Search Results - "WADA, Seiki"

Essential Role of p38 Mitogen-activated Protein Kinase in Cathepsin K Gene Expression during Osteoclastogenesis through Association of NFATc1 and PU.1 by Matsumoto, Masahito, Kogawa, Masakazu, Wada, Seiki, Takayanagi, Hiroshi, Tsujimoto, Masafumi, Katayama, Shigehiro, Hisatake, Koji, Nogi, Yasuhisa

“…The receptor activator of NF-κB ligand (RANKL) induces various osteoclast-specific marker genes during osteoclast differentiation mediated by…”
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Effects of IL-23 and IL-27 on osteoblasts and osteoclasts : inhibitory effects on osteoclast differentiation by KAMIYA, Sadahiro, NAKAMURA, Chika, FUKAWA, Takeshi, ONO, Katsuhiro, OHWAKI, Toshiyuki, YOSHIMOTO, Takayuki, WADA, Seiki

“…Interleukin (IL)-23 and IL-27 are IL-6/IL-12 family members that play a role in the regulation of T helper 1 cell differentiation. Cytokines are known to be…”
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Involvement of hepatocyte growth factor in the development of bone metastasis of a mouse mammary cancer cell line, BALB/c-MC by Ono, Katsuhiro, Kamiya, Sadahiro, Akatsu, Takuhiko, Nakamura, Chika, Li, Minqi, Amizuka, Norio, Matsumoto, Kunio, Nakamura, Toshikazu, Kugai, Nobuo, Wada, Seiki

“…Some cancers frequently affect the skeleton, and the bone microenvironment supports growth of certain cancer cells. After tumors metastasize to bone, they…”
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Caspase 8 and menin expressions are not correlated in human parathyroid tumors by Yu, Dong, Nagamura, Yuko, Shimazu, Satoko, Naito, Junko, Kaji, Hiroshi, Wada, Seiki, Honda, Munehiro, Xue, Lian, Tsukada, Toshihiko

“…Menin is lost by the sequential inactivation of both MEN1 alleles in subsets of non-hereditary endocrine tumors as well as those associated with multiple…”
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Therapeutic approaches for diabetic osteopahty by Wada, Seiki

“…Although the clinical manifestations of diabetic osteopahty are not fully elucidated, diabetes may affect bone remodeling by various mechanisms, including…”
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Antiadhesive Sites Present in the Fibronectin Type III-Like Repeats of Human Plasma Fibronectin by Miura, Shogo, Kamiya, Sadahiro, Saito, Yohei, Wada, Seiki, Hayashi, Ryo, Taira, Junichi, Kodama, Hiroaki, Yajima, Hirofumi, Ueki, Masaaki, Fukai, Fumio

“…We have found that fibronectin (FN) has a functional cryptic site opposing cell adhesion to extracellular matrix (ECM): a synthetic FN peptide derived from the…”
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Present development of new drugs for osteoporosis by Wada, Seiki

“…Bisphosphonates are widely used, though gastrointestinal tolerance is a problem on daily administration. Alendronate 35 mg administered once weekly is as…”
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A case of primary mucoepidermoid carcinoma of the thyroid: molecular evidence of its origin by Minagawa, Akinobu, Iitaka, Makoto, Suzuki, Miho, Yasuda, Shigemitsu, Kameyama, Kaori, Shimada, Shio, Kitahama, Shinji, Wada, Seiki, Katayama, Shigehiro

“…Summary Primary mucoepidermoid carcinoma (MEC) of the thyroid is very rare, and its origin has not been fully determined. We report a case of MEC, the origin…”
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Biochemical markers of bone turnover. New aspect. Bone metabolic markers available in daily practice by Wada, Seiki, Fukawa, Takeshi, Kamiya, Sadahiro

“…Changes of bone remodeling markers reflect bone growth and bone turnover. Information on bone metabolism can be attained by blood and urine laboratory tests…”
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Osteocalcin and bone by Wada, Seiki, Fukawa, Takeshi, Kamiya, Sadahiro

“…Osteocalcin (OC) is a product of osteoblasts and accumulated in the extracellular matrix of bone. It has been recognized that serum OC is a marker of…”
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Diabetic osteopahty and vitamin K by Yasuda, Shigemitsu, Wada, Seiki

“…Diabetes mellitus is considered as a risk factor for fractures, and there are some reports showing that metabolic effects of poor glycemic control resulted in…”
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Bone and bone related biochemical examinations. Bone and collagen related metabolites. Osteocalcin (OC) by Wada, Seiki, Kamiya, Sadahiro

“…Osteocalcin is produced by mature osteoblasts and primarily deposited in the extracellular matrix of skeletal tissue. It has been shown that serum osteocalcin…”
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Osteoporosis and alcohol intake by Kogawa, Masakazu, Wada, Seiki

“…Current understanding suggests that moderate quantities of alcohol use may have beneficial effects on bone mineral density, irrespective of age and sex, and…”
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Molecular biology in regulation of kidney functions: Calcitonin by Wada, Seiki, Yasuda, Shigemitsu

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Bone quality changes in diabetes by Wada, Seiki, Kamiya, Sadahiro, Fukawa, Takeshi

“…Diabetes-related bone fragility has recently drawn many researchers' attention. Diabetes would affect bone remodeling by various mechanisms, including…”
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Regulation of calcification by bisphosphonates by Ono, Katsuhiro, Wada, Seiki

“…Etidronate, an analogue of first generation of bisphosphonates, has inhibitory actions on mineralization and hydroxyapatite crystal formation, which is…”
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Efficacy, Safety, and Tolerability of Oral Semaglutide Versus Placebo Added to Insulin With or Without Metformin in Patients With Type 2 Diabetes: The PIONEER 8 Trial by Zinman, Bernard, Aroda, Vanita R, Buse, John B, Cariou, Bertrand, Harris, Stewart B, Hoff, Søren Tetens, Pedersen, Karen Boje, Tarp-Johansen, Mads Jeppe, Araki, Eiichi

“…To investigate the efficacy, safety, and tolerability of oral semaglutide added to insulin with or without metformin. Patients with type 2 diabetes…”
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Newly developed drugs for osteoporosis in overseas and their future roles for the therapy by Wada, Seiki, Fukawa, Takeshi, Kamiya, Sadahiro

“…Bisphosphonates are widely used, though gastrointestinal tolerance is a problem on daily administration. Intermittent regimen, from once weekly to once yearly,…”
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New bone density conservation agents for osteoporosis under research and development: Anti-RANKL antibody by Wada, Seiki, Fukawa, Takeshi, Kamiya, Sadahiro

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New bone density conservation agents for osteoporosis under research and development: Zoledronate by Wada, Seiki, Fukawa, Takeshi, Kamiya, Sadahiro

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