Search Results - "WALES, J. K"

Expanding the Clinical Spectrum Associated With GLIS3 Mutations by Dimitri, P, Habeb, A. M, Garbuz, F, Millward, A, Wallis, S, Moussa, K, Akcay, T, Taha, D, Hogue, J, Slavotinek, A, Wales, J. K. H, Shetty, A, Hawkes, D, Hattersley, A. T, Ellard, S, De Franco, E

“…Context: GLIS3 (GLI-similar 3) is a member of the GLI-similar zinc finger protein family encoding for a nuclear protein with 5 C2H2-type zinc finger domains…”
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Adipokines, bone-derived factors and bone turnover in obese children; evidence for altered fat-bone signalling resulting in reduced bone mass by Dimitri, P, Wales, J.K, Bishop, N

“…Abstract Obese children, particularly those who have fractured, have reduced body size-adjusted total body and regional bone mass. We performed an…”
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Effectiveness of the Kids in Control of Food (KICk-OFF) structured education course for 11-16 year olds with Type 1 diabetes by Price, K. J., Knowles, J. A., Fox, M., Wales, J. K. H., Heller, S., Eiser, C., Freeman, J. V.

“…Aim To assess the effect of a 5–day structured education course (Kids in Control of Food; KICk–OFF) on biomedical and psychological outcomes in young people…”
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Novel GLIS3 mutations demonstrate an extended multisystem phenotype by Dimitri, P, Warner, J T, Minton, J A L, Patch, A M, Ellard, S, Hattersley, A T, Barr, S, Hawkes, D, Wales, J K, Gregory, J W

“…IntroductionMutations in the GLI-similar 3 (GLIS3) gene encoding the transcription factor GLIS3 are a rare cause of neonatal diabetes and congenital…”
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Stomatocytic haemolysis and macrothrombocytopenia (Mediterranean stomatocytosis/macrothrombocytopenia) is the haematological presentation of phytosterolaemia by Rees, David C., Iolascon, Achille, Carella, Massimo, O'Marcaigh, Aengus S., Kendra, James R., Jowitt, Simon N., Wales, J. K., Vora, Ajay, Makris, M., Manning, Nigel, Nicolaou, Anna, Fisher, Julie, Mann, Anuska, Machin, Samuel J., Clayton, Peter T., Gasparini, Paolo, Stewart, Gordon W.

“…Summary Phytosterolaemia (sitosterolaemia) is a recessively inherited metabolic condition in which the absorption of both cholesterol and plant‐derived…”
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Very low birth weight survivors have reduced peak bone mass and reduced insulin sensitivity by Smith, C. M., Wright, N. P., Wales, J. K. H., Mackenzie, C., Primhak, R. A., Eastell, R., Walsh, J. S.

“…Summary Context  Increasing numbers of very low birth weight (VLBW) infants are surviving into adulthood because of improvements in neonatal intensive care…”
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Adrenal insufficiency in phytosterolaemia by Mushtaq, T, Wales, J K, Wright, N P

“…Background: Phytosterolaemia (sitosterolaemia) is a rare autosomal recessive condition caused by mutations on the ABCG5 and ABCG8 gut transporter proteins…”
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Symptomatic adrenal insufficiency during inhaled corticosteroid treatment by Patel, L, Wales, J K, Kibirige, M S, Massarano, A A, Couriel, J M, Clayton, P E

“…Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously…”
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Intragastric balloon as an adjunct to lifestyle programme in severely obese adolescents: impact on biomedical outcomes and skeletal health by Sachdev, P, Reece, L, Thomson, M, Natarajan, A, Copeland, R J, Wales, J K, Wright, N P

“…Intragastric Balloons are a temporary, reversible and safer option compared to bariatric surgery to promote significant weight loss, leading to improved…”
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Intra-gastric balloon as an adjunct to lifestyle support in severely obese adolescents; impact on weight, physical activity, cardiorespiratory fitness and psychosocial well-being by Reece, L J, Sachdev, P, Copeland, R J, Thomson, M, Wales, J K, Wright, N P

“…Background: Severe adolescent obesity (body mass index (BMI) >99.6th centile) is a significant public health challenge. Current non-invasive treatments,…”
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Dietary fat and appetite control in obese subjects: weak effects on satiation and satiety by Lawton, C L, Burley, V J, Wales, J K, Blundell, J E

“…The present study assessed the capacity of both high fat and high carbohydrate (CHO) foods to lead to overconsumption in 12 obese women (mean BMI = 42 kg/m2)…”
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Adult height of preterm infants: a longitudinal cohort study by Ferguson, E C, Wright, N P, Gibson, A T, Carney, S, Wright, A, Wales, J K

“…BackgroundMany infants born prematurely experience growth failure following delivery, with subsequent catch-up growth. Traditionally catch-up was thought to be…”
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Comparison of high-fat and high-carbohydrate foods in a meal or snack on short-term fat and energy intakes in obese women by Green, S. M., Wales, J. K., Lawton, C. L., Blundell, J. E.

“…The present study aimed to compare the action of high-fat and high-carbohydrate (CHO) foods on meal size (satiation) and post-meal satiety in obese women. A…”
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Does psychological stress cause diabetes? by Wales, J K

“…Many patients believe that their diabetes has been caused by stress or an adverse life event. Whereas there is strong evidence that psychological stress is…”
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Fluoxetine in the treatment of obese type 2 diabetic patients by O'Kane, M, Wiles, P G, Wales, J K

“…In a 12-month randomly allocated double-blind trial in 19 obese Type 2 diabetic patients, fluoxetine 60 mg daily compared to placebo produced a significant…”
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Monitoring serum insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3), IGF-I/IGFBP-3 molar ratio and leptin during growth hormone treatment for disordered growth by TILLMANN, V, PATEL, L, GILL, M. S, WHATMORE, A. J, PRICE, D. A, KIBIRIGE, M. S, WALES, J. K, CLAYTON, P. E

“…OBJECTIVE Serum IGF‐I levels are monitored during GH replacement treatment in adults with GH deficiency (GHD) to guide GH dose adjustment and to minimize…”
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Risk factors for coronary heart disease in obese non-diabetic subjects by WHITELAW, D. C, O'KANE, M, WALES, J. K, BARTH, J. H

“…To examine relationships between body mass index (BMI) and coronary risk factors in obese subjects presenting to a dedicated obesity clinic. Cross-sectional…”
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Letter in response to Chitale et al.: determining the utility of the 60-minute cortisol measurement in the short synacthen test by Elder, C. J., Somerset, L. M., Ram, V., Wright, N. P., Wales, J. K., Dimitri, P. J.

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Pubertal growth in young adult survivors of childhood leukemia by Didcock, E, Davies, H A, Didi, M, Ogilvy Stuart, A L, Wales, J K, Shalet, S M

“…To determine the effect of cranial irradiation (18 Gy and 24 Gy) on pubertal growth in young adult survivors of childhood acute lymphoblastic leukemia (ALL)…”
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IGF-I and IGF-binding protein-3 measurements on filter paper blood spots in children and adolescents on GH treatment: use in monitoring and as markers of growth performance by Das, U, Whatmore, AJ, Khosravi, J, Wales, JK, Butler, G, Kibirige, MS, Diamandi, A, Jones, J, Patel, L, Hall, CM, Price, DA, Clayton, PE

“…BACKGROUND/AIM: In childhood an appropriate response to GH treatment is achieved by titration of growth response against dose administered, with careful…”
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