Search Results - "WAITUMBI, John N"

Multiplexed Enrichment and Detection of Malarial Biomarkers Using a Stimuli-Responsive Iron Oxide and Gold Nanoparticle Reagent System by Nash, Michael A, Waitumbi, John N, Hoffman, Allan S, Yager, Paul, Stayton, Patrick S

“…There is a need for simple yet robust biomarker and antigen purification and enrichment strategies that are compatible with current rapid diagnostic…”
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Geographic Distribution of Rabies Virus and Genomic Sequence Alignment of Wild and Vaccine Strains, Kenya by Wambugu, Evalyne N, Kimita, Gathii, Kituyi, Sarah N, Washington, Michael A, Masakhwe, Clement, Mutunga, Lucy M, Jaswant, Gurdeep, Thumbi, S M, Schaefer, Brian C, Waitumbi, John N

“…Rabies, a viral disease that causes lethal encephalitis, kills ≈59,000 persons worldwide annually, despite availability of effective countermeasures. Rabies is…”
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Development of a Highly Sensitive Genus-Specific Quantitative Reverse Transcriptase Real-Time PCR Assay for Detection and Quantitation of Plasmodium by Amplifying RNA and DNA of the 18S rRNA Genes by KAMAU, Edwin, TOLBERT, Ladonna S, KORTEPETER, Luke, PRATT, Michael, NYAKOE, Nancy, MURINGO, Linda, OGUTU, Bernard, WAITUMBI, John N, OCKENHOUSE, Christian F

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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High seroprevalence of antibodies against spotted fever and scrub typhus bacteria in patients with febrile Illness, Kenya by Thiga, Jacqueline W, Mutai, Beth K, Eyako, Wurapa K, Ng'ang'a, Zipporah, Jiang, Ju, Richards, Allen L, Waitumbi, John N

“…Serum samples from patients in Kenya with febrile illnesses were screened for antibodies against bacteria that cause spotted fever, typhus, and scrub typhus…”
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Frequency of glucose-6-phosphate dehydrogenase deficiency in malaria patients from six African countries enrolled in two randomized anti-malarial clinical trials by Carter, Nick, Pamba, Allan, Duparc, Stephan, Waitumbi, John N

“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is common in populations living in malaria endemic areas. G6PD genotype and phenotype were determined for…”
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Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya by Ogutu, Bernhards R, Apollo, Odika J, McKinney, Denise, Okoth, Willis, Siangla, Joram, Dubovsky, Filip, Tucker, Kathryn, Waitumbi, John N, Diggs, Carter, Wittes, Janet, Malkin, Elissa, Leach, Amanda, Soisson, Lorraine A, Milman, Jessica B, Otieno, Lucas, Holland, Carolyn A, Polhemus, Mark, Remich, Shon A, Ockenhouse, Christian F, Cohen, Joe, Ballou, W Ripley, Martin, Samuel K, Angov, Evelina, Stewart, V Ann, Lyon, Jeffrey A, Heppner, D Gray, Withers, Mark R

“…The antigen, falciparum malaria protein 1 (FMP1), represents the 42-kDa C-terminal fragment of merozoite surface protein-1 (MSP-1) of the 3D7 clone of P…”
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Characterization of a novel Plasmodium falciparum merozoite surface antigen and potential vaccine target by Niaré, Karamoko, Chege, Timothy, Rosenkranz, Micha, Mwai, Kennedy, Saßmannshausen, Zoe, Odera, Dennis, Nyamako, Lydia, Tuju, James, Alfred, Tiono, Waitumbi, John N, Ogutu, Bernhards, Sirima, Sodiomon B, Awandare, Gordon, Kouriba, Bourema, Rayner, Julian C, Osier, Faith H A

“…Detailed analyses of genetic diversity, antigenic variability, protein localization and immunological responses are vital for the prioritization of novel…”
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Initiation of anti-retroviral/Trimethoprim-Sulfamethoxazole therapy in a longitudinal cohort of HIV-1 positive individuals in Western Kenya rapidly decreases asymptomatic malarial parasitemia by Kifude, Carolyne M, Roberds, Ashleigh, Oyieko, Janet, Ocholla, Stephen, Otieno, Solomon, Waitumbi, John N, Hutter, Jack, Smith, Hunter, Copeland, Nathanial K, Luckhart, Shirley, Stewart, V Ann

“…Interactions between malaria and HIV-1 have important public health implications. Our previous cross-sectional studies showed significant associations between…”
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Females of HbAS genotype have reduced concentration of the malaria protective deoxyhemoglobin S than males by Waitumbi, John N, Kifude, Carolyne M, Hunja, Carol W, Ogutu, Bernhards R

“…The quantity of the intra-erythrocytic deoxyhemoglobin S (Hb S) affects the level of protection against malaria and also the sickling phenomenon. This study…”
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Complement activation by merozoite antigens of Plasmodium falciparum by Korir, Jackson C, Nyakoe, Nancy K, Awinda, George, Waitumbi, John N

“…Complement (C) is a crucial part of the innate immune system and becomes over activated during malaria, resulting in depletion of C components, especially…”
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Evaluation of RTS,S/AS02A and RTS,S/AS01B in adults in a high malaria transmission area by Polhemus, Mark E, Remich, Shon A, Ogutu, Bernhards R, Waitumbi, John N, Otieno, Lucas, Apollo, Stella, Cummings, James F, Kester, Kent E, Ockenhouse, Christian F, Stewart, Ann, Ofori-Anyinam, Opokua, Ramboer, Isabelle, Cahill, Conor P, Lievens, Marc, Dubois, Marie-Claude, Demoitie, Marie-Ange, Leach, Amanda, Cohen, Joe, Ballou, W Ripley, Heppner, Jr, D Gray

“…This study advances the clinical development of the RTS,S/AS01B candidate malaria vaccine to malaria endemic populations. As a primary objective it compares…”
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Seroprevalence of Coxiella burnetii in patients presenting with acute febrile illness at Marigat District Hospital, Baringo County, Kenya by Lemtudo, Allan P., Mutai, Beth K., Mwamburi, Lizzy, Waitumbi, John N.

“…Q fever is not routinely diagnosed in Kenyan hospitals. This study reports on Q fever in patients presenting at Marigat District Hospital, Kenya, with febrile…”
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Plasmodium falciparum DHFR and DHPS Mutations Are Associated With HIV-1 Co-Infection and a Novel DHPS Mutation I504T Is Identified in Western Kenya by Torrevillas, Brandi K, Garrison, Sarah M, McKeeken, Alexander J, Patel, Dharmeshkumar, Van Leuven, James T, Dizon, Nathaniel I, Rivas, Karina I, Hathaway, Nicholas J, Bailey, Jeffrey A, Waitumbi, John N, Kifude, Carolyne M, Oyieko, Janet, Stewart, V Ann, Luckhart, Shirley

“…Antifolate resistance is significant in Kenya and presumed to result from extensive use and cross-resistance between antifolate antimalarials and antibiotics,…”
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Apoptosis stalks Plasmodium falciparum maintained in continuous culture condition by Mutai, Beth K, Waitumbi, John N

“…Growth kinetic of Plasmodium falciparum in culture or in the host fall short of expected growth rate considering that there are 4 x 10(6)/µL red blood cell…”
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COVID-19 mass testing and sequencing: Experiences from a laboratory in Western Kenya by Waitumbi, John N., Omuseni, Esther, Nyataya, Josphat, Masakhwe, Clement, Sigei, Faith, Lemtudo, Allan, Awinda, George, Muthanje, Eric, Andika, Brian, Githii, Rachel, Liyai, Rehema, Kimita, Gathii, Mutai, Beth

“…Background The Basic Science Laboratory (BSL) of the Kenya Medical Research Institute/Walter Reed Project in Kisumu, Kenya addressed mass testing challenges…”
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Enzyme-Linked Immunosorbent Assay for Detection of Plasmodium falciparum Histidine-Rich Protein 2 in Blood, Plasma, and Serum by Kifude, Carolyne M, Rajasekariah, Halli G, Sullivan, Jr, David J, Stewart, V Ann, Angov, Evelina, Martin, Samuel K, Diggs, Carter L, Waitumbi, John N

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Impact of RTS,S/AS02(A) and RTS,S/AS01(B) on genotypes of P. falciparum in adults participating in a malaria vaccine clinical trial by Waitumbi, John N, Anyona, Samuel B, Hunja, Carol W, Kifude, Carolyne M, Polhemus, Mark E, Walsh, Douglas S, Ockenhouse, Chris F, Heppner, D Gray, Leach, Amanda, Lievens, Marc, Ballou, W Ripley, Cohen, Joe D, Sutherland, Colin J

“…RTS,S, a candidate vaccine for malaria, is a recombinant protein expressed in yeast containing part of the circumsporozoite protein (CSP) sequence of 3D7…”
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B-cell activity in children with malaria by Korir, Jackson C, Magambo, Japhet K, Mwatha, Joseph K, Waitumbi, John N

“…Recent studies implicate deficiency of red blood cell (RBC) complement regulatory proteins (CR1 and CD55) in the pathogenesis of malarial anaemia. This study…”
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Complement consumption in children with Plasmodium falciparum malaria by Nyakoe, Nancy K, Taylor, Ronald P, Makumi, Joseph N, Waitumbi, John N

“…Complement (C) can be activated during malaria, C components consumed and inflammatory mediators produced. This has potential to impair host innate defence. In…”
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Age-Related Changes in Red Blood Cell Complement Regulatory Proteins and Susceptibility to Severe Malaria by Waitumbi, John N., Donvito, Béatrice, Kisserli, Aymric, Cohen, Jacques H. M., Stoute, Joseé A.

“…Severe malaria-associated anemia and cerebral malaria are life-threatening complications of Plasmodium falciparum infection. Red blood cell (RBC) complement…”
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