Search Results - "Wójcikowski, J."
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Effects of imipramine on cytokines panel in the rats serum during the drug treatment and discontinuation
Published in Neurochemistry international (01-02-2018)“…Time dependent sensitization (TDS) - phenomenon described originally by Chiodo and Antelman (1980) in context of dopamine receptors, refers to cascade of…”
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Potent inhibition of CYP1A2 and CYP2D6 by the novel antipsychotic drug asenapine in human liver
Published in European neuropsychopharmacology (01-10-2016)Get full text
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Involvement of cytochrome P450 2D in the formation of serotonin in the brain: in vivo and in vitro study
Published in European neuropsychopharmacology (01-10-2016)Get full text
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P.3.c.008 Concentration-dependent contribution of human cytochrome P450 isoenzymes to the metabolism of levomepromazine
Published in European neuropsychopharmacology (01-10-2013)Get full text
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The effect of antidepressant treatment on the activity of liver cytochrome P450 (CYP) during chronic mild stress (CMS)
Published in European neuropsychopharmacology (01-10-2016)Get full text
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P.1.c.010 Cytochrome P450 mediates the synthesis of monoaminergic neurotransmitters in the brain
Published in European neuropsychopharmacology (2011)Get full text
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P.3.c.005 - Potent inhibition of CYP1A2 and CYP2D6 by the novel antipsychotic drug asenapine in human liver
Published in European neuropsychopharmacology (01-10-2016)Get full text
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The effect of tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs) and newer antidepressant drugs on the activity and level of rat CYP3A
Published in European neuropsychopharmacology (01-04-2006)“…The aim of the present study was to investigate the influence of tricyclic antidepressants (TADs: imipramine, amitriptyline, clomipramine, and desipramine),…”
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Clozapine and levomepromazine induce the cytochrome P450 isoenzyme CYP3A4, but not CYP1A1/2, in human hepatocytes
Published in European neuropsychopharmacology (01-10-2017)Get full text
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P.3.c.012 - Clozapine and levomepromazine induce the cytochrome P450 isoenzyme CYP3A4, but not CYP1A1/2, in human hepatocytes
Published in European neuropsychopharmacology (01-10-2017)Get full text
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P.1.g.082 - Involvement of cytochrome P450 2D in the formation of serotonin in the brain: in vivo and in vitro study
Published in European neuropsychopharmacology (01-10-2016)Get full text
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The Role of Lysosomes in the Cellular Distribution of Thioridazine and Potential Drug Interactions
Published in Toxicology and applied pharmacology (15-07-1999)“…The purpose of the present study was to investigate the contribution of lysosomal trapping to the total tissue uptake of thioridazine and to potential drug…”
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Intracellular distribution of psychotropic drugs in the grey and white matter of the brain: the role of lysosomal trapping
Published in British journal of pharmacology (01-10-2001)“…Since the brain is not a homogenous organ (i.e. the phospholipid pattern and density of lysosomes may vary in its different regions), in the present study we…”
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Inhibition of rat liver CYP2D in vitro and after 1-day and long-term exposure to neuroleptics in vivo–possible involvement of different mechanisms
Published in European neuropsychopharmacology (2005)“…The aim of the present study was to investigate the influence of classic and atypical neuroleptics on the activity of rat CYP2D measured as a rate of…”
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The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes
Published in European neuropsychopharmacology (01-05-2004)“…Identification of cytochrome P-450 isoenzymes (CYPs) involved in perazine 5-sulphoxidation and N-demethylation was carried out using human liver microsomes and…”
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Inhibition and possible induction of rat CYP2D after short- and long-term treatment with antidepressants
Published in Journal of pharmacy and pharmacology (01-11-2002)“…The aim of this study was to investigate the influence of tricyclic antidepressants (imipramine, amitriptyline, clomipramine, desipramine), selective serotonin…”
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Pharmacokinetics and metabolism of thioridazine during co‐administration of tricyclic antidepressants
Published in British journal of pharmacology (01-09-2000)“…Because of serious side‐effects of thioridazine and tricyclic antidepressants (cardiotoxicity), a possible influence of imipramine and amitriptyline on the…”
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Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants
Published in European neuropsychopharmacology (01-12-1999)“…Perazine, a piperazine-type phenothiazine neuroleptic, is the most frequently chosen drug for combination with antidepressants in the therapy of complex or…”
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