Search Results - "Würstle, Silvia"

Automated, flow-based chemiluminescence microarray immunoassay for the rapid multiplex detection of IgG antibodies to SARS-CoV-2 in human serum and plasma (CoVRapid CL-MIA) by Klüpfel, Julia, Koros, Rosa Carolina, Dehne, Kerstin, Ungerer, Martin, Würstle, Silvia, Mautner, Josef, Feuerherd, Martin, Protzer, Ulrike, Hayden, Oliver, Elsner, Martin, Seidel, Michael

“…In the face of the COVID-19 pandemic, the need for rapid serological tests that allow multiplexing emerged, as antibody seropositivity can instruct about…”
Get full text

Salphage: salvage bacteriophage therapy for a recalcitrant Klebsiella pneumoniae prosthetic shoulder infection - a case report by Doub, James B, Shishido, Akira, Srikumaran, Uma, Haskoor, John, Tran-Nguyen, Phuong, Lee, Myounghee, Würstle, Silvia, Lee, Alina, Kortright, Kaitlyn, Chan, Benjamin K

Get full text

Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University by Würstle, Silvia, Lee, Alina, Kortright, Kaitlyn E., Winzig, Franziska, An, William, Stanley, Gail L., Rajagopalan, Govindarajan, Harris, Zach, Sun, Ying, Hu, Buqu, Blazanin, Michael, Hajfathalian, Maryam, Bollyky, Paul L., Turner, Paul E., Koff, Jonathan L., Chan, Benjamin K.

“…Bacteriophage therapy is one potential strategy to treat antimicrobial resistant or persistent bacterial infections, and the year 2021 marked the centennial of…”
Get full text

Salphage: Salvage Bacteriophage Therapy for Recalcitrant MRSA Prosthetic Joint Infection by Doub, James B, Ng, Vincent Y, Lee, Myounghee, Chi, Andrew, Lee, Alina, Würstle, Silvia, Chan, Benjamin

“…Prosthetic joint infections are a devastating complication of joint replacement surgery. Consequently, novel therapeutics are needed to thwart the significant…”
Get full text

Self-sampling versus health care professional-guided swab collection for SARS-CoV-2 testing by Würstle, Silvia, Spinner, Christoph D., Voit, Florian, Hoffmann, Dieter, Hering, Svenja, Weidlich, Simon, Schneider, Jochen, Zink, Alexander, Treiber, Matthias, Iakoubov, Roman, Schmid, Roland M., Protzer, Ulrike, Erber, Johanna

“…Purpose To evaluate the diagnostic reliability and practicability of self-collected oropharyngeal swab samples for the detection of SARS-CoV-2 infection as…”
Get full text

Cytosolic Hsp70 as a biomarker to predict clinical outcome in patients with glioblastoma by Lämmer, Friederike, Delbridge, Claire, Würstle, Silvia, Neff, Frauke, Meyer, Bernhard, Schlegel, Jürgen, Kessel, Kerstin A, Schmid, Thomas E, Schilling, Daniela, Combs, Stephanie E

“…The major stress-inducible heat shock protein 70 (Hsp70) is induced after different stress stimuli. In tumors, elevated intracellular Hsp70 levels were…”
Get full text

Novel antimicrobial coatings based on polylactide for plastic biliary stents to prevent post-endoscopic retrograde cholangiography cholangitis by Obermeier, Andreas, Würstle, Silvia, Tübel, Jutta, Stolte, Philipp, Feihl, Susanne, Lipovcic, Nikolina, Lanzinger, Sonja, Mühlhofer, Heinrich, Weber, Andreas, Schmid, Roland M, Burgkart, Rainer, Schneider, Jochen

“…Abstract Background Cholangitis is a common complication after endoscopic retrograde cholangiography (ERC). Objectives To evaluate antimicrobial coatings for…”
Get full text

Correction: Cytosolic Hsp70 as a biomarker to predict clinical outcome in patients with glioblastoma by Lämmer, Friederike, Delbridge, Claire, Würstle, Silvia, Neff, Frauke, Meyer, Bernhard, Schlegel, Jürgen, Kessel, Kerstin A, Schmid, Thomas E, Schilling, Daniela, Combs, Stephanie E

“…[This corrects the article DOI: 10.1371/journal.pone.0221502.]…”
Get full text

Practical Assessment of an Interdisciplinary Bacteriophage Delivery Pipeline for Personalized Therapy of Gram-Negative Bacterial Infections by Würstle, Silvia, Stender, Jana, Hammerl, Jens André, Vogele, Kilian, Rothe, Kathrin, Willy, Christian, Bugert, Joachim Jakob

“…Despite numerous advances in personalized phage therapy, smooth logistics are challenging, particularly for multidrug-resistant Gram-negative bacterial…”
Get full text

Phage Therapy in Germany-Update 2023 by Willy, Christian, Bugert, Joachim J, Classen, Annika Y, Deng, Li, Düchting, Anja, Gross, Justus, Hammerl, Jens A, Korf, Imke H E, Kühn, Christian, Lieberknecht-Jouy, Simone, Rohde, Christine, Rupp, Markus, Vehreschild, Maria J G T, Vogele, Kilian, Wienecke, Sarah, Witzenrath, Martin, Würstle, Silvia, Ziehr, Holger, Moelling, Karin, Broecker, Felix

“…Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview of the current…”
Get full text

Evaluation of a Virtual Reality-Based Open Educational Resource Software by Würstle, Silvia, Spanke, Lisa-Marie, Mehlhase, Niklas, Stanley, Gail, Koff, Jonathan, Dimitriadis, Stavros, König, Sarah, Hann, Alexander

“…Virtual reality (VR) teaching methods have potential to support medical students acquire increasing amounts of knowledge. EVENT (Easy VR EducatioN Tool) is an…”
Get full text

SARS-CoV-2 serology increases diagnostic accuracy in CT-suspected, PCR-negative COVID-19 patients during pandemic by Schneider, Jochen, Mijočević, Hrvoje, Ulm, Kurt, Ulm, Bernhard, Weidlich, Simon, Würstle, Silvia, Rothe, Kathrin, Treiber, Matthias, Iakoubov, Roman, Mayr, Ulrich, Lahmer, Tobias, Rasch, Sebastian, Herner, Alexander, Burian, Egon, Lohöfer, Fabian, Braren, Rickmer, Makowski, Marcus R, Schmid, Roland M, Protzer, Ulrike, Spinner, Christoph, Geisler, Fabian

“…In the absence of PCR detection of SARS-CoV-2 RNA, accurate diagnosis of COVID-19 is challenging. Low-dose computed tomography (CT) detects pulmonary…”
Get full text

Treatment of intestinal tuberculosis with small bowel perforation: a case report by Sasse, Daniel, Spinner, Christoph D, Rothe, Kathrin, Schneider, Jochen, Gaa, Jochen, Würstle, Silvia

“…Diagnosis of intestinal tuberculosis poses a dilemma to physicians due to nonspecific symptoms like abdominal pain, fever, nausea, and a change in bowel habit…”
Get full text

A Telemedicine-Guided Self-Collection Approach for PCR-Based SARS-CoV-2 Testing: Comparative Study by Würstle, Silvia, Erber, Johanna, Hanselmann, Michael, Hoffmann, Dieter, Werfel, Stanislas, Hering, Svenja, Weidlich, Simon, Schneider, Jochen, Franke, Ralf, Maier, Michael, Henkel, Andreas G, Schmid, Roland M, Protzer, Ulrike, Laxy, Michael, Spinner, Christoph D

“…Large-scale, polymerase chain reaction (PCR)-based SARS-CoV-2 testing is expensive, resource intensive, and time consuming. A self-collection approach is a…”
Get full text

A Novel Zinc (II) Porphyrin Is Synergistic with PEV2 Bacteriophage against Pseudomonas aeruginosa Infections by Geyer, Jessica, Krupa, Kristen A, Harris, Zachary M, Sun, Ying, Sharma, Lokesh, Würstle, Silvia, Hu, Buqu, Stanley, Gail, Rajagopalan, Govindarajan, Pellot, Erin, Koff, Jonathan L, Robinson, Jayne B

“…(PsA) is an opportunistic bacterial pathogen that causes life-threatening infections in individuals with compromised immune systems and exacerbates health…”
Get full text

A Novel Machine Learning-Based Point-Score Model as a Non-Invasive Decision-Making Tool for Identifying Infected Ascites in Patients with Hydropic Decompensated Liver Cirrhosis: A Retrospective Multicentre Study by Würstle, Silvia, Hapfelmeier, Alexander, Karapetyan, Siranush, Studen, Fabian, Isaakidou, Andriana, Schneider, Tillman, Schmid, Roland M, von Delius, Stefan, Gundling, Felix, Triebelhorn, Julian, Burgkart, Rainer, Obermeier, Andreas, Mayr, Ulrich, Heller, Stephan, Rasch, Sebastian, Lahmer, Tobias, Geisler, Fabian, Chan, Benjamin, Turner, Paul E, Rothe, Kathrin, Spinner, Christoph D, Schneider, Jochen

“…This study is aimed at assessing the distinctive features of patients with infected ascites and liver cirrhosis and developing a scoring system to allow for…”
Get full text

Differentiation of Spontaneous Bacterial Peritonitis from Secondary Peritonitis in Patients with Liver Cirrhosis: Retrospective Multicentre Study by Würstle, Silvia, Hapfelmeier, Alexander, Karapetyan, Siranush, Studen, Fabian, Isaakidou, Andriana, Schneider, Tillman, Schmid, Roland M, von Delius, Stefan, Gundling, Felix, Burgkart, Rainer, Obermeier, Andreas, Mayr, Ulrich, Ringelhan, Marc, Rasch, Sebastian, Lahmer, Tobias, Geisler, Fabian, Turner, Paul E, Chan, Benjamin K, Spinner, Christoph D, Schneider, Jochen

“…Ascitic fluid infection is a serious complication of liver cirrhosis. The distinction between the more common spontaneous bacterial peritonitis (SBP) and the…”
Get full text

LINAS‐Score: prognostic model for mortality assessment in patients with cirrhotic liver and infected ascites by Würstle, Silvia, Schneider, Tillman, Karapetyan, Siranush, Hapfelmeier, Alexander, Isaakidou, Andriana, Studen, Fabian, Schmid, Roland M., Delius, Stephan, Rothe, Kathrin, Burgkart, Rainer, Obermeier, Andreas, Triebelhorn, Julian, Erber, Johanna, Voit, Florian, Geisler, Fabian, Spinner, Christoph D., Schneider, Jochen, Wagner, Laura

“…Background and Aim Patients with liver cirrhosis often face a grave threat from infected ascites (IA). However, a well‐established prognostic model for this…”
Get full text

Changes in pathogen spectrum and antimicrobial resistance development in the time‐course of acute necrotizing pancreatitis by Würstle, Silvia, Hapfelmeier, Alexander, Wöhrle, Caroline, Dichtl, Karl, Lahmer, Tobias, Rasch, Sebastian, Huber, Wolfgang, Weber, Andreas, Algül, Hana, Spinner, Christoph, Pichler, Matthias, Schmid, Roland M, Mayerle, Julia, Schneider, Jochen

“…Background and Aim In contrast to the first peak of multi‐organ failure in acute pancreatitis, the second peak is mostly triggered by septic complications. Our…”
Get full text

Inhaled Bacteriophage Therapy for Multi-Drug Resistant Achromobacter by Winzig, Franziska, Gandhi, Shiv, Lee, Alina, Würstle, Silvia, Stanley, Gail L, Capuano, Isabella, Neuringer, Isabel, Koff, Jonathan L, Turner, Paul E, Chan, Benjamin K

“…The rise of antimicrobial resistant (AMR) bacteria is a global public health threat. AMR bacteria pose a challenging clinical problem, particularly for those…”
Get full text