Search Results - "Würbel, Hanno"
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1
Reproducibility of animal research in light of biological variation
Published in Nature reviews. Neuroscience (01-07-2020)“…Context-dependent biological variation presents a unique challenge to the reproducibility of results in experimental animal research, because organisms’…”
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2
Facial Indicators of Positive Emotions in Rats
Published in PloS one (30-11-2016)“…Until recently, research in animal welfare science has mainly focused on negative experiences like pain and suffering, often neglecting the importance of…”
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The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
Published in The Journal of physiology (01-09-2020)“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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4
Differences in facial expressions during positive anticipation and frustration in dogs awaiting a reward
Published in Scientific reports (17-12-2019)“…Facial expressions are considered sensitive indicators of emotional states in humans and many animals. Identifying facial indicators of emotion is a major…”
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5
The standardization fallacy
Published in Nature methods (01-01-2021)“…“We demand rigidly defined areas of doubt and uncertainty!” —D. Adams…”
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The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Published in Experimental physiology (01-09-2020)“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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7
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Published in PLoS biology (14-07-2020)“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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8
Effects of weaning age and housing conditions on phenotypic differences in mice
Published in Scientific reports (15-07-2020)“…Poor reproducibility is considered a serious problem in laboratory animal research, with important scientific, economic, and ethical implications. One possible…”
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9
Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0
Published in PLoS biology (14-07-2020)“…Improving the reproducibility of biomedical research is a major challenge. Transparent and accurate reporting is vital to this process; it allows readers to…”
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10
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Published in BMC veterinary research (14-07-2020)“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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11
The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research
Published in Journal of cerebral blood flow and metabolism (01-09-2020)“…Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in…”
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12
Reproducibility and replicability of rodent phenotyping in preclinical studies
Published in Neuroscience and biobehavioral reviews (01-04-2018)“…•Many published scientific discoveries fail to replicate.•The field of mouse behavioral phenotyping was one of the first to raise this concern.•Replicability…”
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13
Play like me: Similarity in playfulness promotes social play
Published in PloS one (24-10-2019)“…Social play is associated with the experience of positive emotions in higher vertebrates and may be used as a measure of animal welfare. Altering motivation to…”
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14
Effects of Cage Enrichment on Behavior, Welfare and Outcome Variability in Female Mice
Published in Frontiers in behavioral neuroscience (26-10-2018)“…The manner in which laboratory rodents are housed is driven by economics (minimal use of space and resources), ergonomics (ease of handling and visibility of…”
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15
The impact of cage dividers on mouse aggression, dominance and hormone levels
Published in PloS one (07-02-2024)“…Home cage aggression in group-housed male mice is a major welfare concern and may compromise animal research. Conventional cages prevent flight or retreat from…”
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16
Systematic variation improves reproducibility of animal experiments
Published in Nature methods (01-03-2010)Get full text
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17
Authorization of Animal Experiments Is Based on Confidence Rather than Evidence of Scientific Rigor
Published in PLoS biology (02-12-2016)“…Accumulating evidence indicates high risk of bias in preclinical animal research, questioning the scientific validity and reproducibility of published research…”
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18
Handling method affects measures of anxiety, but not chronic stress in mice
Published in Scientific reports (03-12-2022)“…Studies in mice have shown that less aversive handling methods (e.g. tunnel or cup handling) can reduce behavioural measures of anxiety in comparison to…”
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19
Development of the "Highly Sensitive Dog" questionnaire to evaluate the personality dimension "Sensory Processing Sensitivity" in dogs
Published in PloS one (16-05-2017)“…In humans, the personality dimension 'sensory processing sensitivity (SPS)', also referred to as "high sensitivity", involves deeper processing of sensory…”
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Systematic assessment of the replicability and generalizability of preclinical findings: Impact of protocol harmonization across laboratory sites
Published in PLoS biology (23-11-2022)“…The influence of protocol standardization between laboratories on their replicability of preclinical results has not been addressed in a systematic way. While…”
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