Search Results - "WALL, Randolph"
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Somatic Hypermutation of the B Cell Receptor Genes B29 (Igβ, CD79b) and mb1 (Igα, CD79a)
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-2003)“…Somatic hypermutation (SHM), coupled to selection by antigen, generates high-affinity antibodies during germinal center (GC) B cell maturation. SHM is known to…”
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2
Patterned CpG Methylation of Silenced B Cell Gene Promoters in Classical Hodgkin Lymphoma-derived and Primary Effusion Lymphoma Cell Lines
Published in Journal of molecular biology (22-07-2005)“…Hodgkin and Reed–Sternberg (HRS) cells of classical Hodgkin lymphoma (cHL) and primary effusion lymphoma (PEL) are derived from germinal center (GC) and…”
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3
Dysregulated TCL1 Promotes Multiple Classes of Mature B Cell Lymphoma
Published in Proceedings of the National Academy of Sciences - PNAS (29-10-2002)“…The TCL1 protooncogene is overexpressed in many mature B cell lymphomas, especially from AIDS patients. To determine whether aberrant expression promotes B…”
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4
TORC2 Regulates Germinal Center Repression of the TCL1 Oncoprotein to Promote B Cell Development and Inhibit Transformation
Published in Proceedings of the National Academy of Sciences - PNAS (12-06-2007)“…Aberrant expression of the TCL1 oncoprotein promotes malignant transformation of germinal center (GC) B cells. Repression of TCL1 in GC B cells facilitates…”
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5
TCL1 oncogene expression in B cell subsets from lymphoid hyperplasia and distinct classes of B cell lymphoma
Published in Laboratory investigation (01-04-2001)“…Activation of the TCL1 oncogene has been implicated in T cell leukemias/lymphomas and recently was associated with AIDS diffuse large B cell lymphomas…”
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6
Syndecan-4 Is Expressed by B Lineage Lymphocytes and Can Transmit a Signal for Formation of Dendritic Processes
Published in The Journal of immunology (1950) (15-05-1999)“…Our previous studies indicated that stromal cell-derived syndecan-4 might mediate some form of communication with pre-B cells in bone marrow. We now report…”
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7
TCL1 Oncogene Expression in AIDS-Related Lymphomas and Lymphoid Tissues
Published in Proceedings of the National Academy of Sciences - PNAS (17-08-1999)“…AIDS-related non-Hodgkin's lymphoma (AIDS NHL) comprises a diverse and heterogeneous group of high-grade B cell tumors. Certain classes of AIDS NHL are…”
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8
Sp1 Transactivation of the TCL1 Oncogene
Published in The Journal of biological chemistry (10-01-2003)“…Cis-regions and trans-factors controllingTCL1 oncogene expression are not known. We identified the functional TCL1 promoter by mapping four transcriptional…”
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9
Aberrant B Cell Receptor Signaling from B29 (Igβ , CD79b) Gene Mutations of Chronic Lymphocytic Leukemia B Cells
Published in Proceedings of the National Academy of Sciences - PNAS (09-05-2000)“…Chronic lymphocytic leukemia (CLL) B cells characteristically exhibit low or undetectable surface B cell receptor (BCR) and diminished responses to…”
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10
Silencer Elements Controlling the B29 (Igβ ) Promoter are Neither Promoter- nor Cell-Type-Specific
Published in Proceedings of the National Academy of Sciences - PNAS (11-11-1997)“…The murine B29 (Igβ ) promoter is B cell specific and contains essential SP1, ETS, OCT, and Ikaros motifs. Flanking 5′DNA sequences inhibit B29 promoter…”
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11
CmC(A/T)GG DNA Methylation in Mature B Cell Lymphoma Gene Silencing
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2001)“…DNA methylation has been linked to gene silencing in cancer. Primary effusion lymphoma (PEL) and myeloma are lymphoid malignancies that arise from terminally…”
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12
Photothermal Nanoblade for Large Cargo Delivery into Mammalian Cells
Published in Analytical chemistry (Washington) (15-02-2011)“…It is difficult to achieve controlled cutting of elastic, mechanically fragile, and rapidly resealing mammalian cell membranes. Here, we report a photothermal…”
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13
PKC-β controls IκB kinase lipid raft recruitment and activation in response to BCR signaling
Published in Nature immunology (01-08-2002)“…NF-kappa B signaling is required for the maintenance of normal B lymphocytes, whereas dysregulated NF-kappa B activation contributes to B cell lymphomas. The…”
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14
Domains and the hinge region of an immunoglobulin heavy chain are encoded in separate DNA segments
Published in Nature (London) (22-02-1979)“…A 6.8-kilobase DNA fragment containing the sequence coding for the constant region of the mouse immunoglobulin gamma1 heavy chain was cloned from total…”
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15
Candidate genes contributing to the aggressive phenotype of mantle cell lymphoma
Published in Acta histochemica (01-11-2011)“…Mantle cell lymphoma and small lymphocytic lymphoma are lymphocyte cancers that have similar morphologies and a common age of onset. Mantle cell lymphoma is…”
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16
Bob1 (OCA-B/OBF-1) Differential Transactivation of the B Cell-Specific B29 (Ig{beta}) and mb-1 (Ig{alpha}) Promoters
Published in The Journal of immunology (1950) (01-04-2002)“…The B29 (Igbeta) and mb-1 (Igalpha) gene products are B cell-specific essential components of the B cell receptor that are coexpressed at all stages of B cell…”
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17
Secondary Teacher and Mental Health Professional Views of Students With School Adjustment Problems
Published in Professional psychology, research and practice (01-12-1985)“…The purpose of this study was to investigate and compare secondary teachers' and mental health professionals' views regarding the urgency of various types of…”
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18
Interleukin-6 signals activating junB and TIS11 gene transcription in a B-cell hybridoma
Published in Molecular and Cellular Biology (01-03-1991)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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19
B29 Gene Silencing in Pituitary Cells Is Regulated by Its 3′ Enhancer
Published in Journal of molecular biology (15-09-2006)“…B cell-specific B29 ( Igβ, CD79b) genes in rat, mouse, and human are situated between the 5′ growth hormone (GH) locus control region and the 3′ GH gene…”
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20
Aberrations of the B-cell receptor B29 (CD79b) gene in chronic lymphocytic leukemia
Published in Blood (15-08-1997)“…Leukemic B cells in chronic lymphocytic leukemia (B-CLL) typically exhibit low or undetectable surface Ig. Because the B29 (CD79b and Ig beta) and mb-1 (CD79a…”
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