Pangalos, M. N, Arimura, N, Kaibuchi, K, Zalc, B, Lubetzki, C

“…Endothelial differentiation gene (Edg) proteins are G-protein-coupled receptors activated by lysophospholipid mediators: sphingosine-1-phosphate (S1P) or…”
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Automated computer-based CT stratification as a predictor of outcome in hypersensitivity pneumonitis by Jacob, Joseph, Bartholmai, B. J., Rajagopalan, S., Karwoski, R., Mak, S. M., Mok, W., Della Casa, G., Sugino, K., Walsh, S. L. F., Wells, A. U., Hansell, D. M.

“…Background Hypersensitivity pneumonitis (HP) has a variable clinical course. Modelling of quantitative CALIPER-derived CT data can identify distinct disease…”
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Myostatin as a therapeutic target for musculoskeletal disease by Bradley, L, Yaworsky, P. J, Walsh, F. S

“…Adult skeletal muscle is a dynamic tissue undergoing a continuous round of stem cell activation, proliferation and differentiation. A number of myogenic cell…”
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The p53 response to ionising radiation in adult and developing murine tissues by MacCallum, D E, Hupp, T R, Midgley, C A, Stuart, D, Campbell, S J, Harper, A, Walsh, F S, Wright, E G, Balmain, A, Lane, D P, Hall, P A

“…The induction of the p53 response to ionising radiation has been studied during murine development and in the adult animal. The response has been assessed by…”
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ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site by Hussain, I., Powell, D.J., Howlett, D.R., Chapman, G.A., Gilmour, L., Murdock, P.R., Tew, D.G., Meek, T.D., Chapman, C., Schneider, K., Ratcliffe, S.J., Tattersall, D., Testa, T.T., Southan, C., Ryan, D.M., Simmons, D.L., Walsh, F.S., Dingwall, C., Christie, G.

“…Sequential proteolytic processing of the Amyloid Precursor Protein (APP) by β- and γ-secretases generates the 4-kDa amyloid (Aβ) peptide, a key component of…”
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Induction of experimental autoimmune neuritis with peripheral myelin protein-22 by GABRIEL, C. M, HUGHES, R. A. C, MOORE, S. E, SMITH, K. J, WALSH, F. S

“…Two myelin proteins, P2 basic protein and P0 glycoprotein, can induce experimental autoimmune neuritis (EAN), a model of human inflammatory neuropathy. We…”
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Tyrosine Kinase Inhibitors Can Differentially Inhibit Integrin-Dependent and CAM-Stimulated Neurite Outgrowth by Williams, Emma J., Walsh, Frank S., Doherty, Patrick

“…We have used monolayers of parental 3T3 cells and 3T3 cells expressing one of three transfected cell adhesion molecules (CAMs) (NCAM, N-cadherin, and L1) as a…”
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Inhibitor of neurite outgrowth in humans by PRINJHA, R, MOORE, S. E, VINSON, M, BLAKE, S, MORROW, R, CHRISTIE, G, MICHALOVICH, D, SIMMONS, D. L, WALSH, F. S

“…Axons are generally believed to be incapable of regeneration in the adult central nervous system. Inhibition results from physical barriers imposed by glial…”
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Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs by Acsadi, Gyula, Dickson, George, Love, Donald R, Jani, Agnes, Walsh, Frank S, Gurusinghe, Asitha, Wolff, Jon A, Davies, Kay E

“…Duchenne's muscular dystrophy (DMD), which affects one in 3,500 males, causes progressive myopathy of skeletal and cardiac muscles and premature death. One…”
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Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy by Wells, D J, Wells, K E, Asante, E A, Turner, G, Sunada, Y, Campbell, K P, Walsh, F S, Dickson, G

“…Duchenne muscular dystrophy (DMD) is a lethal X-linked recessive disorder with a high spontaneous mutation rate and no effective treatment, hence development…”
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Association between glycoconjugate antibodies and Campylobacter infection in patients with Guillain-Barré syndrome by Walsh, F S, Cronin, M, Koblar, S, Doherty, P, Winer, J, Leon, A, Hughes, R A

“…In a retrospective study, we have analysed sera from a well-characterised Guillain-Barré syndrome (GBS) patient group for antibodies that react with…”
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Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF by WILLIAMS, E. J, FURNESS, J, WALSH, F. S, DOHERTY, P

“…Cerebellar neurons, cultured on monolayers of 3T3 fibroblasts or on a polylysine/laminin-coated substratum, responded to recombinant basic FGF by extending…”
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The production of arachidonic acid can account for calcium channel activation in the second messenger pathway underlying neurite outgrowth stimulated by NCAM, N-cadherin, and L1 by Williams, E J, Walsh, F S, Doherty, P

“…We have used monolayers of control 3T3 fibroblasts and 3T3 fibroblasts expressing transfected cell adhesion molecules (CAMs)--NCAM, N-cadherin, and L1--as a…”
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Differential Effects of Over-Expressed Neural Cell Adhesion Molecule Isoforms on Myoblast Fusion by Peck, David, Walsh, Frank S.

“…We have used a transfection based approach to analyze the role of neural cell adhesion molecule (NCAM) in myogenesis at the stage of myoblast fusion to form…”
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Epithelial (E-) and placental (P-) cadherin cell adhesion molecule expression in breast carcinoma by Rasbridge, S A, Gillett, C E, Sampson, S A, Walsh, F S, Millis, R R

“…Two members of the cadherin family of intercellular adhesion molecules are found in normal breast tissue: E-(epithelial) cadherin is present in both luminal…”
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Differential Display of Genes Expressed at the Midbrain – Hindbrain Junction Identifies sprouty2: An FGF8-Inducible Member of a Family of Intracellular FGF Antagonists by Chambers, D., Medhurst, A.D., Walsh, F.S., Price, J., Mason, I.

“…Specification and polarization of the midbrain and anterior hindbrain involve planar signals originating from the isthmus. Current evidence suggests that FGF8,…”
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Direct Activation of Second Messenger Pathways Mimics Cell Adhesion Molecule-Dependent Neurite Outgrowth by Saffell, Jane L., Walsh, Frank S., Doherty, Patrick

“…We present evidence that direct activation of neuronal second messenger pathways in PC12 cells by opening voltage-dependent calcium channels mimics cell…”
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Identification of two new Pmp22 mouse mutants using large-scale mutagenesis and a novel rapid mapping strategy by ISAACS, A. M, DAVIES, K. E, FISHER, E. M. C, BOUZYK, M. M, POTTER, A, MASIH, M, WALSH, F. S, SIMS, M. A, DONCASTER, K. E, PARSONS, C. A, MARTIN, J, BROWN, S. D. M, HUNTER, A. J, RASTAN, S, SPURR, N. K, GRAY, L. C, NOLAN, P. M, VIZOR, L, PETERS, J, GALE, D. G, KELSELL, D. P, LATHAM, I. D, CHASE, J. M

“…Mouse mutants have a key role in discerning mammalian gene function and modelling human disease; however, at present mutants exist for only 1-2% of all mouse…”
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The FGF Receptor Uses the Endocannabinoid Signaling System to Couple to an Axonal Growth Response by Williams, Emma-Jane, Walsh, Frank S., Doherty, Patrick

“…A key role for DAG lipase activity in the control of axonal growth and guidance in vitro and in vivo has been established. For example, DAG lipase activity is…”
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The cell adhesion molecule M-cadherin is specifically expressed in developing and regenerating, but not denervated skeletal muscle by MOORE, R, WALSH, F. S

“…The spatiotemporal distribution of M-cadherin mRNA has been determined by in situ hybridization in the mouse embryo and in adult skeletal muscle following…”
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