Search Results - "WALKER, Robert C"

The AUGIS Survival Predictor: Prediction of Long-Term and Conditional Survival After Esophagectomy Using Random Survival Forests by Rahman, Saqib A, Walker, Robert C, Maynard, Nick, Trudgill, Nigel, Crosby, Tom, Cromwell, David A, Underwood, Timothy J

“…The aim of this study was to develop a predictive model for overall survival after esophagectomy using pre/postoperative clinical data and machine learning…”
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Comparison of optimized methodologies for isolating nuclei from esophageal tissue by Kimbley, Lucy M, Parker, Rachel, Harrington, Jack, Walker, Robert C, Grace, Ben, West, Jonathan J, Underwood, Tim J, Rose-Zerilli, Matthew Jj

“…Single-nuclei RNA sequencing allows single cell-based analysis in frozen tissue, ameliorating cell recovery biases associated with enzymatic dissociation…”
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Stably Expressed APOBEC3F Has Negligible Antiviral Activity by MIYAGI, Eri, BROWN, Charles R, OPI, Sandrine, KHAN, Mohammad, GOILA-GAUR, Ritu, KAO, Sandra, WALKER, Robert C, HIRSCH, Vanessa, STREBEL, Klaus

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Identification of Dominant Negative Human Immunodeficiency Virus Type 1 Vif Mutants That Interfere with the Functional Inactivation of APOBEC3G by Virus-Encoded Vif by WALKER, Robert C, KHAN, Mohammad A, KAO, Sandra, GOILA-GAUR, Ritu, MIYAGI, Eri, STREBEL, Klaus

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Encapsidation of APOBEC3G into HIV-1 virions involves lipid raft association and does not correlate with APOBEC3G oligomerization by Khan, Mohammad A, Goila-Gaur, Ritu, Kao, Sandra, Miyagi, Eri, Walker, Jr, Robert C, Strebel, Klaus

“…The cellular cytidine deaminase APOBEC3G (A3G), when incorporated into the human immunodeficiency virus type 1 (HIV-1), renders viral particles non-infectious…”
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Identification of neoantigens in oesophageal adenocarcinoma by Nicholas, Ben, Bailey, Alistair, McCann, Katy J., Wood, Oliver, Walker, Robert C., Parker, Robert, Ternette, Nicola, Elliott, Tim, Underwood, Tim J., Johnson, Peter, Skipp, Paul

“…Oesophageal adenocarcinoma (OAC) has a relatively poor long‐term survival and limited treatment options. Promising targets for immunotherapy are short peptide…”
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Association of Upper Gastrointestinal Surgery of Great Britain and Ireland (AUGIS)/perioperative quality initiative (POQI) consensus statement on prehabilitation in oesophagogastric surgery by Walker, Robert C, Barman, Sowrav, Pucher, Philip H, Singh, Pritam, Whyte, Greg, Moore, John, Huddy, Fiona, Evans, Orla, Tham, Gemma, Noor Z, Zainab, Hussey, Juliette, West, Malcolm A, Jack, Sandy, Levett, Denny, Underwood, Timothy J, Gossage, James A, Sultan, Javed, Maynard, Nicholas, Miller, Timothy E, Grocott, Michael P W, Davies, Andrew R

“…Prehabilitation is safe, feasible and may improve a range of outcomes in patients with oesophago-gastric cancer (OGC). Recent studies have suggested the…”
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Residual cancer cells after apparent complete pathological response to neoadjuvant therapy in oesophageal adenocarcinoma by Walker, Robert C, Harrington, Jack, Breininger, Stella P, Pickering, Oliver, Hill, Samuel L, Sharpe, Benjamin P, Grace, Ben, Reddin, Ian, Rajak, Rushda, Manousopoulou, Antigoni, Garbis, Spiros D, Walters, Zoë S, Rose-Zerilli, Matthew J J, Underwood, Timothy J

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Outcomes and survival following neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the esophagus: Inverse propensity score weighted analysis by Pucher, Philip H., Rahman, Saqib A., Walker, Robert C., Grace, Ben L., Bateman, Andrew, Iveson, Tim, Jackson, Andrew, Rees, Charlotte, Byrne, James P., Kelly, Jamie J., Noble, Fergus, Underwood, Timothy J.

“…Esophageal cancer is increasingly common and carries a poor prognosis. The optimal treatment modality for locally advanced cancer is unknown, with current…”
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A 1000-year record of forest fire, drought and lake-level change in southeastern British Columbia, Canada by Hallett, Douglas J., Mathewes, Rolf W., Walker, Robert C.

“…High-resolution charcoal analysis of lake sediments and stand-age information were used to reconstruct a 1000-year fire history around Dog Lake, which is…”
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Genomic Analysis of Response to Neoadjuvant Chemotherapy in Esophageal Adenocarcinoma by Izadi, Fereshteh, Sharpe, Benjamin P, Breininger, Stella P, Secrier, Maria, Gibson, Jane, Walker, Robert C, Rahman, Saqib, Devonshire, Ginny, Lloyd, Megan A, Walters, Zoë S, Fitzgerald, Rebecca C, Rose-Zerilli, Matthew J J, Underwood, Tim J, On Behalf Of Occams

“…Neoadjuvant therapy followed by surgery is the standard of care for locally advanced esophageal adenocarcinoma (EAC). Unfortunately, response to neoadjuvant…”
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Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts by Sharpe, Benjamin P, Hayden, Annette, Manousopoulou, Antigoni, Cowie, Andrew, Walker, Robert C, Harrington, Jack, Izadi, Fereshteh, Breininger, Stella P, Gibson, Jane, Pickering, Oliver, Jaynes, Eleanor, Kyle, Ewan, Saunders, John H, Parsons, Simon L, Ritchie, Alison A, Clarke, Philip A, Collier, Pamela, Mongan, Nigel P, Bates, David O, Yacqub-Usman, Kiren, Garbis, Spiros D, Walters, Zoë, Rose-Zerilli, Matthew, Grabowska, Anna M, Underwood, Timothy J

“…The chemotherapy resistance of esophageal adenocarcinomas (EACs) is underpinned by cancer cell extrinsic mechanisms of the tumor microenvironment (TME). We…”
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The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes by Kazachenka, Anastasiya, Loong, Jane Hc, Attig, Jan, Young, George R, Ganguli, Piyali, Devonshire, Ginny, Grehan, Nicola, Ciccarelli, Francesca D, Fitzgerald, Rebecca C, Kassiotis, George

“…Abstract Most cancer types exhibit aberrant transcriptional activity, including derepression of retrotransposable elements (RTEs). However, the degree,…”
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Oesophageal cancer 2023 by Walker, Robert C., Gossage, James A.

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Oesophageal cancer by Walker, Robert C., Underwood, Timothy J.

“…Oesophageal cancer is a lethal condition where 5-year survival remains at about 15%. There are two main subtypes of oesophageal cancer, squamous cell carcinoma…”
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Uronide deposition rates in the primary root of Zea mays [Maize, mathematical models] by Silk, Wendy Kuhn, Robert C. Walker, John Labavitch

“…The spatial distribution of the rate of deposition of uronic acids in the elongation zone of Zea mays L. Crow WF9 × Mo 17 was determined using the continuity…”
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An International Multicenter Study Exploring Whether Surveillance After Esophageal Cancer Surgery Impacts Oncological and Quality of Life Outcomes (ENSURE) by Elliott, Jessie A., Markar, Sheraz R., Klevebro, Fredrik, Johar, Asif, Goense, Lucas, Lagergren, Pernilla, Zaninotto, Giovanni, van Hillegersberg, Richard, Henegouwen, Mark I. van Berge, Nilsson, Magnus, Hanna, George B., Reynolds, John V.

“…To determine the impact of surveillance on recurrence pattern, treatment, survival and health-related quality-of-life (HRQL) following curative-intent…”
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Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett's oesophagus surveillance: individual-level data analysis by Black, Emily L, Ococks, Emma, Devonshire, Ginny, Ng, Alvin Wei Tian, O'Donovan, Maria, Malhotra, Shalini, Tripathi, Monika, Miremadi, Ahmad, Freeman, Adam, Coles, Hannah, Fitzgerald, Rebecca C

“…Whether gastric metaplasia (GM) of the oesophagus should be considered as Barrett's oesophagus (BO) is controversial. Given concern intestinal metaplasia (IM)…”
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Oesophageal cancer by Walker, Robert C., Underwood, Timothy J.

“…There are two main types of oesophageal cancer, squamous cell carcinoma (SCC) and adenocarcinoma (ACA). SCC usually affects the middle third of the oesophagus…”
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Disentangling oncogenic amplicons in esophageal adenocarcinoma by Ng, Alvin Wei Tian, McClurg, Dylan Peter, Wesley, Ben, Zamani, Shahriar A., Black, Emily, Miremadi, Ahmad, Giger, Olivier, Hoopen, Rogier ten, Devonshire, Ginny, Redmond, Aisling M., Grehan, Nicola, Jammula, Sriganesh, Blasko, Adrienn, Li, Xiaodun, Aparicio, Samuel, Tavaré, Simon, Nowicki-Osuch, Karol, Fitzgerald, Rebecca C.

“…Esophageal adenocarcinoma is a prominent example of cancer characterized by frequent amplifications in oncogenes. However, the mechanisms leading to amplicons…”
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