Search Results - "WALLS, Andrew F"

NADPH oxidase-independent formation of extracellular DNA traps by basophils by Morshed, Mahbubul, Hlushchuk, Ruslan, Simon, Dagmar, Walls, Andrew F, Obata-Ninomiya, Kazushige, Karasuyama, Hajime, Djonov, Valentin, Eggel, Alexander, Kaufmann, Thomas, Simon, Hans-Uwe, Yousefi, Shida

“…Basophils are primarily associated with a proinflammatory and immunoregulatory role in allergic diseases and parasitic infections. Recent studies have shown…”
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Mast cell chymase impairs bronchial epithelium integrity by degrading cell junction molecules of epithelial cells by Zhou, Xiaoying, Wei, Tao, Cox, Christopher W., Jiang, Yuan, Roche, William R., Walls, Andrew F.

“…Background An increased degree of mast cell (MC) degranulation and damage to the epithelial lining are prominent features of bronchial asthma. In asthmatic…”
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Innate and adaptive T cells in asthmatic patients: Relationship to severity and disease mechanisms by Hinks, Timothy S.C., MD, Zhou, Xiaoying, PhD, Staples, Karl J., PhD, Dimitrov, Borislav D., MD, Manta, Alexander, PhD, Petrossian, Tanya, PhD, Lum, Pek Y., PhD, Smith, Caroline G., RN, Ward, Jon A., BSc, Howarth, Peter H., MD, Walls, Andrew F., PhD, Gadola, Stephan D., MD, Djukanović, Ratko, MD

“…Background Asthma is a chronic inflammatory disease involving diverse cells and mediators whose interconnectivity and relationships to asthma severity are…”
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Eosinophils, basophils and type 2 immune microenvironments in COPD-affected lung tissue by Jogdand, Prajakta, Siddhuraj, Premkumar, Mori, Michiko, Sanden, Caroline, Jönsson, Jimmie, Walls, Andrew F, Kearley, Jennifer, Humbles, Alison A, Kolbeck, Roland, Bjermer, Leif, Newbold, Paul, Erjefält, Jonas S

“…Although elevated blood or sputum eosinophils are present in many patients with COPD, uncertainties remain regarding the anatomical distribution pattern of…”
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Editorial: Th2-associated immunity in the pathogenesis of systemic lupus erythematosus and rheumatoid arthritis by Pan, Quanren, Walls, Andrew F., Pan, Qingjun

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Decreased peripheral basophil counts in urticaria and mouse model of oxazolone-induced hypersensitivity, the latter suggesting basopenia reflecting migration to skin by Kishimoto, Izumi, Ma, Ni, Takimoto-Ito, Riko, Nakashima, Chisa, Otsuka, Atsushi, Walls, Andrew F., Tanizaki, Hideaki, Kambe, Naotomo

“…A decrease in the number of basophils in the peripheral blood, or basopenia, has been noted, reflecting the activity of chronic spontaneous urticaria (CSU)…”
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Effect of honey and its major royal jelly protein 1 on cytokine and MMP-9 mRNA transcripts in human keratinocytes by Majtan, Juraj, Kumar, Pawan, Majtan, Tomas, Walls, Andrew F., Klaudiny, Jaroslav

“…Please cite this paper as: Effect of honey and its major royal jelly protein 1 on cytokine and MMP‐9 mRNA transcripts in human keratinocytes. Experimental…”
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Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases by Metcalfe, Dean D., Pawankar, Ruby, Ackerman, Steven J., Akin, Cem, Clayton, Frederic, Falcone, Franco H., Gleich, Gerald J., Irani, Anne-Marie, Johansson, Mats W., Klion, Amy D., Leiferman, Kristin M., Levi-Schaffer, Francesca, Nilsson, Gunnar, Okayama, Yoshimichi, Prussin, Calman, Schroeder, John T., Schwartz, Lawrence B., Simon, Hans-Uwe, Walls, Andrew F., Triggiani, Massimo

“…Biomarkers of disease activity have come into wide use in the study of mechanisms of human disease and in clinical medicine to both diagnose and predict…”
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Alveolar T-helper type-2 immunity in atopic asthma is associated with poor clinical control by Bergqvist, Anders, Andersson, Cecilia K, Mori, Michiko, Walls, Andrew F, Bjermer, Leif, Erjefält, Jonas S

“…Real-world evaluation studies have shown that many patients with asthma remain symptomatic despite treatment with inhaled corticosteroids (ICSs). As…”
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Mast cells from different molecular and prognostic subtypes of systemic mastocytosis display distinct immunophenotypes by Teodosio, Cristina, MSc, García-Montero, Andrés C., PhD, Jara-Acevedo, María, MSc, Sánchez-Muñoz, Laura, MD, PhD, Álvarez-Twose, Ivan, MD, Núñez, Rosa, MD, Schwartz, Lawrence B., MD, PhD, Walls, Andrew F., PhD, Escribano, Luis, MD, PhD, Orfao, Alberto, MD, PhD

“…Background Systemic mastocytosis (SM) is a heterogeneous group of disorders with distinct clinical and biological behavior. Despite this, little is known about…”
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Mast cell Tryptase and Carboxypeptidase A3 (CPA3) as Markers for Predicting Susceptibility to Severe Allergic Drug Reactions by Abadalkareem, Rana, MBBS, Lau, Laurie C.K., PhD, Abdelmotelb, Ahmed, PhD, Zhou, Xiaoying, PhD, Eren, Efrem, MBBS, PhD, Walls, Andrew F., PhD, FAAAAI

“…Sensitive enzyme linked immunosorbent assays (ELISA) were developed and validated, using specific antibodies to tryptase and CPA3 (lower limits of detection of…”
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Identification of Basophils as a Major Source of Hepatocyte Growth Factor in Chronic Myeloid Leukemia: A Novel Mechanism of BCR-ABL1-Independent Disease Progression by Cerny-Reiterer, Sabine, Ghanim, Viviane, Hoermann, Gregor, Aichberger, Karl J, Herrmann, Harald, Muellauer, Leonhard, Repa, Andreas, Sillaber, Christian, Walls, Andrew F, Mayerhofer, Matthias, Valent, Peter

“…Abstract Chronic myeloid leukemia (CML) is a hematopoietic neoplasm characterized by the Philadelphia chromosome and the related BCR-ABL1 oncoprotein…”
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Bradykinin Generation in Acute Allergic Reactions and Angioedema: Roles of Mast Cell Tryptase and Chymase by Zhou, Xiaoying, PhD, Eren, Efrem, MBBS, MRCP, FRCPath, PhD, Rae, William, BSc, BM, MRCP, Walls, Andrew F., PhD, FAAAAI

“…Methods Kininogen cleavage was assessed by Western blotting and SDS PAGE; and bradykinin levels were measured using a competitive immunoassay following…”
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Repeated Amblyomma testudinarium tick bites are associated with increased galactose-α-1,3-galactose carbohydrate IgE antibody levels: A retrospective cohort study in a single institution by Hashizume, Hideo, Fujiyama, Toshiharu, Umayahara, Takatsune, Kageyama, Reiko, Walls, Andrew F., Satoh, Takahiro

“…Alpha-gal syndrome is a hypersensitivity reaction to red meat mediated by IgE antibody specific to galactose-α-1,3-galactose carbohydrate (alpha-gal)…”
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Modulation of basophil activity: A novel function of the neuropeptide α-melanocyte–stimulating hormone by Böhm, Markus, MD, Apel, Mara, Sugawara, Koji, MD, Brehler, Randolf, MD, Jurk, Kerstin, PhD, Luger, Thomas A., MD, Haas, Helmut, PhD, Paus, Ralf, MD, Eiz-Vesper, Britta, MD, Walls, Andrew F., PhD, Ponimaskin, Evgeni, PhD, Gehring, Manuela, Kapp, Alexander, MD, Raap, Ulrike, MD

“…Background Little is known about the effect of neuropeptides on basophils, which are important effector cells in immune and allergic responses. Objective This…”
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Segmental Bronchoprovocation in Allergic Rhinitis Patients Affects Mast Cell and Basophil Numbers in Nasal and Bronchial Mucosa by BRAUNSTAHL, GERT-JAN, OVERBEEK, SHELLEY E, FOKKENS, WYTSKE J, KLEINJAN, ALEX, MCEUEN, ALAN R, WALLS, ANDREW F, HOOGSTEDEN, HENK C, PRINS, JAN-BAS

“…Mast cells and basophils are cells that play an important role in the initiation and control of allergic inflammation in asthma and rhinitis. This study was…”
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Tryptase‐stimulated human airway smooth muscle cells induce cytokine synthesis and mast cell Chemotaxis by Berger, Patrick, Girodet, Pierre-Olivier, Begueret, Hugues, Ousova, Olga, Perng, Diahn-Warng, Marthan, Roger, Walls, Andrew F., Lara, J. Manuel Tunon

“…ABSTRACT Asthmatic patients have higher numbers of mast cells in the smooth muscle layer of airways than normal subjects. Human airway smooth muscle cells…”
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Detection of Mast Cells and Basophils by Immunohistochemistry by Walls, Andrew F, Amalinei, Cornelia

“…Staining cells or tissues with basic dyes was the mainstay of mast cell and basophil detection methods for more than a century following the first…”
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A mechanistic multicentre, parallel group, randomised placebo-controlled trial of mesalazine for the treatment of IBS with diarrhoea (IBS-D) by Lam, Ching, Tan, Wei, Leighton, Matthew, Hastings, Margaret, Lingaya, Melanie, Falcone, Yirga, Zhou, Xiaoying, Xu, Luting, Whorwell, Peter, Walls, Andrew F, Zaitoun, Abed, Montgomery, Alan, Spiller, Robin

“…Immune activation has been reported in the mucosa of IBS patients with diarrhoea (IBS-D), and some small studies have suggested that mesalazine may reduce…”
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Cutaneous basophil infiltration in atopic dermatitis is associated with abundant epidermal infiltration of helper T cells: A preliminary retrospective study by Nagashima, Natsumi, Ugajin, Tsukasa, Miyake, Kensuke, Walls, Andrew F., Namiki, Takeshi, Yokozeki, Hiroo, Karasuyama, Hajime, Okiyama, Naoko

“…Atopic dermatitis (AD) is a heterogenous inflammatory skin disorder. Our previous study revealed that basophil infiltration in skin is observed in…”
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