Search Results - "WAKUI, MASATOSHI"

The reconstituted ‘humanized liver’ in TK-NOG mice is mature and functional by Hasegawa, Masami, Kawai, Kenji, Mitsui, Tetsuya, Taniguchi, Kenji, Monnai, Makoto, Wakui, Masatoshi, Ito, Mamoru, Suematsu, Makoto, Peltz, Gary, Nakamura, Masato, Suemizu, Hiroshi

“…► A novel experimental in vivo platform for replacing mouse liver with human cells. Administration of GCV ablates the liver of HSVtk transgenic immunodeficient…”
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The effect of the E484K mutation of SARS-CoV-2 on the neutralizing activity of antibodies from BNT162b2 vaccinated individuals by Uwamino, Yoshifumi, Yokoyama, Takashi, Shimura, Takako, Nishimura, Tomoyasu, Sato, Yasunori, Wakui, Masatoshi, Kosaki, Kenjiro, Hasegawa, Naoki, Murata, Mitsuru

“…•Neutralization antibody were measured against SARS-CoV-2 variants after vaccination.•Low neutralization antibody titer was observed against beta and delta…”
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Dynamics of antibody titers and cellular immunity among Japanese healthcare workers during the 6 months after receiving two doses of BNT162b2 mRNA vaccine by Uwamino, Yoshifumi, Kurafuji, Toshinobu, Takato, Kumiko, Sakai, Akiko, Tanabe, Akiko, Noguchi, Masayo, Yatabe, Yoko, Arai, Tomoko, Ohno, Akemi, Tomita, Yukari, Shibata, Ayako, Yokota, Hiromitsu, Yamasawa, Wakako, Namkoong, Ho, Sato, Yasunori, Hasegawa, Naoki, Wakui, Masatoshi, Murata, Mitsuru

“…The antibody titer is known to wane within months after receiving two doses of the Pfizer-BioNTech BNT162b2 mRNA SARS-CoV-2 vaccine. However, knowledge of the…”
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Association of systemic adverse reaction patterns with long-term dynamics of humoral and cellular immunity after coronavirus disease 2019 third vaccination by Yoshida, Makoto, Kobashi, Yurie, Kawamura, Takeshi, Shimazu, Yuzo, Nishikawa, Yoshitaka, Omata, Fumiya, Saito, Hiroaki, Yamamoto, Chika, Zhao, Tianchen, Takita, Morihiro, Ito, Naomi, Tatsuno, Kenji, Kaneko, Yudai, Nakayama, Aya, Kodama, Tatsuhiko, Wakui, Masatoshi, Takahashi, Kenzo, Tsubokura, Masaharu

“…The objective of this study was to clarify the impact of adverse reactions on immune dynamics. We investigated the pattern of systemic adverse reactions after…”
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Evaluation of the usability of various rapid antibody tests in the diagnostic application for COVID-19 by Uwamino, Yoshifumi, Wakui, Masatoshi, Aoki, Wataru, Kurafuji, Toshinobu, Yanagita, Emmy, Morita, Maasa, Nagata, Mika, Inose, Rika, Noguchi, Masayo, Yokota, Hiromitsu, Hasegawa, Naoki, Saya, Hideyuki, Murata, Mitsuru

“…The usability of laboratory tests related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critically important for the world undergoing the…”
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Five doses of the mRNA vaccination potentially suppress ancestral-strain stimulated SARS-CoV2-specific cellular immunity: a cohort study from the Fukushima vaccination community survey, Japan by Tani, Yuta, Takita, Morihito, Wakui, Masatoshi, Saito, Hiroaki, Nishiuchi, Takamitsu, Zhao, Tianchen, Yamamoto, Chika, Kawamura, Takeshi, Sugiyama, Akira, Nakayama, Aya, Kaneko, Yudai, Kodama, Tatsuhiko, Shinaha, Ryuzaburo, Tsubokura, Masaharu

“…The bivalent mRNA vaccine is recommended to address coronavirus disease variants, with additional doses suggested for high-risk groups. However, the…”
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Assessment of in vitro effects of direct thrombin inhibitors and activated factor X inhibitors through clot waveform analysis by Wakui, Masatoshi, Fujimori, Yuta, Katagiri, Hisako, Nakamura, Shoko, Kondo, Yoshino, Kuroda, Yuko, Nakagawa, Terumichi, Shimizu, Nobuko, Murata, Mitsuru

“…Clot waveform analysis (CWA) has been reported to extend the interpretation of clotting time measurement. The parameters obtained from successive derivatives…”
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SARS-CoV-2 spike protein antibody titers after the fourth dose of BNT162b2 vaccine among Japanese patients undergoing hemodialysis: a single-center study by Watanabe, Shun, Sawano, Toyoaki, Saito, Hiroaki, Ozaki, Akihiko, Wakui, Masatoshi, Zhao, Tianchen, Yamamoto, Chika, Kobashi, Yurie, Kawamura, Takeshi, Sugiyama, Akira, Nakayama, Aya, Kaneko, Yudai, Shimmura, Hiroaki, Tsubokura, Masaharu

“…Patients undergoing hemodialysis are particularly vulnerable to severe outcomes of SARS-CoV-2 infection, with mortality rates higher than that of the general…”
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Amino acid catabolite markers for early prognostication of pneumonia in patients with COVID-19 by Maeda, Rae, Seki, Natsumi, Uwamino, Yoshifumi, Wakui, Masatoshi, Nakagama, Yu, Kido, Yasutoshi, Sasai, Miwa, Taira, Shu, Toriu, Naoya, Yamamoto, Masahiro, Matsuura, Yoshiharu, Uchiyama, Jun, Yamaguchi, Genki, Hirakawa, Makoto, Kim, Yun-Gi, Mishima, Masayo, Yanagita, Motoko, Suematsu, Makoto, Sugiura, Yuki

“…Effective early-stage markers for predicting which patients are at risk of developing SARS-CoV-2 infection have not been fully investigated. Here, we performed…”
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Validation of chemiluminescent enzyme immunoassay in detection of autoantibodies in pemphigus and pemphigoid by Fujio, Yumi, Kojima, Kazuo, Hashiguchi, Masahiro, Wakui, Masatoshi, Murata, Mitsuru, Amagai, Masayuki, Yamagami, Jun

“…Highlights • A novel serological assay for autoantibodies in pemphigus and pemphigoid…”
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Response kinetics of different classes of antibodies to SARS-CoV2 infection in the Japanese population: The IgA and IgG titers increased earlier than the IgM titers by Kurano, Makoto, Morita, Yoshifumi, Nakano, Yuki, Yokoyama, Rin, Shimura, Takuya, Qian, Chungen, Xia, Fuzhen, He, Fan, Zheng, Liang, Ohmiya, Hiroko, Kishi, Yoshiro, Okada, Jun, Yoshikawa, Naoyuki, Nakajima, Kazuki, Nagura, Yutaka, Okazaki, Hitoshi, Jubishi, Daisuke, Moriya, Kyoji, Seto, Yasuyuki, Yasui, Fumihiko, Kohara, Michinori, Wakui, Masatoshi, Kawamura, Takeshi, Kodama, Tatsuhiko, Yatomi, Yutaka

“…•Serial antibody measurement is necessary to understand the immunity in COVID-19.•IgA was generated more rapidly against all the viral proteins than IgM and…”
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Diminished neutralizing activity against the XBB1.5 strain in 55.9% of individuals post 6 months COVID-19 mRNA booster vaccination: insights from a pseudovirus assay on 1,353 participants in the Fukushima vaccination community survey, Japan by Zhao, Tianchen, Tani, Yuta, Makino-Okamura, Chieko, Takita, Morihito, Yamamoto, Chika, Kawahara, Eiki, Abe, Toshiki, Sugiura, Sota, Yoshimura, Hiroki, Uchiyama, Taiga, Yamazaki, Isato, Ishigame, Harumichi, Ueno, Takaharu, Okuma, Kazu, Wakui, Masatoshi, Fukuyama, Hidehiro, Tsubokura, Masaharu

“…This study investigates the neutralizing activity against the XBB1.5 variant and the ancestral strain in a population post-bivalent vaccination using a pseudo…”
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Effect of refrigeration of blood samples in lithium-heparin tubes on QuantiFERON TB Gold Plus test result by Uwamino, Yoshifumi, Sakai, Akiko, Nishimura, Tomoyasu, Noguchi, Masayo, Uno, Shunsuke, Fujiwara, Hiroshi, Mori, Masaaki, Wakui, Masatoshi, Murata, Mitsuru, Hasegawa, Naoki

“…The QuantiFERON TB Gold Plus (QFT-Plus) test is a newly approved interferon-gamma releasing assay test for detecting latent tuberculosis. Although blood…”
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The influence of donor age on liver regeneration and hepatic progenitor cell populations by Ono, Yoshihiro, MD, Kawachi, Shigeyuki, MD, PhD, Hayashida, Tetsu, MD, PhD, Wakui, Masatoshi, MD, PhD, Tanabe, Minoru, MD, PhD, Itano, Osamu, MD, PhD, Obara, Hideaki, MD, PhD, Shinoda, Masahiro, MD, PhD, Hibi, Taizo, MD, PhD, Oshima, Go, MD, Tani, Noriyuki, MD, Mihara, Kisyo, MD, Kitagawa, Yuko, MD, PhD

“…Background Recent reports suggest that donor age might have a major impact on recipient outcome in adult living donor liver transplantation (LDLT), but the…”
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Application of clot‐fibrinolysis waveform analysis to assessment of in vitro effects of direct oral anticoagulants on fibrinolysis by Oka, Shusaku, Wakui, Masatoshi, Fujimori, Yuta, Kuroda, Yuko, Nakamura, Shoko, Kondo, Yoshino, Nakagawa, Terumichi, Katagiri, Hisako, Murata, Mitsuru

“…Introduction Acceleration of fibrinolysis by direct oral anticoagulants (DOACs) has been reported by several groups, suggesting contribution of not only…”
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Evaluation of anticoagulant effects of direct thrombin inhibitors, dabigatran and argatroban, based on the Lineweaver-Burk plot applied to the Clauss assay by Fujimori, Yuta, Wakui, Masatoshi, Katagiri, Hisako, Ohira, Kentaro, Shimizu, Nobuko, Murata, Mitsuru

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Analysis of single nucleotide polymorphisms (SNPs) by Wakui, Masatoshi

“…Single nucleotide polymorphisms (SNPs) are DNA sequence variations occurring when a single nucleotide in the genome differs in paired chromosomes. Some SNPs in…”
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Polysulfide Serves as a Hallmark of Desmoplastic Reaction to Differentially Diagnose Ductal Carcinoma In Situ and Invasive Breast Cancer by SERS Imaging by Kubo, Akiko, Masugi, Yohei, Hase, Takeshi, Nagashima, Kengo, Kawai, Yuko, Takizawa, Minako, Hishiki, Takako, Shiota, Megumi, Wakui, Masatoshi, Kitagawa, Yuko, Kabe, Yasuaki, Sakamoto, Michiie, Yachie, Ayako, Hayashida, Tetsu, Suematsu, Makoto

“…Pathological examination of formalin-fixed paraffin-embedded (FFPE) needle-biopsied samples by certified pathologists represents the gold standard for…”
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Varying Cellular Immune Response against SARS-CoV-2 after the Booster Vaccination: A Cohort Study from Fukushima Vaccination Community Survey, Japan by Tani, Yuta, Takita, Morihito, Kobashi, Yurie, Wakui, Masatoshi, Zhao, Tianchen, Yamamoto, Chika, Saito, Hiroaki, Kawashima, Moe, Sugiura, Sota, Nishikawa, Yoshitaka, Omata, Fumiya, Shimazu, Yuzo, Kawamura, Takeshi, Sugiyama, Akira, Nakayama, Aya, Kaneko, Yudai, Kodama, Tetsuhiko, Kami, Masahiro, Tsubokura, Masaharu

“…Booster vaccination reduces the incidence of severe cases and mortality related to COVID-19, with cellular immunity playing an important role. However, little…”
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Group of longitudinal adverse event patterns after the fourth dose of COVID-19 vaccination with a latent class analysis by Yamamoto, Chika, Kobashi, Yurie, Kawamura, Takeshi, Nishikawa, Yoshitaka, Saito, Hiroaki, Oguro, Fumiya, Zhao, Tianchen, Takita, Morihito, Sawano, Toyoaki, Ozaki, Akihiko, Abe, Toshiki, Ito, Naomi, Kaneko, Yudai, Nakayama, Aya, Wakui, Masatoshi, Kodama, Tatsuhiko, Tsubokura, Masaharu

“…Vaccination has been implemented as a useful measure to combat the COVID-19 pandemic. However, there is a tendency for individuals to avoid vaccination due to…”
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