Search Results - "Wąsik, Agnieszka"

Advantages and Limitations of Animal Schizophrenia Models by Białoń, Magdalena, Wąsik, Agnieszka

“…Mental illness modeling is still a major challenge for scientists. Animal models of schizophrenia are essential to gain a better understanding of the disease…”
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The mechanism of neuroprotective action of natural compounds by Wąsik, Agnieszka, Antkiewicz-Michaluk, Lucyna

“…Disturbance of cerebral redox homeostasis is the primary cause of human neurodegenerative disorders, such as Parkinson's disease or Alzheimer's disease. Well…”
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Comparison of the effects of 1MeTIQ and olanzapine on performance in the elevated plus maze test and monoamine metabolism in the brain after ketamine treatment by Wąsik, Agnieszka, Białoń, Magdalena, Żarnowska, Marcelina, Antkiewicz-Michaluk, Lucyna

“…Anxiety is a common symptom of schizophrenia. Ketamine, which acts as a noncompetitive antagonist of glutamatergic NMDA receptors by binding to the…”
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Acute and Chronic Exposure to Linagliptin, a Selective Inhibitor of Dipeptidyl Peptidase-4 (DPP-4), Has an Effect on Dopamine, Serotonin and Noradrenaline Level in the Striatum and Hippocampus of Rats by Łupina, Małgorzata, Wąsik, Agnieszka, Baranowska-Bosiacka, Irena, Tarnowski, Maciej, Słowik, Tymoteusz, Listos, Piotr, Kotlińska, Jolanta, Kosik-Bogacka, Danuta, Gutowska, Izabela, Listos, Joanna

“…Linagliptin is a selective dipeptidyl peptidase-4 (DPP-4) inhibitor that indirectly elevates the glucagon-like peptide-1 (GLP-1) level. The aim of the present…”
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Fluoride Affects Dopamine Metabolism and Causes Changes in the Expression of Dopamine Receptors (D1R and D2R) in Chosen Brain Structures of Morphine-Dependent Rats by Kupnicka, Patrycja, Listos, Joanna, Tarnowski, Maciej, Kolasa-Wołosiuk, Agnieszka, Wąsik, Agnieszka, Łukomska, Agnieszka, Barczak, Katarzyna, Gutowska, Izabela, Chlubek, Dariusz, Baranowska-Bosiacka, Irena

“…Disturbances caused by excess or shortages of certain elements can affect the cerebral reward system and may therefore modulate the processes associated with…”
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Changes in Monoaminergic Neurotransmission in an Animal Model of Osteoarthritis: The Role of Endocannabinoid Signaling by Mlost, Jakub, Wąsik, Agnieszka, Michaluk, Jerzy Tadeusz, Antkiewicz-Michaluk, Lucyna, Starowicz, Katarzyna

“…Chronic pain is a main symptom of osteoarthritis (OA). Moreover, a high percentage of OA patients suffer from mental health problems. The endocannabinoid (EC)…”
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Salsolinol, an Endogenous Compound Triggers a Two-Phase Opposing Action in the Central Nervous System by Możdżeń, Edyta, Kajta, Małgorzata, Wąsik, Agnieszka, Lenda, Tomasz, Antkiewicz-Michaluk, Lucyna

“…Salsolinol (1-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline), an endogenous compound present in the brain, was suspected of participation in the…”
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Negative Allosteric Modulators of mGlu7 Receptor as Putative Antipsychotic Drugs by Cieślik, Paulina, Woźniak, Monika, Kaczorowska, Katarzyna, Brański, Piotr, Burnat, Grzegorz, Chocyk, Agnieszka, Bobula, Bartosz, Gruca, Piotr, Litwa, Ewa, Pałucha-Poniewiera, Agnieszka, Wąsik, Agnieszka, Pilc, Andrzej, Wierońska, Joanna

“…The data concerning antipsychotic-like activity of negative allosteric modulators/antagonists of mGlu7 receptors are limited. The only available ligands for…”
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1-Benzyl-1,2,3,4-Tetrahydroisoquinoline, an Endogenous Parkinsonism-Inducing Toxin, Strongly Potentiates MAO-Dependent Dopamine Oxidation and Impairs Dopamine Release: Ex vivo and In vivo Neurochemical Studies by Wąsik, Agnieszka, Romańska, Irena, Antkiewicz-Michaluk, Lucyna

“…1-Benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ), an endogenous neurotoxin, is known to cause a parkinsonism-like syndrome in rodents and primates. In this…”
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Pro-cognitive effect of 1MeTIQ on recognition memory in the ketamine model of schizophrenia in rats: the behavioural and neurochemical effects by Bialon, Magdalena, Zarnowska, Marcelina, Antkiewicz-Michaluk, Lucyna, Wasik, Agnieszka

“…Rationale Schizophrenia is a mental illness which is characterised by positive and negative symptoms and by cognitive impairments. While the major prevailing…”
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Role of endocannabinoid system in dopamine signalling within the reward circuits affected by chronic pain by Mlost, Jakub, Wąsik, Agnieszka, Starowicz, Katarzyna

“…[Display omitted] The association between chronic pain, depression and anxiety has gained particular attention due to high rates of comorbidity. Recent data…”
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Network analysis of monoamines involved in anxiety-like behavior in a rat model of osteoarthritis by Mlost, Jakub, Białoń, Magdalena, Kędziora, Marta, Wąsik, Agnieszka, Michalec, Żaneta, Starowicz, Katarzyna

“…Chronic pain is a major health problem that affects a significant number of patients, resulting in personal suffering and substantial health care costs. One of…”
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Effect of combined treatment with aripiprazole and antidepressants on the MK-801-induced deficits in recognition memory in novel recognition test and on the release of monoamines in the rat frontal cortex by Hereta, Marta, Kamińska, Kinga, Białoń, Magdalena, Wąsik, Agnieszka, Lorenc-Koci, Elżbieta, Rogóż, Zofia

“…•Antidepressants increased the aripiprazole action in novel object recognition test.•Positive interaction in recognition memory test involves the 5HT1A and DA1…”
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The Effect of Glutathione Deficit During Early Postnatal Brain Development on the Prepulse Inhibition and Monoamine Levels in Brain Structures of Adult Sprague–Dawley Rats by Rogóż, Zofia, Lech, Marta A., Chamera, Katarzyna, Wąsik, Agnieszka

“…Recent studies suggest that impaired glutathione synthesis and distorted dopaminergic transmission are important factors in the pathophysiology of…”
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The Impact of the Combined Administration of 1MeTIQ and MK-801 on Cell Viability, Oxidative Stress Markers, and Glutamate Release in the Rat Hippocampus by Wąsik, Agnieszka, Białoń, Magdalena, Jantas, Danuta, Żarnowska, Marcelina

“…MK-801, as an N-methyl-D-aspartate (NMDA) receptor inhibitor, causes elevation in glutamate release, which may lead to an increase in excitotoxicity, oxidative…”
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Antidepressant-like Effect of Tetrahydroisoquinoline Amines in the Animal Model of Depressive Disorder Induced by Repeated Administration of a Low Dose of Reserpine: Behavioral and Neurochemical Studies in the Rat by Antkiewicz-Michaluk, Lucyna, Wąsik, Agnieszka, Możdżeń, Edyta, Romańska, Irena, Michaluk, Jerzy

“…Animal models are widely used to study antidepressant-like effect in rodents. However, it should be mentioned that pharmacological models do not always take…”
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1-Methyl-1,2,3,4-Tetrahydroisoquinoline, an Endogenous Amine with Unexpected Mechanism of Action: New Vistas of Therapeutic Application by Antkiewicz-Michaluk, Lucyna, Wąsik, Agnieszka, Michaluk, Jerzy

“…This review outlines the effects of 1,2,3,4-tetrahydroisoquinoline (TIQ) and its derivative, 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ), endogenous…”
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Multiple Administration of Endogenous Amines TIQ and 1MeTIQ Protects Against a 6-OHDA-Induced Essential Fall of Dopamine Release in the Rat Striatum: In Vivo Microdialysis Study by Wąsik, Agnieszka, Romańska, Irena, Zelek-Molik, Agnieszka, Antkiewicz-Michaluk, Lucyna

“…Parkinson’s disease (PD) represents one of the neurodegenerative disorders which are caused by degeneration of dopaminergic neurons in the nigrostriatal…”
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Combined treatment with aripiprazole and antidepressants reversed some MK-801-induced schizophrenia-like symptoms in mice by Rogóż, Zofia, Wąsik, Agnieszka, Lorenc-Koci, Elzbieta

“…Atypical antipsychotic drugs have some efficacy in alleviating the negative and some cognitive symptoms of schizophrenia but those effects are small and…”
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Antidepressant-Like Effect of the Endogenous Neuroprotective Amine, 1MeTIQ in Clonidine-Induced Depression: Behavioral and Neurochemical Studies in Rats by Antkiewicz-Michaluk, Lucyna, Romańska, Irena, Wąsik, Agnieszka, Michaluk, Jerzy

“…Biogenic amines such as norepinephrine, dopamine, and serotonin play a well-described role in the treatment of mood disorders especially depression. Animal…”
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