Search Results - "WAIBLER, Zoe"

The Role of Fc Receptors on the Effectiveness of Therapeutic Monoclonal Antibodies by Gogesch, Patricia, Dudek, Simone, van Zandbergen, Ger, Waibler, Zoe, Anzaghe, Martina

“…Since the approval of the first monoclonal antibody (mAb) in 1986, a huge effort has been made to guarantee safety and efficacy of therapeutic mAbs. As of July…”
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Macrophages and Dendritic Cells Are Not the Major Source of Pro-Inflammatory Cytokines Upon SARS-CoV-2 Infection by Niles, Marc A., Gogesch, Patricia, Kronhart, Stefanie, Ortega Iannazzo, Samira, Kochs, Georg, Waibler, Zoe, Anzaghe, Martina

“…The exact role of innate immune cells upon infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and their contribution to the formation…”
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Complement protein C3a enhances adaptive immune responses towards FVIII products by Ringler, Eva, Iannazzo, Samira Ortega, Herzig, Jessica, Weiss, Lisa M, Anzaghe, Martina, Miller, Lilija, Waibler, Zoe

“…The most serious complication in the treatment of hemophilia A (HA) is the development of factor (F)VIII inhibitors or antidrug antibodies (ADA) occurring in…”
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Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia by Kamphuis, Elisabeth, Junt, Tobias, Waibler, Zoe, Forster, Reinhold, Kalinke, Ulrich

“…Early viral infection is often associated with lymphopenia, a transient reduction of blood lymphocyte counts long before the onset of clinical symptoms. We…”
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High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus by Scheuplein, Vivian A, Seifried, Janna, Malczyk, Anna H, Miller, Lilija, Höcker, Lena, Vergara-Alert, Júlia, Dolnik, Olga, Zielecki, Florian, Becker, Björn, Spreitzer, Ingo, König, Renate, Becker, Stephan, Waibler, Zoe, Mühlebach, Michael D

“…The Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as the causative agent of a severe respiratory disease with a fatality rate of…”
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Selective reconstitution of IFN‑γ gene function in Ncr1+ NK cells is sufficient to control systemic vaccinia virus infection by Borst, Katharina, Flindt, Sven, Blank, Patrick, Larsen, Pia-Katharina, Chhatbar, Chintan, Skerra, Jennifer, Spanier, Julia, Hirche, Christoph, König, Martin, Alanentalo, Tomas, Hafner, Martin, Waibler, Zoe, Pfeffer, Klaus, Sexl, Veronika, Sutter, Gerd, Müller, Werner, Graalmann, Theresa, Kalinke, Ulrich

“…IFN-γ is an enigmatic cytokine that shows direct anti-viral effects, confers upregulation of MHC-II and other components relevant for antigen presentation, and…”
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Interleukin-36γ is causative for liver damage upon infection with Rift Valley fever virus in type I interferon receptor-deficient mice by Anzaghe, Martina, Niles, Marc A., Korotkova, Eugenia, Dominguez, Monica, Kronhart, Stefanie, Ortega Iannazzo, Samira, Bechmann, Ingo, Bachmann, Malte, Mühl, Heiko, Kochs, Georg, Waibler, Zoe

“…Type I interferons (IFN) are pro-inflammatory cytokines which can also exert anti-inflammatory effects via the regulation of interleukin (IL)-1 family members…”
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Type I Interferon Supports Inducible Nitric Oxide Synthase in Murine Hepatoma Cells and Hepatocytes and during Experimental Acetaminophen-Induced Liver Damage by Bachmann, Malte, Waibler, Zoe, Pleli, Thomas, Pfeilschifter, Josef, Mühl, Heiko

“…Cytokine regulation of high-output nitric oxide (NO) derived from inducible NO synthase (iNOS) is critically involved in inflammation biology and host defense…”
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TGN1412 Induces Lymphopenia and Human Cytokine Release in a Humanized Mouse Model by Weißmüller, Sabrina, Kronhart, Stefanie, Kreuz, Dorothea, Schnierle, Barbara, Kalinke, Ulrich, Kirberg, Jörg, Hanschmann, Kay-Martin, Waibler, Zoe

“…Therapeutic monoclonal antibodies (mAbs) such as the superagonistic, CD28-specific antibody TGN1412, or OKT3, an anti-CD3 mAb, can cause severe adverse events…”
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Modified Vaccinia Virus Ankara Induces Toll-Like Receptor-Independent Type I Interferon Responses by Waibler, Zoe, Anzaghe, Martina, Ludwig, Holger, Akira, Shizuo, Weiss, Siegfried, Sutter, Gerd, Kalinke, Ulrich

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Glycation of a food allergen by the Maillard reaction enhances its T-cell immunogenicity: Role of macrophage scavenger receptor class A type I and II by Ilchmann, Anne, BSc, Burgdorf, Sven, PhD, Scheurer, Stephan, PhD, Waibler, Zoe, PhD, Nagai, Ryoji, PhD, Wellner, Anne, BSc, Yamamoto, Yasuhiko, MD, PhD, Yamamoto, Hiroshi, MD, PhD, Henle, Thomas, PhD, Kurts, Christian, MD, Kalinke, Ulrich, PhD, Vieths, Stefan, PhD, Toda, Masako, PhD

“…Background The Maillard reaction occurs between reducing sugars and proteins during thermal processing of foods. It produces chemically glycated proteins…”
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Individual combinations of danger signals synergistically increase FVIII product immunogenicity by Miller, Lilija, Klemm, Jessica, Schmidt, Carolin, Hanschmann, Kay‐Martin, Bekeredjian‐Ding, Isabelle, Waibler, Zoe

“…Introduction The most severe side effect in haemophilia A treatment is the development of antifactor VIII antibodies, also called inhibitors. Why inhibitors…”
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Nivolumab Enhances In Vitro Effector Functions of PD-1 + T-Lymphocytes and Leishmania -Infected Human Myeloid Cells in a Host Cell-Dependent Manner by Filippis, Christodoulos, Arens, Katharina, Noubissi Nzeteu, Gaetan Aime, Reichmann, Gabriele, Waibler, Zoe, Crauwels, Peter, van Zandbergen, Ger

“…Functional impairment of T-cells and a concomitant augmented expression of programmed death-1 (PD-1) have been observed in visceral leishmaniasis patients, as…”
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Anti-Tumor Necrosis Factor α Therapeutics Differentially Affect Leishmania Infection of Human Macrophages by Arens, Katharina, Filippis, Christodoulos, Kleinfelder, Helen, Goetzee, Arthur, Reichmann, Gabriele, Crauwels, Peter, Waibler, Zoe, Bagola, Katrin, van Zandbergen, Ger

“…Tumor necrosis factor α (TNFα) drives the pathophysiology of human autoimmune diseases and consequently, neutralizing antibodies (Abs) or Ab-derived molecules…”
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A fusion protein of flagellin and ovalbumin suppresses the TH2 response and prevents murine intestinal allergy by Schülke, Stefan, Burggraf, Manja, Waibler, Zoe, Wangorsch, Andrea, Wolfheimer, Sonja, Kalinke, Ulrich, Vieths, Stefan, Toda, Masako, Scheurer, Stephan

“…The Toll-like receptor (TLR) 5 agonist flagellin is associated with immunomodulatory functions. We sought to investigate whether Listeria monocytogenes–derived…”
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An Attenuated Strain of Human Cytomegalovirus for the Establishment of a Subviral Particle Vaccine by Krauter, Steffi, Büscher, Nicole, Bräuchle, Eric, Ortega Iannazzo, Samira, Penner, Inessa, Krämer, Nadine, Gogesch, Patricia, Thomas, Simone, Kreutz, Marina, Dejung, Mario, Freiwald, Anja, Butter, Falk, Waibler, Zoe, Plachter, Bodo

“…Human cytomegalovirus (HCMV) infection is associated with severe disease conditions either following congenital transmission of the virus or viral reactivation…”
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Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes by Stockinger, Silvia, Kastner, Renate, Kernbauer, Elisabeth, Pilz, Andreas, Westermayer, Sandra, Reutterer, Benjamin, Soulat, Didier, Stengl, Gabriele, Vogl, Claus, Frenz, Theresa, Waibler, Zoe, Taniguchi, Tadatsugu, Rülicke, Thomas, Kalinke, Ulrich, Müller, Mathias, Decker, Thomas

“…Production of type I interferons (IFN-I, mainly IFNalpha and IFNbeta) is a hallmark of innate immune responses to all classes of pathogens. When viral…”
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Prevention of intestinal allergy in mice by rflaA:Ova is associated with enforced antigen processing and TLR5-dependent IL-10 secretion by mDC by Schülke, Stefan, Wolfheimer, Sonja, Gadermaier, Gabriele, Wangorsch, Andrea, Siebeneicher, Susanne, Briza, Peter, Spreitzer, Ingo, Schiller, Dirk, Loeschner, Bettina, Uematsu, Satoshi, Ryffel, Bernard, Akira, Shizuo, Waibler, Zoe, Vieths, Stefan, Toda, Masako, Scheurer, Stephan

“…Conjugated vaccines consisting of flagellin and antigen activate TLR5 and induce strong innate and adaptive immune responses. Objective of the present study…”
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Vaccinia Virus-Mediated Inhibition of Type I Interferon Responses Is a Multifactorial Process Involving the Soluble Type I Interferon Receptor B18 and Intracellular Components by Waibler, Zoe, Anzaghe, Martina, Frenz, Theresa, Schwantes, Astrid, Pöhlmann, Christopher, Ludwig, Holger, Palomo-Otero, Marcos, Alcamí, Antonio, Sutter, Gerd, Kalinke, Ulrich

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Organ-Specific Expression of IL-1 Receptor Results in Severe Liver Injury in Type I Interferon Receptor Deficient Mice by Anzaghe, Martina, Resch, Theresa, Schaser, Elea, Kronhart, Stefanie, Diez, Clara, Niles, Marc A, Korotkova, Eugenia, Schülke, Stefan, Wolfheimer, Sonja, Kreuz, Dorothea, Wingerter, Marion, Bartolomé Rodríguez, María Matilde, Waibler, Zoe

“…Upon treatment with polyinosinic:polycytidylic acid [poly(I:C)], an artificial double-stranded RNA, type I interferon receptor-deficient (IFNAR ) mice develop…”
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