Search Results - "WAGNER, LASZLO"

SGLT2 inhibitor dapagliflozin prevents atherosclerotic and cardiac complications in experimental type 1 diabetes by Hodrea, Judit, Saeed, Adar, Molnar, Agnes, Fintha, Attila, Barczi, Adrienn, Wagner, Laszlo J, Szabo, Attila J, Fekete, Andrea, Balogh, Dora B

“…Cardiovascular disease (CVD) is two to five times more prevalent in diabetic patients and is the leading cause of death. Therefore, identification of novel…”
Get full text

The Sigma-1 Receptor Is a Novel Target for Improving Cold Preservation in Rodent Kidney Transplants by Hosszu, Adam, Toth, Akos R, Lakat, Tamas, Stepanova, Ganna, Antal, Zsuzsanna, Wagner, Laszlo J, Szabo, Attila J, Fekete, Andrea

“…Kidney transplantation is the preferred treatment for patients with end-stage kidney disease. Maintaining organ viability between donation and transplantation,…”
Get full text

RAAS inhibitors directly reduce diabetes‐induced renal fibrosis via growth factor inhibition by Koszegi, Sandor, Molnar, Agnes, Lenart, Lilla, Hodrea, Judit, Balogh, Dora Bianka, Lakat, Tamas, Szkibinszkij, Edgar, Hosszu, Adam, Sparding, Nadja, Genovese, Federica, Wagner, Laszlo, Vannay, Adam, Szabo, Attila J, Fekete, Andrea

“…Key points Increased activation of the renin‐angiotensin‐aldosterone system (RAAS) and elevated growth factor production are of crucial importance in the…”
Get full text

Reduced O -GlcNAcylation and tubular hypoxia contribute to the antifibrotic effect of SGLT2 inhibitor dapagliflozin in the diabetic kidney by Hodrea, Judit, Balogh, Dora B, Hosszu, Adam, Lenart, Lilla, Besztercei, Balazs, Koszegi, Sandor, Sparding, Nadja, Genovese, Federica, Wagner, Laszlo J, Szabo, Attila J, Fekete, Andrea

“…Diabetic kidney disease is a worldwide epidemic, and therapies are incomplete. Clinical data suggest that improved renal outcomes by Na -glucose cotransporter…”
Get more information

Cardioprotective and Antifibrotic Effects of Low-Dose Renin-Angiotensin-Aldosterone System Inhibitors in Type 1 Diabetic Rat Model by Balogh, Dora B, Molnar, Agnes, Degi, Arianna, Toth, Akos, Lenart, Lilla, Saeed, Adar, Barczi, Adrienn, Szabo, Attila J, Wagner, Laszlo J, Reusz, Gyorgy, Fekete, Andrea

“…Diabetic cardiovascular complications are associated with up to 50% mortality, and current therapies are not effective enough. Renin-angiotensin-aldosterone…”
Get full text

An Overview of the Cardioprotective Effects of Novel Antidiabetic Classes: Focus on Inflammation, Oxidative Stress, and Fibrosis by Balogh, Dora Bianka, Wagner, Laszlo Jozsef, Fekete, Andrea

“…Metabolic diseases, particularly diabetes mellitus (DM), are significant global public health concerns. Despite the widespread use of standard-of-care…”
Get full text

Long-term risks after kidney donation: how do we inform potential donors? A survey from DESCARTES and EKITA transplantation working groups by Mjøen, Geir, Maggiore, Umberto, Kessaris, Nicos, Kimenai, Diederik, Watschinger, Bruno, Mariat, Cristophe, Sever, Mehmet Sukru, Crespo, Marta, Peruzzi, Licia, Spasovski, Goce, Sørensen, Søren Schwartz, Heemann, Uwe, Pascual, Julio, Viklicky, Ondrej, Courtney, Aisling E, Hadaya, Karine, Wagner, Laszlo, Nistor, Ionut, Hadjianastassiou, Vassilis, Durlik, Magdalena, Helanterä, Ilkka, Oberbauer, Rainer, Oniscu, Gabriel, Hilbrands, Luuk, Abramowicz, Daniel

“…Abstract Background Publications from the last decade have increased knowledge regarding long-term risks after kidney donation. We wanted to perform a survey…”
Get full text

Aldosterone antagonists in monotherapy are protective against streptozotocin-induced diabetic nephropathy in rats by Banki, Nora F, Ver, Agota, Wagner, Laszlo J, Vannay, Adam, Degrell, Peter, Prokai, Agnes, Gellai, Renata, Lenart, Lilla, Szakal, Dorottya-Nagy, Kenesei, Eva, Rosta, Klara, Reusz, Gyorgy, Szabo, Attila J, Tulassay, Tivadar, Baylis, Chris, Fekete, Andrea

“…Angiotensin converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) are the standard clinical therapy of diabetic nephropathy (DN),…”
Get full text

The role of sigma-1 receptor and brain-derived neurotrophic factor in the development of diabetes and comorbid depression in streptozotocin-induced diabetic rats by Lenart, Lilla, Hodrea, Judit, Hosszu, Adam, Koszegi, Sandor, Zelena, Dora, Balogh, Dora, Szkibinszkij, Edgar, Veres-Szekely, Apor, Wagner, Laszlo, Vannay, Adam, Szabo, Attila J., Fekete, Andrea

“…Rationale Depression is highly prevalent in diabetes (DM). Brain-derived neurotrophic factor (BDNF) which is mainly regulated by the endoplasmic reticulum…”
Get full text

Sexual dimorphism in the aging kidney: Effects on injury and nitric oxide system by Erdely, Aaron, Greenfeld, Ziv, Wagner, Laszlo, Baylis, Chris

“…Sexual dimorphism in the aging kidney: Effects on injury and nitric oxide system. Male gender confers enhanced susceptibility to development of age-dependent…”
Get full text

Na+,K+-ATPase is modulated by angiotensin II in diabetic rat kidney – another reason for diabetic nephropathy? by Fekete, Andrea, Rosta, Klara, Wagner, Laszlo, Prokai, Agnes, Degrell, Peter, Ruzicska, Eva, Vegh, Edit, Toth, Miklos, Ronai, Katalin, Rusai, Krisztina, Somogyi, Aniko, Tulassay, Tivadar, Szabo, Attila J, Ver, Agota

“…Angiotensin II (ANGII) plays a central role in the enhanced sodium reabsorption in early type 1 diabetes in man and in streptozotocin-induced (STZ) diabetic…”
Get full text

Renal neuronal nitric oxide synthase protein expression as a marker of renal injury by Szabo, Attila J., Wagner, Laszlo, Erdely, Aaron, Lau, Kim, Baylis, Chris

“…Renal neuronal nitric oxide synthase protein expression as a marker of renal injury. Animal studies suggest that nitric oxide deficiency occurs in the remnant…”
Get full text

Oncological Screening of Kidney Transplant Patients: The Role of Ultrasound Examination by Kiss, Gergely, Korda, Dávid, Szabó, Gergő, Juhász, Réka, Wagner, László, Máthé, Zoltán, Doros, Attila, Végső, Gyula

“…Immunosuppressive therapy used after organ transplantation represents a considerable oncological risk. Abdominal ultrasound examinations play an essential role…”
Get full text

Case report: COVID-19 infection in a pregnant 33-year-old kidney transplant recipient by Supák, Dorina, Mészáros, Balázs, Nagy, Márta, Gáspár, Dániel, Wagner, László J., Kukor, Zoltán, Valent, Sándor

“…Patients facing severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infections with comorbidities, especially patients whose immune system is weakened…”
Get full text

3105 Tocilizumab for treatment of antibody mediated rejection in kidney transplant patients by Szabó, Eszter, Marton, Adrienn, Remport, Adam, Török, Szilárd, Patonai, Attila, Piros, László, Fintha, Attila, Szijártó, Attila, Wagner, Laszlo, Cseprekal, Orsolya

Get full text

Genetic analysis and functional characterization of novel mutations in a series of patients with atypical hemolytic uremic syndrome by Szarvas, Nóra, Szilágyi, Ágnes, Csuka, Dorottya, Takács, Beáta, Rusai, Krisztina, Müller, Thomas, Arbeiter, Klaus, Réti, Marienn, Haris, Ágnes, Wagner, László, Török, Szilárd, Kelen, Kata, Szabó, Attila J., Reusz, György S., Morgan, B. Paul, Prohászka, Zoltán

“…•30 aHUS patients and their family members were included in this study.•We identified 27 (12 novel) potentially disease-causing mutations in the genes CFH,…”
Get full text

MO1019: Sigma-1 Receptor Agonists are Protective in a Rat Model of Kidney Transplantation by Lakat, Tamas, Roland Toth, Akos, Hodrea, Judit, Wagner, Laszlo, Szabo, Attila, Fekete, Andrea, Hosszu, Adam

Get full text

NPHS2 homozygous p.R229Q variant: potential modifier instead of causal effect in focal segmental glomerulosclerosis by Kerti, Andrea, Csohány, Rózsa, Wagner, László, Jávorszky, Eszter, Maka, Erika, Tory, Kálmán

“…Background The pathogenicity of the NPHS2 homozygous p.R229Q variant in steroid-resistant nephrotic syndrome (SRNS) is doubtful. While it has been reported in…”
Get full text

Low-Dose vs Standard-Dose Valganciclovir for Cytomegalovirus Prophylaxis After Kidney Transplantation: A Single-Center Retrospective Analysis by Farkas, Katalin, Varga, Marina, Dinnyes, Izabella, Rem, Lili, Telkes, Gabor, Wagner, Laszlo, Remport, Adam, Piros, Laszlo, Szijarto, Attila, Huszty, Gergely

“…Prophylactic administration of valganciclovir (VG) is an accepted method for the prevention of cytomegalovirus (CMV) infection after kidney transplantation…”
Get full text

MO282: Sigma-1 Receptor Agonists are Protective in Renal Ischemia/Reperfusion Injury by Roland Toth, Akos, Lakat, Tamas, Hodrea, Judit, Balogh, Dora B, Vannay, Adam, Wagner, Laszlo, Szabo, Attila, Fekete, Andrea, Hosszu, Adam

Get full text