Search Results - "WAGGONER, Alan"

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    Fluoromodules Consisting of a Promiscuous RNA Aptamer and Red or Blue Fluorogenic Cyanine Dyes: Selection, Characterization, and Bioimaging by Tan, Xiaohong, Constantin, Tudor P, Sloane, Kelly L, Waggoner, Alan S, Bruchez, Marcel P, Armitage, Bruce A

    Published in Journal of the American Chemical Society (05-07-2017)
    “…An RNA aptamer selected for binding to the fluorogenic cyanine dye, dimethylindole red (DIR), also binds and activates another cyanine, oxazole thiazole blue…”
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    Malachite Green Mediates Homodimerization of Antibody VL Domains to Form a Fluorescent Ternary Complex with Singular Symmetric Interfaces by Szent-Gyorgyi, Chris, Stanfield, Robyn L., Andreko, Susan, Dempsey, Alison, Ahmed, Mushtaq, Capek, Sarah, Waggoner, Alan S., Wilson, Ian A., Bruchez, Marcel P.

    Published in Journal of molecular biology (15-11-2013)
    “…We report that a symmetric small-molecule ligand mediates the assembly of antibody light chain variable domains (VLs) into a correspondent symmetric ternary…”
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    Fluorescence imaging of tumors in vivo by Ballou, Byron, Ernst, Lauren A, Waggoner, Alan S

    Published in Current medicinal chemistry (01-01-2005)
    “…We review recent progress in tumor imaging in vivo using fluorescent tags, highlight the problems of fluorescence imaging in small animals, discuss recent…”
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    Twisted Cyanines: A Non-Planar Fluorogenic Dye with Superior Photostability and its Use in a Protein-Based Fluoromodule by Shank, Nathaniel I, Pham, Ha H, Waggoner, Alan S, Armitage, Bruce A

    Published in Journal of the American Chemical Society (09-01-2013)
    “…The cyanine dye thiazole orange (TO) is a well-known fluorogenic stain for DNA and RNA, but this property precludes its use as an intracellular fluorescent…”
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    Structural basis for activation of fluorogenic dyes by an RNA aptamer lacking a G-quadruplex motif by Shelke, Sandip A., Shao, Yaming, Laski, Artur, Koirala, Deepak, Weissman, Benjamin P., Fuller, James R., Tan, Xiaohong, Constantin, Tudor P., Waggoner, Alan S., Bruchez, Marcel P., Armitage, Bruce A., Piccirilli, Joseph A.

    Published in Nature communications (31-10-2018)
    “…The DIR2s RNA aptamer, a second-generation, in-vitro selected binder to dimethylindole red (DIR), activates the fluorescence of cyanine dyes, DIR and oxazole…”
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    Genetically Encoded pH Sensor for Tracking Surface Proteins through Endocytosis by Grover, Anmol, Schmidt, Brigitte F., Salter, Russell D., Watkins, Simon C., Waggoner, Alan S., Bruchez, Marcel P.

    Published in Angewandte Chemie International Edition (14-05-2012)
    “…Traffic cam: A tandem dye prepared from a FRET acceptor and a fluorogenic donor functions as a cell surface ratiometric pH indicator, which upon…”
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    Long-term Persistence and Spectral Blue Shifting of Quantum Dots in Vivo by Fitzpatrick, James A. J, Andreko, Susan K, Ernst, Lauren A, Waggoner, Alan S, Ballou, Byron, Bruchez, Marcel P

    Published in Nano letters (01-07-2009)
    “…Quantum dots are a powerful fluorophore family with desirable attributes for fluorescence imaging. They have been used in several animal models with direct…”
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    Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women by PETERSON, Linda R, HERRERO, Pilar, GROPLER, Robert J, SCHECHTMAN, Kenneth B, RACETTE, Susan B, WAGGONER, Alan D, KISRIEVA-WARE, Zulia, DENCE, Carmen, KLEIN, Samuel, MARSALA, Joann, MEYER, Timothy

    Published in Circulation (New York, N.Y.) (11-05-2004)
    “…Obesity is a risk factor for impaired cardiac performance, particularly in women. Animal studies suggest that alterations in myocardial fatty acid metabolism…”
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    Intracellular pH Measurements Using Perfluorocarbon Nanoemulsions by Patrick, Michael J, Janjic, Jelena M, Teng, Haibing, O’Hear, Meredith R, Brown, Cortlyn W, Stokum, Jesse A, Schmidt, Brigitte F, Ahrens, Eric T, Waggoner, Alan S

    Published in Journal of the American Chemical Society (11-12-2013)
    “…We report the synthesis and formulation of unique perfluorocarbon (PFC) nanoemulsions enabling intracellular pH measurements in living cells via fluorescent…”
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    Spectral Properties of Fluorogenic Thiophene‐derived Triarylmethane Dyes by Stensrud, Kenneth F., Zanotti, Kimberly J., Waggoner, Alan S., Armitage, Bruce A.

    Published in Photochemistry and photobiology (01-01-2019)
    “…Spectral properties and fluorogenic behaviors of five novel thiophene variants of malachite green (MG), termed MGTs, were determined. Appreciable changes as a…”
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    Fluoromodule-based reporter/probes designed for in vivo fluorescence imaging by Zhang, Ming, Chakraborty, Subhasish K, Sampath, Padma, Rojas, Juan J, Hou, Weizhou, Saurabh, Saumya, Thorne, Steve H, Bruchez, Marcel P, Waggoner, Alan S

    Published in The Journal of clinical investigation (01-10-2015)
    “…Optical imaging of whole, living animals has proven to be a powerful tool in multiple areas of preclinical research and has allowed noninvasive monitoring of…”
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    Synthesis of New Fluorogenic Cyanine Dyes and Incorporation into RNA Fluoromodules by Constantin, Tudor P, Silva, Gloria L, Robertson, Kelly L, Hamilton, Tamara P, Fague, Kaitlin, Waggoner, Alan S, Armitage, Bruce A

    Published in Organic letters (17-04-2008)
    “…A new fluorogenic cyanine dye was synthesized and found to have low fluorescence quantum yield in fluid solution and in the presence of double-stranded DNA but…”
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    Inhibiting clathrin-mediated endocytosis of the leucine-rich G protein-coupled receptor-5 diminishes cell fitness by Snyder, Joshua C., Rochelle, Lauren K., Ray, Caroline, Pack, Thomas F., Bock, Cheryl B., Lubkov, Veronica, Lyerly, H. Kim, Waggoner, Alan S., Barak, Larry S., Caron, Marc G.

    Published in The Journal of biological chemistry (28-04-2017)
    “…The leucine-rich G protein-coupled receptor-5 (LGR5) is expressed in adult tissue stem cells of many epithelia, and its overexpression is negatively correlated…”
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